STRINGSTRING
LOC102206140 LOC102206140 LOC102214279 LOC102214279 LOC102205634 LOC102205634 ENSPNYP00000003627 ENSPNYP00000003627 stard5 stard5 LOC102195127 LOC102195127 ebpl ebpl sqle sqle LOC102210419 LOC102210419 LOC102195009 LOC102195009 cubn cubn ENSPNYP00000005803 ENSPNYP00000005803 rusc1 rusc1 fdps fdps acot8 acot8 LOC102196680 LOC102196680 LOC102215893 LOC102215893 LOC102203806 LOC102203806 LOC102212771 LOC102212771 ncoa2 ncoa2 LOC102201505 LOC102201505 LOC102212044 LOC102212044 mbtps2 mbtps2 LOC102207357 LOC102207357 LOC102193520 LOC102193520 LOC102204900 LOC102204900 SLCO1C1 SLCO1C1 osbpl7 osbpl7 ENSPNYP00000000995 ENSPNYP00000000995 LOC102193348 LOC102193348 sdr16c5 sdr16c5 slc10a1 slc10a1 sugct sugct LOC102208737 LOC102208737 nsdhl nsdhl nfya nfya LOC102207172 LOC102207172 LOC102193812 LOC102193812 LOC102209583 LOC102209583 LOC102199547 LOC102199547 hmgcr hmgcr amacr amacr hsd3b1 hsd3b1 fdxr fdxr ENSPNYP00000008442 ENSPNYP00000008442 LOC102213271 LOC102213271 LOC102203001 LOC102203001 insig1 insig1 LOC102203607 LOC102203607 cdcp2 cdcp2 ptgis ptgis LOC102206997 LOC102206997 AKR1D1 AKR1D1 plpp6 plpp6 osbpl9 osbpl9 LOC102197346 LOC102197346 LOC102193239 LOC102193239 LOC102193524 LOC102193524 faxdc2 faxdc2 dhrs7c dhrs7c LOC102209021 LOC102209021 plpp7 plpp7 osbpl6 osbpl6 fdft1 fdft1 dhcr24 dhcr24 FDX1 FDX1 LOC102196938 LOC102196938 LOC102195116 LOC102195116 ENSPNYP00000012998 ENSPNYP00000012998 ENSPNYP00000013038 ENSPNYP00000013038 mbtps1 mbtps1 hsd17b1 hsd17b1 nfyc nfyc LOC102210029 LOC102210029 LOC102192919 LOC102192919 sdr42e1 sdr42e1 lbr lbr sc5d sc5d srd5a1 srd5a1 LOC102205438 LOC102205438 srd5a3 srd5a3 LOC102196214 LOC102196214 LOC102203810 LOC102203810 LOC102213235 LOC102213235 LOC102206105 LOC102206105 hsdl2 hsdl2 LOC102208884 LOC102208884 LOC102199200 LOC102199200 ENSPNYP00000015458 ENSPNYP00000015458 stard3 stard3 lss lss LOC102212757 LOC102212757 LOC102197872 LOC102197872 OSBPL1A OSBPL1A scap scap LOC102198140 LOC102198140 LOC102205918 LOC102205918 nr1h4 nr1h4 LOC102197279 LOC102197279 LOC102208803 LOC102208803 LOC102214484 LOC102214484 mtf1 mtf1 ggps1 ggps1 LOC102214289 LOC102214289 hsd3b7 hsd3b7 pmvk pmvk LOC102201298 LOC102201298 LOC102200964 LOC102200964 LOC102201877 LOC102201877 LOC102209452 LOC102209452 LOC102206724 LOC102206724 msmo1 msmo1 srd5a2 srd5a2 LOC102211083 LOC102211083 osbp2 osbp2 LOC102216220 LOC102216220 hsd17b3 hsd17b3 LOC102203776 LOC102203776 LOC102198167 LOC102198167 LOC102209297 LOC102209297 LOC102212432 LOC102212432 LOC102207549 LOC102207549 mvd mvd LOC102202447 LOC102202447 hsd17b14 hsd17b14 LOC102213864 LOC102213864 mvk mvk ncoa1 ncoa1 ebp ebp ran ran ENSPNYP00000022218 ENSPNYP00000022218 ENSPNYP00000022250 ENSPNYP00000022250 dhcr7 dhcr7 srebf1 srebf1 pias4 pias4 hsd17b4 hsd17b4 ch25h ch25h ube2i ube2i hsd11b1l hsd11b1l LOC102193155 LOC102193155 kpnb1 kpnb1 LOC102204834 LOC102204834 ENSPNYP00000023708 ENSPNYP00000023708 LOC102200640 LOC102200640 LOC102192968 LOC102192968 LOC102212740 LOC102212740 star star LOC102209912 LOC102209912 LOC102200667 LOC102200667 LOC102210873 LOC102210873 ENSPNYP00000025380 ENSPNYP00000025380 LOC102204113 LOC102204113 LOC102198437 LOC102198437 tspo tspo ENSPNYP00000026295 ENSPNYP00000026295 rimbp2 rimbp2 adgrd1 adgrd1 CYP19A1 CYP19A1 fabp6 fabp6 FADS6 FADS6 nfyb nfyb srebf2 srebf2 LOC102210256 LOC102210256 LOC102196187 LOC102196187 LOC102203466 LOC102203466 LOC102197929 LOC102197929 LOC102215951 LOC102215951 LOC102194145 LOC102194145 LOC102208223 LOC102208223 LOC102198498 LOC102198498 LOC102204648 LOC102204648 hsdl1 hsdl1 arv1 arv1 podn podn SERPINA4 SERPINA4 ENSPNYP00000029383 ENSPNYP00000029383 LOC102206432 LOC102206432 LOC102201915 LOC102201915 ENSPNYP00000029684 ENSPNYP00000029684 insig2 insig2 tm7sf2 tm7sf2 LOC102211303 LOC102211303 POMC POMC fdx2 fdx2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102206140Uncharacterized protein. (245 aa)
