(65 nodes) Fructose and mannose metabolism network (Pundamilia nyererei)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102208961	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (279 aa)
	etfbkmt	Electron transfer flavoprotein subunit beta lysine methyltransferase. (258 aa)
	pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (457 aa)
	LOC102194427	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	lmcd1	LIM and cysteine-rich domains 1. (369 aa)
	tsta3	Tissue specific transplantation antigen P35B. (318 aa)
	ENSPNYP00000030255	GDP-mannose 4,6-dehydratase. (385 aa)
	tpi1	Triosephosphate isomerase. (247 aa)
	vcpkmt	Valosin containing protein lysine (K) methyltransferase. (248 aa)
	LOC102204587	Triosephosphate isomerase. (184 aa)
	pmm1	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (261 aa)
	LOC102206595	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (783 aa)
	pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b. (544 aa)
	NIPAL2	NIPA like domain containing 2. (313 aa)
	LOC102207128	NIPA like domain containing 4. (393 aa)
	trmt1l	tRNA (guanine(26)-N(2))-dimethyltransferase. (619 aa)
	ENSPNYP00000007473	FBPase domain-containing protein. (145 aa)
	LOC102202425	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b. (496 aa)
	LOC102206163	6PF2K domain-containing protein. (472 aa)
	LOC102201923	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (771 aa)
	LOC102212192	TNNI3 interacting kinase. (813 aa)
	fpgt	Fucose-1-phosphate guanylyltransferase. (564 aa)
	tkfc	Triokinase/FMN cyclase. (583 aa)
	sord	Sorbitol dehydrogenase. (354 aa)
	LOC102193239	Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (316 aa)
	LOC102193524	Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1. (303 aa)
	LOC102211819	Hexokinase 2. (873 aa)
	LOC102198838	Zgc:101583. (358 aa)
	wrap73	WD repeat containing, antisense to TP73. (449 aa)
	mettl21a	Methyltransferase like 21A. (230 aa)
	mpi	Mannose phosphate isomerase. (368 aa)
	fuom	Fucose mutarotase. (154 aa)
	mettl23	Methyltransferase like 23. (242 aa)
	gmppb	GDP-mannose pyrophosphorylase B. (360 aa)
	ENSPNYP00000017762	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (779 aa)
	trmt1	tRNA (guanine(26)-N(2))-dimethyltransferase. (599 aa)
	LOC102213522	Phosphotransferase. (491 aa)
	khk	Ketohexokinase. (333 aa)
	ENSPNYP00000019354	Uncharacterized protein. (253 aa)
	pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (525 aa)
	LOC102195213	Hexokinase domain containing 1. (925 aa)
	LOC102205904	Hexokinase 1. (918 aa)
	gmppa	GDP-mannose pyrophosphorylase Ab. (436 aa)
	LOC102207370	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	LOC102200373	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family. (337 aa)
	LOC102203213	Zgc:92518. (256 aa)
	LOC102202928	Uncharacterized protein. (577 aa)
	LOC102200703	Triosephosphate isomerase. (248 aa)
	LOC102200931	Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (250 aa)
	LOC102206918	Uncharacterized protein. (923 aa)
	enosf1	Enolase superfamily member 1. (472 aa)
	ENSPNYP00000005023	FBPase domain-containing protein. (57 aa)
	LOC102202902	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (337 aa)
	pfkl	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (781 aa)
	fcsk	Fucose kinase. (925 aa)
	LOC102198082	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	ENSPNYP00000022617	Uncharacterized protein. (169 aa)
	LOC102197026	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	nipal4	NIPA magnesium transporter 2. (440 aa)
	nipa1	NIPA magnesium transporter 1. (329 aa)
	nipal3	NIPA like domain containing 3. (383 aa)
	LOC102204582	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a. (543 aa)
	EEF1AKMT3	EEF1A lysine methyltransferase 3. (223 aa)
	LOC102210141	TP53 induced glycolysis regulatory phosphatase a. (271 aa)
	LOC102198836	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a. (467 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF1AKMT3	ENSPNYP00000005023	ENSPNYP00000025754	ENSPNYP00000005023	EEF1A lysine methyltransferase 3.	FBPase domain-containing protein.	0.486
EEF1AKMT3	ENSPNYP00000007473	ENSPNYP00000025754	ENSPNYP00000007473	EEF1A lysine methyltransferase 3.	FBPase domain-containing protein.	0.486
EEF1AKMT3	LOC102198836	ENSPNYP00000025754	ENSPNYP00000026458	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a.	0.525
EEF1AKMT3	LOC102200373	ENSPNYP00000025754	ENSPNYP00000005004	EEF1A lysine methyltransferase 3.	Fructose-1,6-bisphosphatase 2; Belongs to the FBPase class 1 family.	0.486
EEF1AKMT3	LOC102202425	ENSPNYP00000025754	ENSPNYP00000007727	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b.	0.525
EEF1AKMT3	LOC102202902	ENSPNYP00000025754	ENSPNYP00000001125	EEF1A lysine methyltransferase 3.	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	0.486
EEF1AKMT3	LOC102204582	ENSPNYP00000025754	ENSPNYP00000024753	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a.	0.525
EEF1AKMT3	LOC102206163	ENSPNYP00000025754	ENSPNYP00000007798	EEF1A lysine methyltransferase 3.	6PF2K domain-containing protein.	0.525
EEF1AKMT3	pfkfb1	ENSPNYP00000025754	ENSPNYP00000029243	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	0.525
EEF1AKMT3	pfkfb2	ENSPNYP00000025754	ENSPNYP00000005446	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b.	0.525
EEF1AKMT3	pfkfb3	ENSPNYP00000025754	ENSPNYP00000020158	EEF1A lysine methyltransferase 3.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3.	0.525
ENSPNYP00000005023	EEF1AKMT3	ENSPNYP00000005023	ENSPNYP00000025754	FBPase domain-containing protein.	EEF1A lysine methyltransferase 3.	0.486
ENSPNYP00000005023	ENSPNYP00000017762	ENSPNYP00000005023	ENSPNYP00000017762	FBPase domain-containing protein.	6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.	0.718
ENSPNYP00000005023	ENSPNYP00000019354	ENSPNYP00000005023	ENSPNYP00000019354	FBPase domain-containing protein.	Uncharacterized protein.	0.485
ENSPNYP00000005023	ENSPNYP00000022617	ENSPNYP00000005023	ENSPNYP00000022617	FBPase domain-containing protein.	Uncharacterized protein.	0.834
ENSPNYP00000005023	LOC102194427	ENSPNYP00000005023	ENSPNYP00000029603	FBPase domain-containing protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.757
ENSPNYP00000005023	LOC102195213	ENSPNYP00000005023	ENSPNYP00000021077	FBPase domain-containing protein.	Hexokinase domain containing 1.	0.840
ENSPNYP00000005023	LOC102197026	ENSPNYP00000005023	ENSPNYP00000022644	FBPase domain-containing protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.875
ENSPNYP00000005023	LOC102198082	ENSPNYP00000005023	ENSPNYP00000000847	FBPase domain-containing protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.875
ENSPNYP00000005023	LOC102198836	ENSPNYP00000005023	ENSPNYP00000026458	FBPase domain-containing protein.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a.	0.821