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GOT1 GOT1 mri1 mri1 apip apip LOC102209111 LOC102209111 kyat1 kyat1 mat2b mat2b adi1 adi1 LOC102200292 LOC102200292 psat1 psat1 LOC102210314 LOC102210314 trdmt1 trdmt1 tstd3 tstd3 LOC102198260 LOC102198260 ENSPNYP00000005668 ENSPNYP00000005668 bcat1 bcat1 LOC102202437 LOC102202437 enoph1 enoph1 ENSPNYP00000006841 ENSPNYP00000006841 ahcyl1 ahcyl1 phgdh phgdh LOC102215772 LOC102215772 AHCYL2 AHCYL2 LOC102202810 LOC102202810 tfb1m tfb1m srm srm tat tat LOC102208245 LOC102208245 LOC102207963 LOC102207963 AHCYL1 AHCYL1 mpst mpst ENSPNYP00000010053 ENSPNYP00000010053 ENSPNYP00000010100 ENSPNYP00000010100 got1 got1 scube2 scube2 LOC102201327 LOC102201327 LOC102214571 LOC102214571 mtap mtap srfbp1 srfbp1 amd1 amd1 LOC102202693 LOC102202693 ahcy ahcy ENSPNYP00000015093 ENSPNYP00000015093 mfsd11 mfsd11 dnmt1 dnmt1 LOC102192203 LOC102192203 ENSPNYP00000018607 ENSPNYP00000018607 sms sms lto1 lto1 LOC102202914 LOC102202914 LOC102200769 LOC102200769 got2 got2 LOC102208802 LOC102208802 LOC102208556 LOC102208556 LOC102207766 LOC102207766 LOC102209116 LOC102209116 LOC102212612 LOC102212612 hsd17b14 hsd17b14 LOC102211461 LOC102211461 mdh1b mdh1b SDS SDS tfb2m tfb2m ENSPNYP00000023391 ENSPNYP00000023391 LOC102193980 LOC102193980 ENSPNYP00000023623 ENSPNYP00000023623 LOC102212451 LOC102212451 mdh1 mdh1 scube3 scube3 LOC102201204 LOC102201204 mtr mtr vbp1 vbp1 dimt1 dimt1 LOC102202920 LOC102202920 ENSPNYP00000026001 ENSPNYP00000026001 scube1 scube1 LOC102193728 LOC102193728 gclc gclc LOC102191994 LOC102191994 gclm gclm cth cth LOC102210540 LOC102210540 LOC102192167 LOC102192167 fam114a1 fam114a1 LOC102201214 LOC102201214 ENSPNYP00000031616 ENSPNYP00000031616 LOC102205506 LOC102205506
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GOT1Aspartate aminotransferase. (410 aa)
mri1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (353 aa)
apipMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis. (245 aa)
LOC102209111AdoHcyase_NAD domain-containing protein. (483 aa)
kyat1Kynurenine aminotransferase 1. (445 aa)
mat2bMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (336 aa)
adi11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
LOC102200292DNA (cytosine-5-)-methyltransferase 3 alpha b; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (979 aa)
psat1Phosphoserine aminotransferase. (368 aa)
LOC102210314L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (355 aa)
trdmt1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (382 aa)
tstd3Si:dkey-165n16.1. (173 aa)
LOC102198260Serine dehydratase-like. (322 aa)
ENSPNYP00000005668Si:ch211-161h7.8. (111 aa)
bcat1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (366 aa)
LOC102202437S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
enoph1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
ENSPNYP00000006841Uncharacterized protein. (141 aa)
ahcyl1Adenosylhomocysteinase-like 1; Belongs to the adenosylhomocysteinase family. (504 aa)
phgdhPhosphoglycerate dehydrogenase. (506 aa)
LOC102215772Betaine-homocysteine methyltransferase; Involved in the regulation of homocysteine metabolism. (369 aa)
AHCYL2Adenosylhomocysteinase-like 2; Belongs to the adenosylhomocysteinase family. (601 aa)
LOC102202810S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (387 aa)
tfb1mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (360 aa)
srmSpermidine synthase; Belongs to the spermidine/spermine synthase family. (308 aa)
tatTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (479 aa)
LOC102208245Amine oxidase. (953 aa)
LOC102207963Amino_oxidase domain-containing protein. (493 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (550 aa)
mpstSulfurtransferase. (292 aa)
ENSPNYP00000010053Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (498 aa)
ENSPNYP00000010100Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (477 aa)
got1Aspartate aminotransferase. (410 aa)
scube2Signal peptide, CUB domain, EGF-like 2. (1020 aa)
LOC102201327Malate dehydrogenase. (333 aa)
LOC102214571Uncharacterized protein. (446 aa)
mtapS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (299 aa)
srfbp1BUD22 domain-containing protein. (536 aa)
amd1S-adenosylmethionine decarboxylase proenzyme. (336 aa)
LOC102202693S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (371 aa)
ahcyAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (433 aa)
ENSPNYP00000015093Malate dehydrogenase. (186 aa)
mfsd11Major facilitator superfamily domain containing 11. (454 aa)
dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1501 aa)
LOC102192203DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1432 aa)
ENSPNYP00000018607Amine oxidase. (540 aa)
smsSpermine synthase. (360 aa)
lto1LTO1 maturation factor of ABCE1. (141 aa)
LOC102202914S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
LOC1022007691-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional). (868 aa)
got2Aspartate aminotransferase. (428 aa)
LOC102208802L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
LOC102208556Rhodanese domain-containing protein. (119 aa)
LOC102207766Glutamic-oxaloacetic transaminase 1 like 1. (425 aa)
LOC102209116Rhodanese domain-containing protein. (119 aa)
LOC102212612L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
hsd17b14Hydroxysteroid (17-beta) dehydrogenase 14. (289 aa)
LOC102211461Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (390 aa)
mdh1bMalate dehydrogenase 1B, NAD (soluble). (468 aa)
SDSSerine dehydratase. (319 aa)
tfb2mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (453 aa)
ENSPNYP00000023391Cysteine dioxygenase. (168 aa)
LOC102193980Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. (397 aa)
ENSPNYP00000023623Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. (217 aa)
LOC102212451Sulfurtransferase. (300 aa)
mdh1Malate dehydrogenase. (333 aa)
scube3Signal peptide, CUB domain, EGF-like 3. (1016 aa)
LOC102201204Zgc:172121; Involved in the regulation of homocysteine metabolism. (333 aa)
mtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1269 aa)
vbp1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (195 aa)
dimt1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (306 aa)
LOC102202920Cystathionine-beta-synthase b. (570 aa)
ENSPNYP00000026001Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (573 aa)
scube1Signal peptide, CUB domain, EGF-like 1. (875 aa)
LOC102193728S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (393 aa)
gclcGlutamate-cysteine ligase, catalytic subunit. (630 aa)
LOC102191994Kynurenine aminotransferase 3. (449 aa)
gclmGlutamate-cysteine ligase, modifier subunit. (277 aa)
cthCystathionase (cystathionine gamma-lyase), like. (402 aa)
LOC102210540DNA (cytosine-5-)-methyltransferase 3 alpha a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (836 aa)
LOC102192167Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (576 aa)
fam114a1Family with sequence similarity 114 member A1. (599 aa)
LOC102201214Amine oxidase. (517 aa)
ENSPNYP00000031616DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1001 aa)
LOC102205506DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (785 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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