LOC102214279Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (516 aa)
LOC102205634Solute carrier family 10 member 1. (361 aa)
ENSPNYP00000003627Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (435 aa)
stard5StAR-related lipid transfer (START) domain containing 5. (228 aa)
LOC102195127PH domain-containing protein. (861 aa)
ebplEBP like. (223 aa)
sqleSqualene epoxidase a. (571 aa)
LOC102210419Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (630 aa)
LOC102195009Si:ch211-105f12.2. (220 aa)
cubnCubilin (intrinsic factor-cobalamin receptor). (3496 aa)
ENSPNYP00000005803CUB domain-containing protein. (110 aa)
rusc1RUN and SH3 domain containing 1. (524 aa)
fdpsUncharacterized protein; Belongs to the FPP/GGPP synthase family. (397 aa)
acot8Acyl-CoA thioesterase 8. (343 aa)
LOC102196680Solute carrier organic anion transporter family member. (732 aa)
LOC102215893Solute carrier organic anion transporter family member. (682 aa)
LOC102203806Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (531 aa)
LOC102212771Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
ncoa2Nuclear receptor coactivator 2. (1539 aa)
LOC102201505Uncharacterized protein. (416 aa)
LOC102212044Uncharacterized protein. (415 aa)
mbtps2Membrane-bound transcription factor peptidase, site 2. (502 aa)
LOC102207357Small ubiquitin-related modifier. (94 aa)
LOC102193520Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (547 aa)
LOC102204900acidPPc domain-containing protein. (259 aa)
SLCO1C1Solute carrier organic anion transporter family member. (659 aa)
osbpl7Oxysterol-binding protein; Belongs to the OSBP family. (844 aa)
ENSPNYP00000000995Aldo_ket_red domain-containing protein. (186 aa)
LOC102193348Cytochrome P450, family 7, subfamily A, polypeptide 1. (519 aa)
sdr16c5Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
slc10a1Solute carrier family 10 member 1. (349 aa)
sugctSuccinyl-CoA:glutarate-CoA transferase. (410 aa)
LOC102208737Solute carrier family 51 alpha subunit. (338 aa)
nsdhlNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (345 aa)
nfyaNuclear transcription factor Y, alpha, like. (346 aa)
LOC1022071723-hydroxy-3-methylglutaryl coenzyme A reductase. (871 aa)
LOC102193812Oxysterol-binding protein; Belongs to the OSBP family. (663 aa)
LOC102209583Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family. (299 aa)
LOC102199547Vitamin D receptor b. (425 aa)
hmgcr3-hydroxy-3-methylglutaryl coenzyme A reductase. (882 aa)
amacrAlpha-methylacyl-CoA racemase. (382 aa)
hsd3b1Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (374 aa)
fdxrNADPH:adrenodoxin oxidoreductase, mitochondrial. (494 aa)
ENSPNYP00000008442Aldo_ket_red domain-containing protein. (199 aa)
LOC102213271Cytochrome P450, family 24, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (513 aa)
LOC102203001Retinol dehydrogenase 8b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (276 aa)
LOC1022036073-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (525 aa)
cdcp2CUB domain containing protein 2. (390 aa)
ptgisUncharacterized protein; Belongs to the cytochrome P450 family. (484 aa)
LOC102206997Zgc:56622. (326 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (354 aa)
plpp6Phospholipid phosphatase 6. (286 aa)
osbpl9Oxysterol-binding protein; Belongs to the OSBP family. (755 aa)
LOC102197346Cytochrome P450, family 2, subfamily R, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
LOC102193239Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (316 aa)
LOC102193524Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1. (303 aa)
faxdc2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (420 aa)
dhrs7cDehydrogenase/reductase (SDR family) member 7Cb. (313 aa)
LOC102209021Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. (266 aa)
