19 items (Pundamilia nyererei) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

gene neighborhood

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Your Input:
	LOC102205839	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (587 aa)
	ENSPNYP00000007363	PDZ domain-containing protein. (112 aa)
	tgfbr1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (793 aa)
	cgn	Cingulin a. (1194 aa)
	ENSPNYP00000005212	Ubiquitin-like domain-containing protein. (114 aa)
	rps27a	Ribosomal protein S27a. (188 aa)
	LOC102214447	Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
	LOC102192669	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (613 aa)
	LOC102198874	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (556 aa)
	LOC102203548	F11 receptor, tandem duplicate 2. (298 aa)
	LOC106456278	Ubiquitin-like domain-containing protein. (122 aa)
	ENSPNYP00000022064	Uncharacterized protein. (1021 aa)
	uba52	Ubiquitin-like domain-containing protein. (128 aa)
	LOC102214721	Par-3 family cell polarity regulator alpha, b. (1350 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (542 aa)
	LOC102215979	Par-6 family cell polarity regulator alpha. (406 aa)
	ENSPNYP00000009624	Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1003 aa)
	PARD3	Par-3 family cell polarity regulator. (1209 aa)
	ENSPNYP00000007385	PDZ domain-containing protein. (201 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000005212	ENSPNYP00000007363	ENSPNYP00000005212	ENSPNYP00000007363	Ubiquitin-like domain-containing protein.	PDZ domain-containing protein.	0.600
ENSPNYP00000005212	ENSPNYP00000007385	ENSPNYP00000005212	ENSPNYP00000007385	Ubiquitin-like domain-containing protein.	PDZ domain-containing protein.	0.600
ENSPNYP00000005212	ENSPNYP00000022064	ENSPNYP00000005212	ENSPNYP00000022064	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.600
ENSPNYP00000005212	LOC102192669	ENSPNYP00000005212	ENSPNYP00000031083	Ubiquitin-like domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.502
ENSPNYP00000005212	LOC102198874	ENSPNYP00000005212	ENSPNYP00000031949	Ubiquitin-like domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.611
ENSPNYP00000005212	LOC102205839	ENSPNYP00000005212	ENSPNYP00000007684	Ubiquitin-like domain-containing protein.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.577
ENSPNYP00000005212	LOC102214721	ENSPNYP00000005212	ENSPNYP00000018227	Ubiquitin-like domain-containing protein.	Par-3 family cell polarity regulator alpha, b.	0.622
ENSPNYP00000005212	PARD3	ENSPNYP00000005212	ENSPNYP00000009081	Ubiquitin-like domain-containing protein.	Par-3 family cell polarity regulator.	0.622
ENSPNYP00000005212	TGFBR2	ENSPNYP00000005212	ENSPNYP00000016846	Ubiquitin-like domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.577
ENSPNYP00000005212	rps27a	ENSPNYP00000005212	ENSPNYP00000026531	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.996
ENSPNYP00000005212	tgfbr1	ENSPNYP00000005212	ENSPNYP00000007184	Ubiquitin-like domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.494
ENSPNYP00000007363	ENSPNYP00000005212	ENSPNYP00000007363	ENSPNYP00000005212	PDZ domain-containing protein.	Ubiquitin-like domain-containing protein.	0.600
ENSPNYP00000007363	LOC102192669	ENSPNYP00000007363	ENSPNYP00000031083	PDZ domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.577
ENSPNYP00000007363	LOC102198874	ENSPNYP00000007363	ENSPNYP00000031949	PDZ domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.908
ENSPNYP00000007363	LOC102203548	ENSPNYP00000007363	ENSPNYP00000023592	PDZ domain-containing protein.	F11 receptor, tandem duplicate 2.	0.788
ENSPNYP00000007363	LOC102205839	ENSPNYP00000007363	ENSPNYP00000007684	PDZ domain-containing protein.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.577
ENSPNYP00000007363	LOC102215979	ENSPNYP00000007363	ENSPNYP00000013865	PDZ domain-containing protein.	Par-6 family cell polarity regulator alpha.	0.865
ENSPNYP00000007363	LOC106456278	ENSPNYP00000007363	ENSPNYP00000023328	PDZ domain-containing protein.	Ubiquitin-like domain-containing protein.	0.600
ENSPNYP00000007363	TGFBR2	ENSPNYP00000007363	ENSPNYP00000016846	PDZ domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.577
ENSPNYP00000007363	cgn	ENSPNYP00000007363	ENSPNYP00000007092	PDZ domain-containing protein.	Cingulin a.	0.451