75 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAK3	Non-specific serine/threonine protein kinase. (550 aa)
	uba52	Ubiquitin-like domain-containing protein. (128 aa)
	LOC102194418	MALT paracaspase 1. (776 aa)
	pten	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (411 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	LOC106456278	Ubiquitin-like domain-containing protein. (122 aa)
	LOC102209450	Non-specific serine/threonine protein kinase. (524 aa)
	ENSPNYP00000024048	Protein kinase domain-containing protein. (107 aa)
	card11	Caspase recruitment domain family, member 11. (1073 aa)
	ENSPNYP00000024424	BCL10 immune signaling adaptor. (248 aa)
	LOC102215010	Tyrosine-protein kinase. (578 aa)
	LOC102195620	DDE_Tnp_1_7 domain-containing protein. (604 aa)
	ENSPNYP00000001637	Si:ch211-188c16.1. (513 aa)
	LOC102200386	Ig_4 domain-containing protein. (140 aa)
	plcg1	Phosphoinositide phospholipase C. (1359 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (578 aa)
	fbxw11	F-box and WD repeat domain containing 11a. (520 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (571 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	ENSPNYP00000003284	DDE_Tnp_1_7 domain-containing protein. (584 aa)
	ENSPNYP00000004168	DDE_Tnp_1_7 domain-containing protein. (478 aa)
	ENSPNYP00000005212	Ubiquitin-like domain-containing protein. (114 aa)
	ENSPNYP00000005358	Tyrosine-protein phosphatase domain-containing protein. (127 aa)
	LOC102204333	Protein kinase domain-containing protein. (668 aa)
	ENSPNYP00000007137	HTH_Tnp_Tc3_2 domain-containing protein. (109 aa)
	LOC102212492	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (464 aa)
	PAK2	Non-specific serine/threonine protein kinase. (513 aa)
	LOC102209539	Ig-like domain-containing protein. (380 aa)
	plcg2	Phosphoinositide phospholipase C. (1171 aa)
	map3k20	Sterile alpha motif and leucine zipper containing kinase AZK. (765 aa)
	ikbkb	Inhibitor of nuclear factor kappa B kinase subunit beta. (745 aa)
	ikbkg	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (548 aa)
	pak2	Non-specific serine/threonine protein kinase. (529 aa)
	LOC102213521	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	ptpn12	Uncharacterized protein. (658 aa)
	ENSPNYP00000013934	Ig-like domain-containing protein. (291 aa)
	ENSPNYP00000013984	Uncharacterized protein. (249 aa)
	tab2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (738 aa)
	ENSPNYP00000014088	IGv domain-containing protein. (126 aa)
	ENSPNYP00000014450	Uncharacterized protein. (292 aa)
	ENSPNYP00000014498	Ig-like domain-containing protein. (111 aa)
	ENSPNYP00000014519	IGv domain-containing protein. (119 aa)
	LOC102201953	Ig-like domain-containing protein. (240 aa)
	LOC102202856	MALT paracaspase 3. (548 aa)
	LOC102200506	Uncharacterized protein. (239 aa)
	LOC102201843	GRB2 related adaptor protein 2a. (290 aa)
	pag1	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (446 aa)
	ENSPNYP00000016063	Uncharacterized protein. (850 aa)
	LOC102214838	Immunoglobulin superfamily, member 3. (1056 aa)
	spns1	Spinster homolog 1 (Drosophila). (506 aa)
	LOC102212050	Ubiquitin-conjugating enzyme E2 variant 1. (151 aa)
	LOC102214342	Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	map3k7	Mitogen-activated protein kinase kinase kinase 7. (575 aa)
	LOC102197068	GRB2 related adaptor protein 2b. (227 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa)
	LOC102205606	SH3 domain-containing protein. (469 aa)
	ENSPNYP00000025923	DDE_Tnp_1_7 domain-containing protein. (702 aa)
