109 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102199716	Proteasome subunit beta 12. (217 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
	ENSPNYP00000031825	Proteasome 26S subunit, non-ATPase 10. (138 aa)
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (396 aa)
	cdc6	Cell division cycle 6 homolog (S. cerevisiae). (434 aa)
	psma6	Proteasome subunit alpha type. (246 aa)
	mcm2	DNA helicase; Belongs to the MCM family. (886 aa)
	orc4	Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
	psmc4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
	psme2	Proteasome activator subunit 2. (245 aa)
	psmc1	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
	LOC102199978	Proteasome subunit alpha type. (246 aa)
	fam89a	Family with sequence similarity 89 member A. (180 aa)
	ENSPNYP00000028654	Uncharacterized protein. (295 aa)
	psmd1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (951 aa)
	anapc16	Anaphase promoting complex subunit 16. (108 aa)
	mcm3	DNA helicase; Belongs to the MCM family. (815 aa)
	LOC102205179	Fizzy/cell division cycle 20 related 1b. (487 aa)
	orc3	Origin recognition complex, subunit 3. (705 aa)
	ccne1	Cyclin E1; Belongs to the cyclin family. (432 aa)
	rps27a	Ribosomal protein S27a. (188 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	ENSPNYP00000000172	ANK_REP_REGION domain-containing protein. (102 aa)
	ENSPNYP00000000493	Uncharacterized protein. (80 aa)
	psmd14	Proteasome 26S subunit, non-ATPase 14. (310 aa)
	LOC102203116	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa)
	LOC102203678	Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (250 aa)
	LOC102207116	Cyclin A2; Belongs to the cyclin family. (440 aa)
	LOC102209997	Proteasome 26S subunit, non-ATPase 11b. (422 aa)
	psmd6	Proteasome 26S subunit, non-ATPase 6. (392 aa)
	LOC102205503	Proteasome subunit alpha type. (248 aa)
	psmd13	Proteasome 26S subunit, non-ATPase 13. (378 aa)
	psme3	Proteasome activator subunit 3. (256 aa)
	anapc5	Anaphase promoting complex subunit 5. (721 aa)
	ube2s	Ubiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (233 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	psmb2	Proteasome subunit beta. (199 aa)
	LOC102214802	Proteasome activator subunit 4b. (1804 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	psmb3	Proteasome subunit beta. (205 aa)
	mcm8	Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (838 aa)
	FZR1	Fizzy/cell division cycle 20 related 1a. (492 aa)
	LOC102205309	Proteasome subunit beta. (278 aa)
	mcm7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (723 aa)
	anapc10	Anaphase promoting complex subunit 10. (136 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	bicra	BRD4 interacting chromatin remodeling complex associated protein. (1776 aa)
	psmd8	Proteasome 26S subunit, non-ATPase 8. (265 aa)
	cdc26	Cell division cycle 26 homolog. (97 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (486 aa)
	LOC102199700	WD_REPEATS_REGION domain-containing protein. (489 aa)
	psma3	Proteasome subunit alpha type. (255 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (752 aa)
	LOC102203937	Proteasome 26S subunit, non-ATPase 4a. (377 aa)
	anapc1	Anaphase promoting complex subunit 1. (1872 aa)
	psma4	Proteasome subunit alpha type. (261 aa)
	psmc5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (407 aa)
	psma1	Proteasome subunit alpha type. (263 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
	gmnn	Geminin DNA replication inhibitor. (208 aa)
	anapc4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (780 aa)
	psmb8	Proteasome subunit beta. (279 aa)
	LOC102199990	Proteasome subunit beta. (275 aa)
	LOC102200259	Proteasome subunit beta. (216 aa)
	LOC102212057	Proteasome subunit beta11b. (362 aa)
	LOC102210455	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
	LOC102210761	Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	psme1	Proteasome activator subunit 1. (301 aa)
	psma8	Proteasome subunit alpha type. (251 aa)
	anapc15	Anaphase promoting complex subunit 15. (122 aa)
	ccna1	Cyclin A1; Belongs to the cyclin family. (389 aa)
	ENSPNYP00000017722	Cullin 1b; Belongs to the cullin family. (370 aa)
	psma2	Proteasome subunit alpha type. (234 aa)
	psmd9	Proteasome 26S subunit, non-ATPase 9. (212 aa)
	tm7sf3	Transmembrane 7 superfamily member 3. (554 aa)
	ube2c	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
	psmc6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
	mcm4	DNA helicase; Belongs to the MCM family. (860 aa)
	ENSPNYP00000020122	Uncharacterized protein. (133 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
	LOC102197382	Proteasome subunit beta 6. (221 aa)
