STRINGSTRING
ENSPNYP00000008879 ENSPNYP00000008879 kcnb1 kcnb1 ENSPNYP00000009520 ENSPNYP00000009520 rapgef4 rapgef4 ENSPNYP00000010405 ENSPNYP00000010405 CACNA1E CACNA1E ENSPNYP00000010747 ENSPNYP00000010747 ENSPNYP00000010776 ENSPNYP00000010776 LOC102210075 LOC102210075 gng2 gng2 LOC102195906 LOC102195906 CACNA1D CACNA1D LOC102210552 LOC102210552 LOC102203289 LOC102203289 acsl3 acsl3 marcks marcks adcy5 adcy5 gnb1 gnb1 LOC102213139 LOC102213139 LOC102213426 LOC102213426 LOC102197394 LOC102197394 gng7 gng7 LOC102192069 LOC102192069 LOC102204592 LOC102204592 itpr2 itpr2 GNG4 GNG4 gng8 gng8 LOC102211595 LOC102211595 ENSPNYP00000018984 ENSPNYP00000018984 LOC102210817 LOC102210817 ENSPNYP00000019107 ENSPNYP00000019107 ENSPNYP00000019127 ENSPNYP00000019127 LOC102206431 LOC102206431 LOC102194482 LOC102194482 LOC102211734 LOC102211734 LOC102215393 LOC102215393 cacna1a cacna1a LOC102212032 LOC102212032 LOC102206787 LOC102206787 LOC102195275 LOC102195275 cacna2d2 cacna2d2 ENSPNYP00000023088 ENSPNYP00000023088 LOC102206396 LOC102206396 LOC102195503 LOC102195503 cd36 cd36 gnb2 gnb2 LOC102199961 LOC102199961 LOC102199155 LOC102199155 thap7 thap7 LOC102200813 LOC102200813 LOC102210772 LOC102210772 cacna1c cacna1c cacna1s cacna1s adcy6 adcy6 LOC102203592 LOC102203592 plcb3 plcb3 LOC102200029 LOC102200029 LOC102212710 LOC102212710 LOC102199524 LOC102199524 abcc8 abcc8 ENSPNYP00000028911 ENSPNYP00000028911 LOC102205436 LOC102205436 LOC102205713 LOC102205713 LOC102200524 LOC102200524 ENSPNYP00000030097 ENSPNYP00000030097 prkacb prkacb gnb3 gnb3 GNG5 GNG5 LOC102199453 LOC102199453 gng3 gng3 LOC102201680 LOC102201680 PLCB1 PLCB1 GNB5 GNB5 PLCB2 PLCB2 LOC102196269 LOC102196269 adra2a adra2a LOC102209690 LOC102209690 LOC102205279 LOC102205279 LOC102200425 LOC102200425 gcg gcg LOC102203222 LOC102203222 LOC102204249 LOC102204249 LOC102215704 LOC102215704 prkaca prkaca LOC102215815 LOC102215815 LOC102198472 LOC102198472 LOC102204626 LOC102204626 LOC102211041 LOC102211041 gnb4 gnb4 LOC102211142 LOC102211142 itpr3 itpr3 LOC102211711 LOC102211711 ADRA2C ADRA2C slc2a2 slc2a2 LOC102205644 LOC102205644 gng10 gng10 ENSPNYP00000008765 ENSPNYP00000008765 ENSPNYP00000008904 ENSPNYP00000008904 acsl4 acsl4 ENSPNYP00000000591 ENSPNYP00000000591 cacnb2 cacnb2 ENSPNYP00000000934 ENSPNYP00000000934 THAP1 THAP1 ENSPNYP00000001252 ENSPNYP00000001252
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPNYP00000008879Phosphoinositide phospholipase C. (437 aa)
kcnb1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (793 aa)
ENSPNYP00000009520VWFA domain-containing protein. (374 aa)
rapgef4Rap guanine nucleotide exchange factor (GEF) 4. (999 aa)
ENSPNYP00000010405Uncharacterized protein. (411 aa)
CACNA1ECalcium voltage-gated channel subunit alpha1 E. (733 aa)
ENSPNYP00000010747Rap guanine nucleotide exchange factor (GEF) 5a. (553 aa)
ENSPNYP00000010776DEP domain-containing protein. (241 aa)
LOC102210075Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
LOC102195906Acyl-CoA synthetase long chain family member 3b. (711 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1997 aa)
LOC102210552Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2099 aa)
LOC102203289Zona pellucida glycoprotein 3b. (438 aa)
acsl3AMP-binding domain-containing protein. (719 aa)
marcksMyristoylated alanine-rich protein kinase C substrate a. (271 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
gnb1Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
LOC102213139Uncharacterized protein. (359 aa)
LOC102213426Guanine nucleotide binding protein (G protein), alpha 14a. (348 aa)
LOC102197394Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2195 aa)
gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC102192069Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
LOC102204592Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2672 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
gng8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC102211595Uncharacterized protein. (596 aa)
ENSPNYP00000018984Uncharacterized protein. (292 aa)
LOC102210817ZP domain-containing protein. (469 aa)
ENSPNYP00000019107Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1172 aa)
ENSPNYP00000019127Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
LOC102206431Potassium voltage-gated channel, Shab-related subfamily, member 1; Belongs to the potassium channel family. (838 aa)
LOC102194482Guanine nucleotide binding protein (G protein), gamma 13a. (67 aa)
