58 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102207316	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (489 aa)
	LOC102208573	Signal transducer and activator of transcription. (786 aa)
	nrg4	EGF-like domain-containing protein. (109 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (643 aa)
	ENSPNYP00000015963	EGF-like domain-containing protein. (102 aa)
	psenen	Presenilin enhancer, gamma-secretase subunit. (101 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (861 aa)
	LOC102211978	Neuregulin 2a. (695 aa)
	KRAS	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	pik3ca	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSPNYP00000019162	NEDD4 E3 ubiquitin protein ligase a. (362 aa)
	NEDD4	NEDD4 E3 ubiquitin protein ligase. (438 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	itch	E3 ubiquitin-protein ligase. (888 aa)
	LOC102197625	Uncharacterized protein. (376 aa)
	psen2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (430 aa)
	LOC102212942	Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (209 aa)
	uba52	Ubiquitin-like domain-containing protein. (128 aa)
	LOC106456278	Ubiquitin-like domain-containing protein. (122 aa)
	LOC102199268	Erb-b2 receptor tyrosine kinase 3b. (1250 aa)
	LOC102199781	Receptor protein-tyrosine kinase. (1180 aa)
	ENSPNYP00000025883	Zgc:158659; Belongs to the PI3/PI4-kinase family. (474 aa)
	ENSPNYP00000025939	Zgc:158659; Belongs to the PI3/PI4-kinase family. (506 aa)
	aph1a	APH1B gamma secretase subunit. (258 aa)
	ENSPNYP00000030508	Uncharacterized protein. (527 aa)
	LOC102207520	ArfGAP with dual PH domains 2. (374 aa)
	rps27a	Ribosomal protein S27a. (188 aa)
	egf	Epidermal growth factor. (916 aa)
	ADAP2	ArfGAP with dual PH domains 2. (379 aa)
	LOC102214713	DDE_Tnp_1_7 domain-containing protein. (519 aa)
	LOC102203088	Tyrosine-protein kinase. (537 aa)
	wwp1	WW domain containing E3 ubiquitin protein ligase 1. (961 aa)
	nrg2	Neuregulin 2b. (696 aa)
	ADAP1	ArfGAP with dual PH domains 1. (369 aa)
	LOC102203775	Neuregulin 3b. (657 aa)
	LOC102203517	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	NCSTN	Nicastrin. (717 aa)
	wwox	WW domain containing oxidoreductase. (412 aa)
	ENSPNYP00000005212	Ubiquitin-like domain-containing protein. (114 aa)
	ereg	EGF-like domain-containing protein. (130 aa)
	ENSPNYP00000006826	Pkinase_Tyr domain-containing protein. (377 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (451 aa)
	LOC102203381	Uncharacterized protein. (345 aa)
	LOC102215673	Betacellulin, epidermal growth factor family member. (186 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1204 aa)
	SRC	Tyrosine-protein kinase. (464 aa)
	LOC102195379	E3 ubiquitin-protein ligase. (864 aa)
	LOC102207573	Neuregulin 1. (667 aa)
	LOC102198516	Zgc:55558. (186 aa)
	LOC102210707	Signal transducer and activator of transcription. (786 aa)
	ENSPNYP00000011587	Uncharacterized protein. (209 aa)
	erbb4	Receptor protein-tyrosine kinase. (1408 aa)
	yap1	Yes-associated protein 1. (436 aa)
	mxd4	MAX dimerization protein 4. (210 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1237 aa)
	ENSPNYP00000013297	DDE_Tnp_1_7 domain-containing protein. (441 aa)
	LOC102196491	Stathmin; Belongs to the stathmin family. (152 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSPNYP00000005212	ENSPNYP00000018225	ENSPNYP00000005212	Cold shock domain containing E1, RNA-binding.	Ubiquitin-like domain-containing protein.	0.513
CSDE1	ENSPNYP00000006826	ENSPNYP00000018225	ENSPNYP00000006826	Cold shock domain containing E1, RNA-binding.	Pkinase_Tyr domain-containing protein.	0.679
CSDE1	ENSPNYP00000011587	ENSPNYP00000018225	ENSPNYP00000011587	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.480
CSDE1	ENSPNYP00000025883	ENSPNYP00000018225	ENSPNYP00000025883	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.701
CSDE1	ENSPNYP00000025939	ENSPNYP00000018225	ENSPNYP00000025939	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.701
CSDE1	LOC102199268	ENSPNYP00000018225	ENSPNYP00000025030	Cold shock domain containing E1, RNA-binding.	Erb-b2 receptor tyrosine kinase 3b.	0.679
CSDE1	LOC102199781	ENSPNYP00000018225	ENSPNYP00000025315	Cold shock domain containing E1, RNA-binding.	Receptor protein-tyrosine kinase.	0.679
CSDE1	LOC102203088	ENSPNYP00000018225	ENSPNYP00000029008	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.658
CSDE1	LOC102203517	ENSPNYP00000018225	ENSPNYP00000002555	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.701
CSDE1	LOC102207573	ENSPNYP00000018225	ENSPNYP00000009551	Cold shock domain containing E1, RNA-binding.	Neuregulin 1.	0.507
CSDE1	LOC102211978	ENSPNYP00000018225	ENSPNYP00000018250	Cold shock domain containing E1, RNA-binding.	Neuregulin 2a.	0.507
CSDE1	LOC102215673	ENSPNYP00000018225	ENSPNYP00000008281	Cold shock domain containing E1, RNA-binding.	Betacellulin, epidermal growth factor family member.	0.604
CSDE1	LOC106456278	ENSPNYP00000018225	ENSPNYP00000023328	Cold shock domain containing E1, RNA-binding.	Ubiquitin-like domain-containing protein.	0.513
CSDE1	SRC	ENSPNYP00000018225	ENSPNYP00000008672	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.658
CSDE1	egf	ENSPNYP00000018225	ENSPNYP00000027919	Cold shock domain containing E1, RNA-binding.	Epidermal growth factor.	0.618
CSDE1	erbb4	ENSPNYP00000018225	ENSPNYP00000012271	Cold shock domain containing E1, RNA-binding.	Receptor protein-tyrosine kinase.	0.679
CSDE1	ereg	ENSPNYP00000018225	ENSPNYP00000006366	Cold shock domain containing E1, RNA-binding.	EGF-like domain-containing protein.	0.595
CSDE1	grb2	ENSPNYP00000018225	ENSPNYP00000028046	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.781
CSDE1	nrg2	ENSPNYP00000018225	ENSPNYP00000000093	Cold shock domain containing E1, RNA-binding.	Neuregulin 2b.	0.507
CSDE1	pik3ca	ENSPNYP00000018225	ENSPNYP00000019056	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.701