	inpp5d	Inositol polyphosphate-5-phosphatase D. (1092 aa)
	rps27a	Ribosomal protein S27a. (188 aa)
	LOC106456402	Si:ch211-130m23.5. (682 aa)
	LOC102195172	Protein kinase domain-containing protein. (762 aa)
	LOC102193974	Spinster homolog 3 (Drosophila). (495 aa)
	LOC102195226	Component of inhibitor of nuclear factor kappa B kinase complex. (734 aa)
	ENSPNYP00000028654	Uncharacterized protein. (295 aa)
	LOC102214576	Tyrosine-protein kinase. (451 aa)
	LOC102202408	MALT paracaspase 2. (801 aa)
	LOC102200245	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (305 aa)
	ENSPNYP00000030076	Ig-like domain-containing protein. (125 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
	LOC102213183	Uncharacterized protein. (518 aa)
	LOC102192559	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
	ENSPNYP00000031124	DDE_Tnp_1_7 domain-containing protein. (606 aa)
	LOC102196610	Uncharacterized protein. (101 aa)
	ENSPNYP00000031803	Ig-like domain-containing protein. (122 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	ENSPNYP00000003284	ENSPNYP00000012795	ENSPNYP00000003284	Tyrosine-protein kinase.	DDE_Tnp_1_7 domain-containing protein.	0.497
CSK	ENSPNYP00000004168	ENSPNYP00000012795	ENSPNYP00000004168	Tyrosine-protein kinase.	DDE_Tnp_1_7 domain-containing protein.	0.497
CSK	ENSPNYP00000005212	ENSPNYP00000012795	ENSPNYP00000005212	Tyrosine-protein kinase.	Ubiquitin-like domain-containing protein.	0.421
CSK	ENSPNYP00000005358	ENSPNYP00000012795	ENSPNYP00000005358	Tyrosine-protein kinase.	Tyrosine-protein phosphatase domain-containing protein.	0.835
CSK	ENSPNYP00000007137	ENSPNYP00000012795	ENSPNYP00000007137	Tyrosine-protein kinase.	HTH_Tnp_Tc3_2 domain-containing protein.	0.419
CSK	ENSPNYP00000013934	ENSPNYP00000012795	ENSPNYP00000013934	Tyrosine-protein kinase.	Ig-like domain-containing protein.	0.423
CSK	ENSPNYP00000014088	ENSPNYP00000012795	ENSPNYP00000014088	Tyrosine-protein kinase.	IGv domain-containing protein.	0.436
CSK	ENSPNYP00000014450	ENSPNYP00000012795	ENSPNYP00000014450	Tyrosine-protein kinase.	Uncharacterized protein.	0.423
CSK	ENSPNYP00000014498	ENSPNYP00000012795	ENSPNYP00000014498	Tyrosine-protein kinase.	Ig-like domain-containing protein.	0.425
CSK	ENSPNYP00000024048	ENSPNYP00000012795	ENSPNYP00000024048	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.473
CSK	ENSPNYP00000024424	ENSPNYP00000012795	ENSPNYP00000024424	Tyrosine-protein kinase.	BCL10 immune signaling adaptor.	0.489
CSK	ENSPNYP00000025923	ENSPNYP00000012795	ENSPNYP00000025923	Tyrosine-protein kinase.	DDE_Tnp_1_7 domain-containing protein.	0.497
CSK	ENSPNYP00000031124	ENSPNYP00000012795	ENSPNYP00000031124	Tyrosine-protein kinase.	DDE_Tnp_1_7 domain-containing protein.	0.497
CSK	LOC102192559	ENSPNYP00000012795	ENSPNYP00000030395	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.638
CSK	LOC102195172	ENSPNYP00000012795	ENSPNYP00000027737	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.521
CSK	LOC102195226	ENSPNYP00000012795	ENSPNYP00000028431	Tyrosine-protein kinase.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.521
CSK	LOC102195620	ENSPNYP00000012795	ENSPNYP00000000502	Tyrosine-protein kinase.	DDE_Tnp_1_7 domain-containing protein.	0.497
CSK	LOC102196610	ENSPNYP00000012795	ENSPNYP00000031395	Tyrosine-protein kinase.	Uncharacterized protein.	0.731
CSK	LOC102197068	ENSPNYP00000012795	ENSPNYP00000020237	Tyrosine-protein kinase.	GRB2 related adaptor protein 2b.	0.548
CSK	LOC102200386	ENSPNYP00000012795	ENSPNYP00000001647	Tyrosine-protein kinase.	Ig_4 domain-containing protein.	0.732