STRINGSTRING
pcna pcna ercc3 ercc3 xpa xpa LOC102213342 LOC102213342 lig1 lig1 CLSPN CLSPN atad5 atad5 cul4a cul4a ercc4 ercc4 pole3 pole3 cdk20 cdk20 ENSPNYP00000004552 ENSPNYP00000004552 ENSPNYP00000004582 ENSPNYP00000004582 LOC102196725 LOC102196725 sass6 sass6 rfc2 rfc2 fbxw12 fbxw12 pold4 pold4 rfc5 rfc5 LOC102194415 LOC102194415 ENSPNYP00000011207 ENSPNYP00000011207 pold1 pold1 ddx11 ddx11 ENSPNYP00000011626 ENSPNYP00000011626 rfc3 rfc3 gtf2h3 gtf2h3 ENSPNYP00000018622 ENSPNYP00000018622 rpa2 rpa2 ddb2 ddb2 rad23a rad23a fbh1 fbh1 gtf2h1 gtf2h1 pold3 pold3 LOC102215177 LOC102215177 LOC102209807 LOC102209807 pole pole pole2 pole2 pold2 pold2 stn1 stn1 bivm bivm cdk7 cdk7 ENSPNYP00000025590 ENSPNYP00000025590 ercc1 ercc1 LOC102204724 LOC102204724 ccnh ccnh meiob meiob pole4 pole4 prkrip1 prkrip1 ercc2 ercc2 mnat1 mnat1 znf609 znf609 rfc1 rfc1 rbx1 rbx1 RPA1 RPA1 LOC102203234 LOC102203234 cetn2 cetn2 ercc8 ercc8 cul4b cul4b ercc6 ercc6 gtf2h4 gtf2h4 LOC102208280 LOC102208280 xpc xpc rpa3 rpa3 LOC102200695 LOC102200695 chrac1 chrac1 rfc4 rfc4 gtf2h5 gtf2h5 yju2 yju2 shd shd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
xpaXeroderma pigmentosum, complementation group A. (271 aa)
LOC102213342Centrin 4. (185 aa)
lig1DNA ligase. (1012 aa)
CLSPNClaspin. (1146 aa)
atad5AAA domain-containing protein. (746 aa)
cul4aCullin 4A; Belongs to the cullin family. (692 aa)
ercc4Excision repair cross-complementation group 4. (886 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
cdk20Cyclin-dependent kinase 20. (323 aa)
ENSPNYP00000004552Excision repair cross-complementation group 5. (853 aa)
ENSPNYP00000004582XPGN domain-containing protein. (222 aa)
LOC102196725Uncharacterized protein. (471 aa)
sass6SAS-6 centriolar assembly protein. (521 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
fbxw12Si:ch73-142c19.1. (474 aa)
pold4Si:dkey-28b4.7. (107 aa)
rfc5Replication factor C (activator 1) 5. (342 aa)
LOC102194415Uncharacterized protein. (161 aa)
ENSPNYP00000011207Ubiquitin-like domain-containing protein. (128 aa)
pold1DNA polymerase. (1105 aa)
ddx11DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (892 aa)
ENSPNYP00000011626Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (294 aa)
ENSPNYP00000018622Uncharacterized protein. (967 aa)
rpa2Replication protein A2. (293 aa)
ddb2Damage-specific DNA binding protein 2. (490 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (396 aa)
fbh1F-box DNA helicase 1. (908 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (513 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (443 aa)
LOC102215177Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
LOC102209807Calcium binding protein 5a. (178 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2015 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (509 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)
bivmBasic, immunoglobulin-like variable motif containing. (496 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
ENSPNYP00000025590WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (305 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
LOC102204724General transcription factor IIH subunit. (392 aa)
ccnhCyclin H; Belongs to the cyclin family. (343 aa)
meiobMethionine sulfoxide reductase B1b. (456 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
prkrip1PRKR interacting protein 1. (193 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
znf609C2H2-type domain-containing protein. (1314 aa)
rfc1Replication factor C subunit 1. (1153 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (640 aa)
LOC102203234Damage-specific DNA binding protein 1. (573 aa)
cetn2Centrin, EF-hand protein, 2. (171 aa)
ercc8Excision repair cross-complementation group 8. (409 aa)
cul4bCullin 4B; Belongs to the cullin family. (865 aa)
ercc6Excision repair cross-complementation group 6. (1408 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
LOC102208280Damage-specific DNA binding protein 1. (562 aa)
xpcXeroderma pigmentosum, complementation group C. (892 aa)
rpa3Replication protein A3. (122 aa)
LOC102200695Zinc finger protein 609b. (1370 aa)
chrac1Chromatin accessibility complex subunit 1. (125 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
yju2YJU2 splicing factor homolog. (340 aa)
shdSrc homology 2 domain containing transforming protein D, a. (406 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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