82 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1182 aa)
	hmgn5	High mobility group nucleosome binding domain 6. (87 aa)
	LOC102212161	Si:ch73-1a9.3. (84 aa)
	prpf19	Pre-mRNA processing factor 19. (505 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	lig1	DNA ligase. (1012 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	atad5	AAA domain-containing protein. (746 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (692 aa)
	pole3	Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
	ENSPNYP00000005212	Ubiquitin-like domain-containing protein. (114 aa)
	LOC102210571	E1A binding protein p300 a. (2779 aa)
	rfc2	Replication factor C (activator 1) 2. (356 aa)
	ENSPNYP00000006853	TFIIS N-terminal domain-containing protein. (108 aa)
	ENSPNYP00000006869	Transcription elongation factor A (SII), 3. (170 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (299 aa)
	tceanc2	Uncharacterized protein. (207 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	pold4	Si:dkey-28b4.7. (107 aa)
	rfc5	Replication factor C (activator 1) 5. (342 aa)
	pold1	DNA polymerase. (1105 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	ercc8	Excision repair cross-complementation group 8. (409 aa)
	rcbtb2	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (527 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (865 aa)
	ercc6	Excision repair cross-complementation group 6. (1408 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	LOC102208280	Damage-specific DNA binding protein 1. (562 aa)
	rpa3	Replication protein A3. (122 aa)
	polr2i	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	rfc4	Replication factor C (activator 1) 4. (357 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	polr2k	Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
	lig3	DNA ligase. (1012 aa)
	uvssa	UV-stimulated scaffold protein A. (774 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (294 aa)
	ENSPNYP00000018622	Uncharacterized protein. (967 aa)
	rpa2	Replication protein A2. (293 aa)
	xab2	XPA binding protein 2. (849 aa)
	ZNF830	Zinc finger protein 830. (345 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	LOC102214201	Transcription elongation factor A (SII), 2. (290 aa)
	TCEANC	Transcription elongation factor A N-terminal and central domain containing. (334 aa)
	LOC102201896	Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (531 aa)
	usp40	Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1290 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (513 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (172 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (443 aa)
	LOC102215177	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
	tcea1	Transcription elongation factor A (SII), 1. (311 aa)
	uba52	Ubiquitin-like domain-containing protein. (128 aa)
	aqr	Aquarius intron-binding spliceosomal factor. (1472 aa)
	pole	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2015 aa)
	pole2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (509 aa)
	LOC106456278	Ubiquitin-like domain-containing protein. (122 aa)
	pold2	Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	phf3	PHD finger protein 3. (1733 aa)
	ENSPNYP00000025918	Polymerase (DNA directed) kappa. (409 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
	POLR2E	RNA polymerase II subunit E. (198 aa)
	LOC102204724	General transcription factor IIH subunit. (392 aa)
	rps27a	Ribosomal protein S27a. (188 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (343 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	meiob	Methionine sulfoxide reductase B1b. (456 aa)
	pole4	Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1966 aa)
	nrde2	NRDE-2, necessary for RNA interference, domain containing. (1152 aa)
	rfc1	Replication factor C subunit 1. (1153 aa)
	polr2d	RPOL4c domain-containing protein. (112 aa)
	LOC102213167	E1A binding protein p300 b. (2553 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (640 aa)
	LOC102203234	Damage-specific DNA binding protein 1. (573 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000005212	ENSPNYP00000006853	ENSPNYP00000005212	ENSPNYP00000006853	Ubiquitin-like domain-containing protein.	TFIIS N-terminal domain-containing protein.	0.611
ENSPNYP00000005212	ENSPNYP00000006869	ENSPNYP00000005212	ENSPNYP00000006869	Ubiquitin-like domain-containing protein.	Transcription elongation factor A (SII), 3.	0.611
ENSPNYP00000005212	ENSPNYP00000025918	ENSPNYP00000005212	ENSPNYP00000025918	Ubiquitin-like domain-containing protein.	Polymerase (DNA directed) kappa.	0.789
ENSPNYP00000005212	LOC102203234	ENSPNYP00000005212	ENSPNYP00000032109	Ubiquitin-like domain-containing protein.	Damage-specific DNA binding protein 1.	0.622
ENSPNYP00000005212	LOC102208280	ENSPNYP00000005212	ENSPNYP00000013871	Ubiquitin-like domain-containing protein.	Damage-specific DNA binding protein 1.	0.622
ENSPNYP00000005212	LOC102214201	ENSPNYP00000005212	ENSPNYP00000020178	Ubiquitin-like domain-containing protein.	Transcription elongation factor A (SII), 2.	0.611
ENSPNYP00000005212	POLR2E	ENSPNYP00000005212	ENSPNYP00000026248	Ubiquitin-like domain-containing protein.	RNA polymerase II subunit E.	0.845
ENSPNYP00000005212	TCEANC	ENSPNYP00000005212	ENSPNYP00000020230	Ubiquitin-like domain-containing protein.	Transcription elongation factor A N-terminal and central domain containing.	0.605
ENSPNYP00000005212	ercc3	ENSPNYP00000005212	ENSPNYP00000001548	Ubiquitin-like domain-containing protein.	Excision repair cross-complementation group 3.	0.650
ENSPNYP00000005212	ercc6	ENSPNYP00000005212	ENSPNYP00000013460	Ubiquitin-like domain-containing protein.	Excision repair cross-complementation group 6.	0.905
ENSPNYP00000005212	gtf2h5	ENSPNYP00000005212	ENSPNYP00000016092	Ubiquitin-like domain-containing protein.	General transcription factor IIH, polypeptide 5.	0.581
ENSPNYP00000005212	hmgn5	ENSPNYP00000005212	ENSPNYP00000000146	Ubiquitin-like domain-containing protein.	High mobility group nucleosome binding domain 6.	0.975
ENSPNYP00000005212	pcna	ENSPNYP00000005212	ENSPNYP00000011905	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.937
ENSPNYP00000005212	pold1	ENSPNYP00000005212	ENSPNYP00000011516	Ubiquitin-like domain-containing protein.	DNA polymerase.	0.677
ENSPNYP00000005212	pole	ENSPNYP00000005212	ENSPNYP00000022373	Ubiquitin-like domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.665
ENSPNYP00000005212	polr2a	ENSPNYP00000005212	ENSPNYP00000029673	Ubiquitin-like domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.624
ENSPNYP00000005212	polr2b	ENSPNYP00000005212	ENSPNYP00000000003	Ubiquitin-like domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.771
ENSPNYP00000005212	polr2c	ENSPNYP00000005212	ENSPNYP00000004840	Ubiquitin-like domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.786
ENSPNYP00000005212	polr2f	ENSPNYP00000005212	ENSPNYP00000026231	Ubiquitin-like domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide F.	0.863
ENSPNYP00000005212	polr2g	ENSPNYP00000005212	ENSPNYP00000021358	Ubiquitin-like domain-containing protein.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.640