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CSDE1 CSDE1 mknk2 mknk2 fgf4 fgf4 pik3ca pik3ca fgf1 fgf1 cblc cblc hras hras uba52 uba52 FGF6 FGF6 fgf23 fgf23 LOC102209716 LOC102209716 cbl cbl LOC106456278 LOC106456278 ppp2r1b ppp2r1b ENSPNYP00000025883 ENSPNYP00000025883 ENSPNYP00000025939 ENSPNYP00000025939 LOC102206905 LOC102206905 FGF6-2 FGF6-2 rps27a rps27a grb2 grb2 LOC102214713 LOC102214713 LOC102203088 LOC102203088 ENSPNYP00000030508 ENSPNYP00000030508 LOC102198360 LOC102198360 fgf16 fgf16 LOC102193983 LOC102193983 LOC102199590 LOC102199590 LOC102198584 LOC102198584 LOC102211268 LOC102211268 plcg1 plcg1 fgf20 fgf20 fgf2 fgf2 fgf18 fgf18 LOC102203517 LOC102203517 fgf8 fgf8 fgf19 fgf19 ENSPNYP00000005212 ENSPNYP00000005212 ENSPNYP00000006720 ENSPNYP00000006720 shc1 shc1 mapk1 mapk1 LOC102199714 LOC102199714 LOC102194035 LOC102194035 LOC102207741 LOC102207741 fndc3b fndc3b SRC SRC ENSPNYP00000009163 ENSPNYP00000009163 ENSPNYP00000010154 ENSPNYP00000010154 LOC102198516 LOC102198516 ENSPNYP00000011587 ENSPNYP00000011587 fndc3a fndc3a ENSPNYP00000013297 ENSPNYP00000013297 CBL CBL gab1 gab1 ppp2ca ppp2ca KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSDE1Cold shock domain containing E1, RNA-binding. (861 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (461 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (152 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (506 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
uba52Ubiquitin-like domain-containing protein. (128 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (262 aa)
LOC102209716Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
LOC106456278Ubiquitin-like domain-containing protein. (122 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
ENSPNYP00000025883Zgc:158659; Belongs to the PI3/PI4-kinase family. (474 aa)
ENSPNYP00000025939Zgc:158659; Belongs to the PI3/PI4-kinase family. (506 aa)
LOC102206905Fibroblast growth factor receptor substrate 3. (510 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
rps27aRibosomal protein S27a. (188 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC102214713DDE_Tnp_1_7 domain-containing protein. (519 aa)
LOC102203088Tyrosine-protein kinase. (537 aa)
ENSPNYP00000030508Uncharacterized protein. (527 aa)
LOC102198360Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC102193983Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC102199590Serine/threonine-protein phosphatase. (309 aa)
LOC102198584PH domain-containing protein. (380 aa)
LOC102211268Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
plcg1Phosphoinositide phospholipase C. (1359 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
fgf18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
LOC102203517Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSPNYP00000005212Ubiquitin-like domain-containing protein. (114 aa)
ENSPNYP00000006720Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (451 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (334 aa)
LOC102199714Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
LOC102194035Fibroblast growth factor receptor substrate 2b. (525 aa)
LOC102207741MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)
fndc3bFibronectin type III domain containing 3Ba. (1204 aa)
SRCTyrosine-protein kinase. (464 aa)
ENSPNYP00000009163Metallophos domain-containing protein. (129 aa)
ENSPNYP00000010154Sprouty RTK signaling antagonist 2. (298 aa)
LOC102198516Zgc:55558. (186 aa)
ENSPNYP00000011587Uncharacterized protein. (209 aa)
fndc3aFibronectin type III domain containing 3A. (1237 aa)
ENSPNYP00000013297DDE_Tnp_1_7 domain-containing protein. (441 aa)
CBLCbl proto-oncogene. (519 aa)
gab1GRB2-associated binding protein 1. (713 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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