58 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102195747	Cell division cycle 42. (191 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	ENSPNYP00000001252	ZP domain-containing protein. (254 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1125 aa)
	GNB5	Guanine nucleotide binding protein (G protein), beta 5b. (353 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1228 aa)
	LOC102200915	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
	LOC102196269	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	LOC102205279	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	LOC102200425	Guanine nucleotide binding protein (G protein), beta polypeptide 3b. (342 aa)
	LOC102201274	Uncharacterized protein. (191 aa)
	LOC102201940	Uncharacterized protein. (184 aa)
	LOC102204249	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	gnb4	Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (340 aa)
	gng10	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ENSPNYP00000008879	Phosphoinositide phospholipase C. (437 aa)
	ENSPNYP00000008904	PH_14 domain-containing protein. (208 aa)
	gng2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	LOC102215291	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1053 aa)
	LOC102203289	Zona pellucida glycoprotein 3b. (438 aa)
	gnb1	Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
	arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (770 aa)
	gng7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC102213697	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	LOC102204592	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	gng8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	LOC102210817	ZP domain-containing protein. (469 aa)
	LOC102194482	Guanine nucleotide binding protein (G protein), gamma 13a. (67 aa)
	pik3cg	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1122 aa)
	LOC102212032	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	PAK3	Non-specific serine/threonine protein kinase. (550 aa)
	pik3r5	Phosphoinositide-3-kinase, regulatory subunit 5. (838 aa)
	CDC42	Cell division cycle 42. (191 aa)
	ENSPNYP00000021497	Uncharacterized protein. (104 aa)
	PIK3R6	Phosphoinositide-3-kinase regulatory subunit 6. (700 aa)
	LOC102195275	Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	LOC102209450	Non-specific serine/threonine protein kinase. (524 aa)
	gnb2	Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
	LOC102199961	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC102199155	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	LOC102200813	Guanine nucleotide binding protein (G protein), beta 5a. (321 aa)
	ENSPNYP00000027448	Protein kinase domain-containing protein. (102 aa)
	PIK3R5	Phosphoinositide-3-kinase regulatory subunit 5. (744 aa)
	plcb3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1243 aa)
	ENSPNYP00000028247	Uncharacterized protein. (508 aa)
	mfsd6l	Major facilitator superfamily domain containing 6-like. (564 aa)
	mfsd6	Major facilitator superfamily domain containing 6a. (741 aa)
	LOC102199524	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	LOC102200524	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	ENSPNYP00000030097	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (83 aa)
	gnb3	Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (296 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	LOC102195686	Uncharacterized protein. (191 aa)
	gng3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC102192865	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
	ENSPNYP00000031331	PH domain-containing protein. (146 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSPNYP00000027448	ENSPNYP00000021464	ENSPNYP00000027448	Cell division cycle 42.	Protein kinase domain-containing protein.	0.540
CDC42	ENSPNYP00000030097	ENSPNYP00000021464	ENSPNYP00000030097	Cell division cycle 42.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.525
CDC42	ENSPNYP00000031331	ENSPNYP00000021464	ENSPNYP00000031331	Cell division cycle 42.	PH domain-containing protein.	0.540
CDC42	GNB5	ENSPNYP00000021464	ENSPNYP00000001587	Cell division cycle 42.	Guanine nucleotide binding protein (G protein), beta 5b.	0.719
CDC42	GNG5	ENSPNYP00000021464	ENSPNYP00000030411	Cell division cycle 42.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.629
CDC42	LOC102192865	ENSPNYP00000021464	ENSPNYP00000031119	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.540
CDC42	LOC102195275	ENSPNYP00000021464	ENSPNYP00000022103	Cell division cycle 42.	Guanine nucleotide binding protein (G protein), beta polypeptide 1b.	0.648
CDC42	LOC102195686	ENSPNYP00000021464	ENSPNYP00000030506	Cell division cycle 42.	Uncharacterized protein.	0.665
CDC42	LOC102196269	ENSPNYP00000021464	ENSPNYP00000002294	Cell division cycle 42.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.470
CDC42	LOC102199524	ENSPNYP00000021464	ENSPNYP00000028748	Cell division cycle 42.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.525
CDC42	LOC102200425	ENSPNYP00000021464	ENSPNYP00000003189	Cell division cycle 42.	Guanine nucleotide binding protein (G protein), beta polypeptide 3b.	0.454
CDC42	LOC102200524	ENSPNYP00000021464	ENSPNYP00000029866	Cell division cycle 42.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.470
CDC42	LOC102200813	ENSPNYP00000021464	ENSPNYP00000026718	Cell division cycle 42.	Guanine nucleotide binding protein (G protein), beta 5a.	0.719
CDC42	LOC102200915	ENSPNYP00000021464	ENSPNYP00000001886	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.540
CDC42	LOC102201274	ENSPNYP00000021464	ENSPNYP00000003331	Cell division cycle 42.	Uncharacterized protein.	0.665
CDC42	LOC102201940	ENSPNYP00000021464	ENSPNYP00000003374	Cell division cycle 42.	Uncharacterized protein.	0.669
CDC42	LOC102205279	ENSPNYP00000021464	ENSPNYP00000003130	Cell division cycle 42.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.525
CDC42	LOC102209450	ENSPNYP00000021464	ENSPNYP00000023782	Cell division cycle 42.	Non-specific serine/threonine protein kinase.	0.970
CDC42	LOC102213697	ENSPNYP00000021464	ENSPNYP00000017716	Cell division cycle 42.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.540
CDC42	LOC102215291	ENSPNYP00000021464	ENSPNYP00000012914	Cell division cycle 42.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.601