plpp7Phospholipid phosphatase 7 (inactive). (287 aa)
osbpl6Oxysterol-binding protein; Belongs to the OSBP family. (783 aa)
fdft1Farnesyl-diphosphate farnesyltransferase 1. (487 aa)
dhcr2424-dehydrocholesterol reductase. (516 aa)
FDX1Ferredoxin 1. (162 aa)
LOC102196938Cytochrome P450, family 51; Belongs to the cytochrome P450 family. (499 aa)
LOC102195116Uncharacterized protein. (217 aa)
ENSPNYP00000012998Oxysterol-binding protein; Belongs to the OSBP family. (488 aa)
ENSPNYP00000013038ANK_REP_REGION domain-containing protein. (104 aa)
mbtps1Membrane-bound transcription factor peptidase, site 1. (1083 aa)
hsd17b1Hydroxysteroid (17-beta) dehydrogenase 1. (289 aa)
nfycNuclear transcription factor Y, gamma. (356 aa)
LOC102210029Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
LOC102192919Uncharacterized protein. (437 aa)
sdr42e1Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family. (386 aa)
lbrLamin B receptor. (622 aa)
sc5dSterol-C5-desaturase; Belongs to the sterol desaturase family. (302 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (244 aa)
LOC102205438Oxysterol-binding protein; Belongs to the OSBP family. (759 aa)
srd5a3Steroid 5 alpha-reductase 3. (344 aa)
LOC102196214Acyl-CoA thioesterase 19. (435 aa)
LOC102203810Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family. (277 aa)
LOC102213235Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family. (506 aa)
LOC102206105Uncharacterized protein. (306 aa)
hsdl2Hydroxysteroid dehydrogenase like 2. (419 aa)
LOC102208884Oxysterol-binding protein; Belongs to the OSBP family. (472 aa)
LOC102199200Luteinizing hormone, beta polypeptide. (155 aa)
ENSPNYP00000015458Uncharacterized protein. (94 aa)
stard3StAR-related lipid transfer (START) domain containing 3. (454 aa)
lssTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (689 aa)
LOC102212757Si:dkey-91i10.3; Belongs to the cytochrome P450 family. (542 aa)
LOC102197872Cytochrome P450, family 27, subfamily A, polypeptide 7. (439 aa)
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (908 aa)
scapSREBF chaperone. (1271 aa)
LOC102198140Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (533 aa)
LOC102205918Nuclear receptor coactivator. (1465 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (485 aa)
LOC102197279Oxysterol-binding protein; Belongs to the OSBP family. (391 aa)
LOC102208803Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (530 aa)
LOC102214484Uncharacterized protein. (1005 aa)
mtf1Metal-regulatory transcription factor 1. (796 aa)
ggps1Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (315 aa)
LOC102214289acidPPc domain-containing protein. (297 aa)
hsd3b7Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family. (366 aa)
pmvkPhosphomevalonate kinase. (200 aa)
LOC102201298Retinol dehydrogenase 8a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (342 aa)
LOC102200964Uncharacterized protein. (325 aa)
LOC102201877Zmp:0000001048; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (308 aa)
LOC102209452Nuclear receptor subfamily 1, group H, member 5. (515 aa)
LOC102206724Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family. (467 aa)
msmo1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (291 aa)
srd5a23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (251 aa)
LOC102211083Oxysterol-binding protein; Belongs to the OSBP family. (787 aa)
osbp2Oxysterol-binding protein; Belongs to the OSBP family. (735 aa)
LOC102216220Uncharacterized protein. (420 aa)
hsd17b3Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
LOC102203776Small ubiquitin-related modifier. (94 aa)
LOC102198167Oxysterol-binding protein; Belongs to the OSBP family. (789 aa)
LOC102209297Solute carrier organic anion transporter family member. (684 aa)
LOC102212432Small ubiquitin-related modifier. (96 aa)
