STRINGSTRING
LOC102213923 LOC102213923 rps27a rps27a LOC102214620 LOC102214620 sumo1 sumo1 ENSPNYP00000029649 ENSPNYP00000029649 ppp5c ppp5c mdc1 mdc1 ENSPNYP00000030315 ENSPNYP00000030315 rnf168 rnf168 rnf8 rnf8 ENSPNYP00000031615 ENSPNYP00000031615 smarca5 smarca5 brca1 brca1 LOC102204139 LOC102204139 eya1 eya1 kxd1 kxd1 tp53bp1 tp53bp1 apbb1 apbb1 LOC102209951 LOC102209951 ENSPNYP00000005212 ENSPNYP00000005212 ENSPNYP00000006437 ENSPNYP00000006437 ankrd11 ankrd11 LOC102214393 LOC102214393 ENSPNYP00000006654 ENSPNYP00000006654 ENSPNYP00000006710 ENSPNYP00000006710 ENSPNYP00000006833 ENSPNYP00000006833 ENSPNYP00000007155 ENSPNYP00000007155 ankrd12 ankrd12 nbn nbn ENSPNYP00000008349 ENSPNYP00000008349 ENSPNYP00000008816 ENSPNYP00000008816 abl1 abl1 LOC102213521 LOC102213521 ENSPNYP00000000760 ENSPNYP00000000760 ENSPNYP00000000749 ENSPNYP00000000749 babam2 babam2 rnf169 rnf169 abraxas1 abraxas1 atm atm LOC102207428 LOC102207428 baz1b baz1b eya4 eya4 LOC102214342 LOC102214342 babam1 babam1 LOC102215705 LOC102215705 ENSPNYP00000019133 ENSPNYP00000019133 ube2v2 ube2v2 rad50 rad50 LOC102199873 LOC102199873 ENSPNYP00000021180 ENSPNYP00000021180 uba52 uba52 pias4 pias4 kat5 kat5 ube2i ube2i ENSPNYP00000023158 ENSPNYP00000023158 ENSPNYP00000023182 ENSPNYP00000023182 LOC106456278 LOC106456278 KPNA2 KPNA2 LOC102212740 LOC102212740 mre11 mre11 ENSPNYP00000025405 ENSPNYP00000025405 H4C6 H4C6 ENSPNYP00000031920 ENSPNYP00000031920
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102213923Lysine (K)-specific demethylase 4B. (1241 aa)
rps27aRibosomal protein S27a. (188 aa)
LOC102214620Importin subunit alpha; Belongs to the importin alpha family. (523 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
ENSPNYP00000029649Histone H2B; Belongs to the histone H2B family. (282 aa)
ppp5cSerine/threonine-protein phosphatase. (479 aa)
mdc1Uncharacterized protein. (1729 aa)
ENSPNYP00000030315Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (140 aa)
rnf168Ring finger protein 168. (404 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (467 aa)
ENSPNYP00000031615Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (87 aa)
smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (652 aa)
brca1Uncharacterized protein. (1180 aa)
LOC102204139Importin subunit alpha; Belongs to the importin alpha family. (525 aa)
eya1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (614 aa)
kxd1KxDL motif containing 1. (184 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1473 aa)
apbb1Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65). (682 aa)
LOC102209951Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (607 aa)
ENSPNYP00000005212Ubiquitin-like domain-containing protein. (114 aa)
ENSPNYP00000006437Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (97 aa)
ankrd11Ankyrin repeat domain 11. (2845 aa)
LOC102214393Histone H2B; Belongs to the histone H2B family. (124 aa)
ENSPNYP00000006654Reverse transcriptase domain-containing protein. (471 aa)
ENSPNYP00000006710Histone H2B; Belongs to the histone H2B family. (116 aa)
ENSPNYP00000006833Uncharacterized protein. (255 aa)
ENSPNYP00000007155Histone H2A; Belongs to the histone H2A family. (141 aa)
ankrd12Ankyrin repeat domain 12. (1926 aa)
nbnNibrin. (776 aa)
ENSPNYP00000008349Reverse transcriptase domain-containing protein. (163 aa)
ENSPNYP00000008816Tumor protein p53. (357 aa)
abl1Tyrosine-protein kinase. (1112 aa)
LOC102213521UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
ENSPNYP00000000760Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
ENSPNYP00000000749Uncharacterized protein. (95 aa)
babam2BRISC and BRCA1 A complex member 2. (400 aa)
rnf169Ring finger protein 169. (585 aa)
abraxas1Abraxas 1, BRCA1 A complex subunit. (346 aa)
atmNon-specific serine/threonine protein kinase. (3051 aa)
LOC102207428Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (449 aa)
baz1bBromodomain adjacent to zinc finger domain, 1B. (1395 aa)
eya4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (649 aa)
LOC102214342Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
babam1BRISC and BRCA1 A complex member 1. (326 aa)
LOC102215705Checkpoint kinase 2. (476 aa)
ENSPNYP00000019133RAP80_UIM domain-containing protein. (609 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (158 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
LOC102199873Histone H2B; Belongs to the histone H2B family. (114 aa)
ENSPNYP00000021180BRCA1/BRCA2-containing complex, subunit 3. (278 aa)
uba52Ubiquitin-like domain-containing protein. (128 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
ENSPNYP00000023158Nuclear receptor binding SET domain protein 2. (465 aa)
ENSPNYP00000023182PWWP domain-containing protein. (156 aa)
LOC106456278Ubiquitin-like domain-containing protein. (122 aa)
KPNA2Importin subunit alpha; Belongs to the importin alpha family. (524 aa)
LOC102212740UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (689 aa)
ENSPNYP00000025405Uncharacterized protein. (98 aa)
H4C6Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSPNYP00000031920Ig-like domain-containing protein. (308 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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