STRINGSTRING
parp1 parp1 LOC102193700 LOC102193700 ENSPNYP00000011207 ENSPNYP00000011207 LOC102200240 LOC102200240 parp3 parp3 usp45 usp45 ENSPNYP00000005212 ENSPNYP00000005212 LOC102196725 LOC102196725 ENSPNYP00000004582 ENSPNYP00000004582 parp2 parp2 ENSPNYP00000004552 ENSPNYP00000004552 ercc4 ercc4 cul4a cul4a kxd1 kxd1 LOC102213342 LOC102213342 LOC102207357 LOC102207357 xpa xpa ercc3 ercc3 ENSPNYP00000000447 ENSPNYP00000000447 rpa2 rpa2 gtf2h3 gtf2h3 rnf111 rnf111 LOC102214342 LOC102214342 chd1l chd1l ENSPNYP00000016413 ENSPNYP00000016413 gtf2h5 gtf2h5 rpa3 rpa3 xpc xpc cetn3 cetn3 LOC102208280 LOC102208280 gtf2h4 gtf2h4 cul4b cul4b LOC102213521 LOC102213521 LOC102203234 LOC102203234 RPA1 RPA1 rbx1 rbx1 LOC102208173 LOC102208173 mnat1 mnat1 ercc2 ercc2 sumo1 sumo1 meiob meiob ccnh ccnh rps27a rps27a LOC102204724 LOC102204724 ercc1 ercc1 ENSPNYP00000025590 ENSPNYP00000025590 cdk7 cdk7 rad23a rad23a ube2v2 ube2v2 ddb2 ddb2 LOC102203776 LOC102203776 LOC102212432 LOC102212432 gtf2h1 gtf2h1 LOC102215177 LOC102215177 uba52 uba52 ube2i ube2i LOC106456278 LOC106456278 LOC102212740 LOC102212740 pias1 pias1 bivm bivm ENSPNYP00000019396 ENSPNYP00000019396
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (999 aa)
LOC102193700Von Willebrand factor A domain containing 5B2. (1035 aa)
ENSPNYP00000011207Ubiquitin-like domain-containing protein. (128 aa)
LOC102200240Protein inhibitor of activated STAT 1. (586 aa)
parp3Poly [ADP-ribose] polymerase. (532 aa)
usp45Ubiquitin carboxyl-terminal hydrolase. (847 aa)
ENSPNYP00000005212Ubiquitin-like domain-containing protein. (114 aa)
LOC102196725Uncharacterized protein. (471 aa)
ENSPNYP00000004582XPGN domain-containing protein. (222 aa)
parp2Poly [ADP-ribose] polymerase. (641 aa)
ENSPNYP00000004552Excision repair cross-complementation group 5. (853 aa)
ercc4Excision repair cross-complementation group 4. (886 aa)
cul4aCullin 4A; Belongs to the cullin family. (692 aa)
kxd1KxDL motif containing 1. (184 aa)
LOC102213342Centrin 4. (185 aa)
LOC102207357Small ubiquitin-related modifier. (94 aa)
xpaXeroderma pigmentosum, complementation group A. (271 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
ENSPNYP00000000447Uncharacterized protein. (64 aa)
rpa2Replication protein A2. (293 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (294 aa)
rnf111Ring finger protein 111. (1007 aa)
LOC102214342Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (894 aa)
ENSPNYP00000016413Rad60-SLD domain-containing protein. (104 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
rpa3Replication protein A3. (122 aa)
xpcXeroderma pigmentosum, complementation group C. (892 aa)
cetn3Centrin 3. (167 aa)
LOC102208280Damage-specific DNA binding protein 1. (562 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
cul4bCullin 4B; Belongs to the cullin family. (865 aa)
LOC102213521UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
LOC102203234Damage-specific DNA binding protein 1. (573 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (640 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
LOC102208173Si:dkey-117m1.4. (834 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
meiobMethionine sulfoxide reductase B1b. (456 aa)
ccnhCyclin H; Belongs to the cyclin family. (343 aa)
rps27aRibosomal protein S27a. (188 aa)
LOC102204724General transcription factor IIH subunit. (392 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
ENSPNYP00000025590WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (305 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (396 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (158 aa)
ddb2Damage-specific DNA binding protein 2. (490 aa)
LOC102203776Small ubiquitin-related modifier. (94 aa)
LOC102212432Small ubiquitin-related modifier. (96 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (513 aa)
LOC102215177Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
uba52Ubiquitin-like domain-containing protein. (128 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC106456278Ubiquitin-like domain-containing protein. (122 aa)
LOC102212740UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
pias1Protein inhibitor of activated STAT, 1b. (654 aa)
bivmBasic, immunoglobulin-like variable motif containing. (496 aa)
ENSPNYP00000019396Rad60-SLD domain-containing protein. (72 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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