	LOC102195846	Cyclin E2; Belongs to the cyclin family. (380 aa)
	cdc27	Cell division cycle 27. (833 aa)
	uba52	Ubiquitin-like domain-containing protein. (128 aa)
	mcm6	DNA helicase; Belongs to the MCM family. (825 aa)
	psmc3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
	psmb1	Proteasome subunit beta. (237 aa)
	orc2	Origin recognition complex, subunit 2. (429 aa)
	orc5	Origin recognition complex, subunit 5. (404 aa)
	LOC106456278	Ubiquitin-like domain-containing protein. (122 aa)
	psma5	Proteasome subunit alpha type. (241 aa)
	psmd3	Proteasome 26S subunit, non-ATPase 3. (562 aa)
	psmd12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	psmc2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
	psme4	Proteasome activator subunit 4a. (1847 aa)
	PSMD11	PCI domain-containing protein. (422 aa)
	ENSPNYP00000025540	Proteasome subunit beta. (288 aa)
	LOC102196183	Proteasome subunit beta. (281 aa)
	ENSPNYP00000004124	Proteasome inhibitor subunit 1. (236 aa)
	psmd7	Proteasome 26S subunit, non-ATPase 7. (332 aa)
	ENSPNYP00000005212	Ubiquitin-like domain-containing protein. (114 aa)
	psmd5	Proteasome 26S subunit, non-ATPase 5. (504 aa)
	bicral	BRD4 interacting chromatin remodeling complex associated protein like. (520 aa)
	orc1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (783 aa)
	LOC102207966	Proteasome 26S subunit, non-ATPase 4b. (375 aa)
	psmb7	Proteasome subunit beta. (286 aa)
	psmb4	Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
	ENSPNYP00000007911	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (300 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000000172	ENSPNYP00000005212	ENSPNYP00000000172	ENSPNYP00000005212	ANK_REP_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.482
ENSPNYP00000000172	ENSPNYP00000007911	ENSPNYP00000000172	ENSPNYP00000007911	ANK_REP_REGION domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.497
ENSPNYP00000000172	ENSPNYP00000017722	ENSPNYP00000000172	ENSPNYP00000017722	ANK_REP_REGION domain-containing protein.	Cullin 1b; Belongs to the cullin family.	0.640
ENSPNYP00000000172	ENSPNYP00000028654	ENSPNYP00000000172	ENSPNYP00000028654	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.920
ENSPNYP00000000172	FZR1	ENSPNYP00000000172	ENSPNYP00000009177	ANK_REP_REGION domain-containing protein.	Fizzy/cell division cycle 20 related 1a.	0.465
ENSPNYP00000000172	LOC102199700	ENSPNYP00000000172	ENSPNYP00000011086	ANK_REP_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.465
ENSPNYP00000000172	LOC102199978	ENSPNYP00000000172	ENSPNYP00000029212	ANK_REP_REGION domain-containing protein.	Proteasome subunit alpha type.	0.443
ENSPNYP00000000172	LOC102203116	ENSPNYP00000000172	ENSPNYP00000001003	ANK_REP_REGION domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.419
ENSPNYP00000000172	LOC102203678	ENSPNYP00000000172	ENSPNYP00000001044	ANK_REP_REGION domain-containing protein.	Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family.	0.419
ENSPNYP00000000172	LOC102203937	ENSPNYP00000000172	ENSPNYP00000013148	ANK_REP_REGION domain-containing protein.	Proteasome 26S subunit, non-ATPase 4a.	0.923
ENSPNYP00000000172	LOC102205179	ENSPNYP00000000172	ENSPNYP00000027972	ANK_REP_REGION domain-containing protein.	Fizzy/cell division cycle 20 related 1b.	0.465
ENSPNYP00000000172	LOC102205503	ENSPNYP00000000172	ENSPNYP00000001971	ANK_REP_REGION domain-containing protein.	Proteasome subunit alpha type.	0.443
ENSPNYP00000000172	LOC102207966	ENSPNYP00000000172	ENSPNYP00000007426	ANK_REP_REGION domain-containing protein.	Proteasome 26S subunit, non-ATPase 4b.	0.923
ENSPNYP00000000172	LOC102209997	ENSPNYP00000000172	ENSPNYP00000001492	ANK_REP_REGION domain-containing protein.	Proteasome 26S subunit, non-ATPase 11b.	0.921
ENSPNYP00000000172	LOC102210455	ENSPNYP00000000172	ENSPNYP00000016554	ANK_REP_REGION domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.419
ENSPNYP00000000172	LOC102210761	ENSPNYP00000000172	ENSPNYP00000016572	ANK_REP_REGION domain-containing protein.	Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family.	0.419
ENSPNYP00000000172	LOC106456278	ENSPNYP00000000172	ENSPNYP00000023328	ANK_REP_REGION domain-containing protein.	Ubiquitin-like domain-containing protein.	0.482
ENSPNYP00000000172	PSMD11	ENSPNYP00000000172	ENSPNYP00000025506	ANK_REP_REGION domain-containing protein.	PCI domain-containing protein.	0.921
ENSPNYP00000000172	anapc1	ENSPNYP00000000172	ENSPNYP00000013472	ANK_REP_REGION domain-containing protein.	Anaphase promoting complex subunit 1.	0.520
ENSPNYP00000000172	anapc10	ENSPNYP00000000172	ENSPNYP00000010099	ANK_REP_REGION domain-containing protein.	Anaphase promoting complex subunit 10.	0.458