LOC102207549Cytochrome P450, family 8, subfamily B, polypeptide 2; Belongs to the cytochrome P450 family. (511 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
LOC1022024473-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (249 aa)
hsd17b14Hydroxysteroid (17-beta) dehydrogenase 14. (289 aa)
LOC102213864Uncharacterized protein. (422 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
ncoa1Nuclear receptor coactivator 1. (1481 aa)
ebpEBP cholestenol delta-isomerase. (228 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (215 aa)
ENSPNYP00000022218Uncharacterized protein. (669 aa)
ENSPNYP00000022250Uncharacterized protein. (1334 aa)
dhcr77-dehydrocholesterol reductase. (472 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1174 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
hsd17b4Hydroxysteroid (17-beta) dehydrogenase 4. (737 aa)
ch25hCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (214 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
hsd11b1lHydroxysteroid (11-beta) dehydrogenase 1-like a. (286 aa)
LOC102193155Hydroxysteroid (11-beta) dehydrogenase 1-like a. (287 aa)
kpnb1Karyopherin (importin) beta 1. (916 aa)
LOC102204834Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (409 aa)
ENSPNYP00000023708AMP-binding domain-containing protein. (225 aa)
LOC102200640Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; Belongs to the serpin family. (404 aa)
LOC102192968Solute carrier family 27 member 2a. (742 aa)
LOC102212740UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
starSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
LOC102209912Uncharacterized protein. (620 aa)
LOC102200667Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
LOC102210873Retinoid X receptor, alpha a. (499 aa)
ENSPNYP00000025380Uncharacterized protein. (408 aa)
LOC102204113Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family. (280 aa)
LOC102198437Hydroxysteroid (17-beta) dehydrogenase 7. (340 aa)
tspoTranslocator protein. (161 aa)
ENSPNYP00000026295Uncharacterized protein. (147 aa)
rimbp2RIMS binding protein 2. (1018 aa)
adgrd1Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (815 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (483 aa)
fabp6Fatty acid binding protein 6, ileal (gastrotropin). (127 aa)
FADS6Fatty acid desaturase 6. (373 aa)
nfybNuclear transcription factor Y, beta a. (204 aa)
srebf2Sterol regulatory element binding transcription factor 2. (1012 aa)
LOC102210256Cytochrome P450, family 27, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (511 aa)
LOC102196187Uncharacterized protein. (345 aa)
LOC102203466Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (556 aa)
LOC102197929Oxysterol-binding protein; Belongs to the OSBP family. (771 aa)
LOC102215951Si:ch211-113j14.1; Belongs to the cytochrome P450 family. (525 aa)
LOC102194145START domain-containing protein. (218 aa)
LOC102208223AMP-binding domain-containing protein. (665 aa)
LOC102198498Zgc:109982; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
LOC102204648Uncharacterized protein. (204 aa)
hsdl1Hydroxysteroid dehydrogenase like 1. (325 aa)
arv1ARV1 homolog, fatty acid homeostasis modulator. (239 aa)
podnPodocan. (586 aa)
SERPINA4Serpin family A member 4; Belongs to the serpin family. (445 aa)
ENSPNYP00000029383Uncharacterized protein. (341 aa)
LOC102206432Cytochrome P450 family 46 subfamily A member 1. (510 aa)
LOC102201915Acyl-CoA thioesterase 21. (439 aa)
ENSPNYP00000029684Uncharacterized protein. (197 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (241 aa)
tm7sf2Transmembrane 7 superfamily member 2. (425 aa)
LOC102211303Probable lipid phosphate phosphatase PPAPDC3. (287 aa)
POMCProopiomelanocortin. (201 aa)
fdx2Ferredoxin 2. (180 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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