30 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	atad5	AAA domain-containing protein. (746 aa)
	pole3	Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
	ENSPNYP00000005212	Ubiquitin-like domain-containing protein. (114 aa)
	rfc2	Replication factor C (activator 1) 2. (356 aa)
	pold4	Si:dkey-28b4.7. (107 aa)
	rfc5	Replication factor C (activator 1) 5. (342 aa)
	pold1	DNA polymerase. (1105 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	rcbtb2	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	rpa3	Replication protein A3. (122 aa)
	rfc4	Replication factor C (activator 1) 4. (357 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	ENSPNYP00000018622	Uncharacterized protein. (967 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (640 aa)
	rfc1	Replication factor C subunit 1. (1153 aa)
	pole4	Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
	meiob	Methionine sulfoxide reductase B1b. (456 aa)
	rps27a	Ribosomal protein S27a. (188 aa)
	ENSPNYP00000025918	Polymerase (DNA directed) kappa. (409 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
	LOC106456278	Ubiquitin-like domain-containing protein. (122 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (509 aa)
	pole	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2015 aa)
	uba52	Ubiquitin-like domain-containing protein. (128 aa)
	LOC102215177	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (443 aa)
	LOC102201896	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
	rpa2	Replication protein A2. (293 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000005212	ENSPNYP00000025918	ENSPNYP00000005212	ENSPNYP00000025918	Ubiquitin-like domain-containing protein.	Polymerase (DNA directed) kappa.	0.789
ENSPNYP00000005212	pcna	ENSPNYP00000005212	ENSPNYP00000011905	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.937
ENSPNYP00000005212	pold1	ENSPNYP00000005212	ENSPNYP00000011516	Ubiquitin-like domain-containing protein.	DNA polymerase.	0.677
ENSPNYP00000005212	pole	ENSPNYP00000005212	ENSPNYP00000022373	Ubiquitin-like domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.665
ENSPNYP00000005212	rfc2	ENSPNYP00000005212	ENSPNYP00000006331	Ubiquitin-like domain-containing protein.	Replication factor C (activator 1) 2.	0.631
ENSPNYP00000005212	rfc3	ENSPNYP00000005212	ENSPNYP00000018085	Ubiquitin-like domain-containing protein.	Replication factor C (activator 1) 3.	0.631
ENSPNYP00000005212	rfc4	ENSPNYP00000005212	ENSPNYP00000016083	Ubiquitin-like domain-containing protein.	Replication factor C (activator 1) 4.	0.631
ENSPNYP00000005212	rfc5	ENSPNYP00000005212	ENSPNYP00000010554	Ubiquitin-like domain-containing protein.	Replication factor C (activator 1) 5.	0.631
ENSPNYP00000005212	rpa2	ENSPNYP00000005212	ENSPNYP00000018682	Ubiquitin-like domain-containing protein.	Replication protein A2.	0.602
ENSPNYP00000005212	rps27a	ENSPNYP00000005212	ENSPNYP00000026531	Ubiquitin-like domain-containing protein.	Ribosomal protein S27a.	0.996
ENSPNYP00000018622	ENSPNYP00000025918	ENSPNYP00000018622	ENSPNYP00000025918	Uncharacterized protein.	Polymerase (DNA directed) kappa.	0.671
ENSPNYP00000018622	LOC102215177	ENSPNYP00000018622	ENSPNYP00000021640	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.818
ENSPNYP00000018622	RPA1	ENSPNYP00000018622	ENSPNYP00000032019	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.818
ENSPNYP00000018622	meiob	ENSPNYP00000018622	ENSPNYP00000027578	Uncharacterized protein.	Methionine sulfoxide reductase B1b.	0.818
ENSPNYP00000018622	pcna	ENSPNYP00000018622	ENSPNYP00000011905	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.972
ENSPNYP00000018622	pold1	ENSPNYP00000018622	ENSPNYP00000011516	Uncharacterized protein.	DNA polymerase.	0.842
ENSPNYP00000018622	pold2	ENSPNYP00000018622	ENSPNYP00000024214	Uncharacterized protein.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.727
ENSPNYP00000018622	pold3	ENSPNYP00000018622	ENSPNYP00000021459	Uncharacterized protein.	Polymerase (DNA-directed), delta 3, accessory subunit.	0.730
ENSPNYP00000018622	pold4	ENSPNYP00000018622	ENSPNYP00000010068	Uncharacterized protein.	Si:dkey-28b4.7.	0.534
ENSPNYP00000018622	pole	ENSPNYP00000018622	ENSPNYP00000022373	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.900