LOC102211734Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
LOC102215393Calcium channel, voltage-dependent, R type, alpha 1E subunit b. (2037 aa)
cacna1aVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2284 aa)
LOC102212032Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
LOC102206787Calcium channel, voltage-dependent, beta 2b. (397 aa)
LOC102195275Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
cacna2d2Calcium channel, voltage-dependent, alpha 2/delta subunit 2a. (1105 aa)
ENSPNYP00000023088Rap guanine nucleotide exchange factor (GEF)-like 1. (368 aa)
LOC102206396Uncharacterized protein. (354 aa)
LOC102195503Sorting nexin 19a. (862 aa)
cd36CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (468 aa)
gnb2Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
LOC102199961Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC102199155Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
thap7THAP-type domain-containing protein. (597 aa)
LOC102200813Guanine nucleotide binding protein (G protein), beta 5a. (321 aa)
LOC102210772Calcium channel, voltage-dependent, alpha 2/delta subunit 2b. (1046 aa)
cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1909 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1760 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
LOC102203592Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1756 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1243 aa)
LOC102200029Inositol 1,4,5-trisphosphate receptor, type 1a. (2669 aa)
LOC102212710Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC102199524Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 8. (1561 aa)
ENSPNYP00000028911Potassium inwardly-rectifying channel, subfamily J, member 11. (383 aa)
LOC102205436Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4. (369 aa)
LOC102205713Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
LOC102200524Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSPNYP00000030097Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (83 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (381 aa)
gnb3Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (296 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC102199453Potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b; Belongs to the potassium channel family. (498 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC102201680Sorting nexin 19b. (981 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1125 aa)
GNB5Guanine nucleotide binding protein (G protein), beta 5b. (353 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1228 aa)
LOC102196269Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
adra2aAdrenoceptor alpha 2A. (428 aa)
LOC102209690Uncharacterized protein. (355 aa)
LOC102205279Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC102200425Guanine nucleotide binding protein (G protein), beta polypeptide 3b. (342 aa)
gcgGlucagon b. (120 aa)
LOC102203222Inositol 1,4,5-trisphosphate receptor, type 1b. (2693 aa)
LOC102204249Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC102215704Rap guanine nucleotide exchange factor (GEF) 3. (867 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (343 aa)
LOC102215815Solute carrier family 2 member 1b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (490 aa)
LOC102198472Potassium voltage-gated channel, subfamily G, member 2; Belongs to the potassium channel family. (533 aa)
LOC102204626Zgc:171558. (868 aa)
LOC102211041Si:dkey-211g8.9. (263 aa)
gnb4Guanine nucleotide binding protein (G protein), beta polypeptide 4b. (340 aa)
LOC102211142Guanine nucleotide binding protein (G protein), alpha 14. (356 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2586 aa)
LOC102211711Uncharacterized protein. (374 aa)
ADRA2CAdrenoceptor alpha 2C. (389 aa)
slc2a2Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (500 aa)
LOC102205644Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSPNYP00000008765Adrenoceptor alpha 2C. (392 aa)
ENSPNYP00000008904PH_14 domain-containing protein. (208 aa)
acsl4Acyl-CoA synthetase long chain family member 4a. (712 aa)
ENSPNYP00000000591Potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3a; Belongs to the potassium channel family. (480 aa)
cacnb2Calcium channel, voltage-dependent, beta 2a. (598 aa)
ENSPNYP00000000934VWA_N domain-containing protein. (265 aa)
THAP1THAP domain containing 1. (227 aa)
ENSPNYP00000001252ZP domain-containing protein. (254 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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