STRINGSTRING
ENSPNYP00000027707 ENSPNYP00000027707 sos1 sos1 LOC102209716 LOC102209716 LOC102206396 LOC102206396 drd2 drd2 LOC102206406 LOC102206406 ENSPNYP00000023736 ENSPNYP00000023736 LOC102209269 LOC102209269 ENSPNYP00000008904 ENSPNYP00000008904 ENSPNYP00000008879 ENSPNYP00000008879 prkg1 prkg1 SRC SRC LOC102205644 LOC102205644 prkg2 prkg2 LOC102211711 LOC102211711 itpr3 itpr3 ENSPNYP00000007442 ENSPNYP00000007442 LOC102200199 LOC102200199 mapk1 mapk1 tubb4b tubb4b raf1 raf1 LOC102208604 LOC102208604 LOC102200228 LOC102200228 rrad rrad prkaca prkaca LOC102191962 LOC102191962 LOC102194177 LOC102194177 LOC102201288 LOC102201288 pdgfb pdgfb LOC102203222 LOC102203222 cdk1 cdk1 REM1 REM1 ENSPNYP00000003091 ENSPNYP00000003091 LOC102209690 LOC102209690 LOC102197760 LOC102197760 adrb1 adrb1 pdgfa pdgfa LOC102194125 LOC102194125 ENSPNYP00000001632 ENSPNYP00000001632 PLCB2 PLCB2 ADCY9 ADCY9 PLCB4 PLCB4 PLCB1 PLCB1 pdgfrb pdgfrb ENSPNYP00000000232 ENSPNYP00000000232 LOC106455901 LOC106455901 adcy6 adcy6 egf egf tjp1 tjp1 map3k2 map3k2 grb2 grb2 plcb3 plcb3 LOC102192078 LOC102192078 pdgfc pdgfc LOC102200029 LOC102200029 htr2b htr2b LOC102212710 LOC102212710 LOC102203088 LOC102203088 LOC102205713 LOC102205713 LOC102211421 LOC102211421 ENSPNYP00000029644 ENSPNYP00000029644 ENSPNYP00000029651 ENSPNYP00000029651 tubb tubb LOC102203018 LOC102203018 prkacb prkacb ENSPNYP00000030353 ENSPNYP00000030353 ENSPNYP00000030592 ENSPNYP00000030592 LOC102195551 LOC102195551 ENSPNYP00000031399 ENSPNYP00000031399 LOC102210503 LOC102210503 gem gem prkca prkca egfr egfr LOC102206349 LOC102206349 PRKCB PRKCB ENSPNYP00000025478 ENSPNYP00000025478 ENSPNYP00000025611 ENSPNYP00000025611 ENSPNYP00000025623 ENSPNYP00000025623 ENSPNYP00000025641 ENSPNYP00000025641 LOC102210300 LOC102210300 LOC102211544 LOC102211544 htr2a htr2a LOC102200516 LOC102200516 ENSPNYP00000027112 ENSPNYP00000027112 mapk7 mapk7 LOC102193199 LOC102193199 LOC102213574 LOC102213574 map2k5 map2k5 LOC102202877 LOC102202877 LOC102200234 LOC102200234 LOC102198516 LOC102198516 gucy1b1 gucy1b1 ENSPNYP00000011447 ENSPNYP00000011447 ENSPNYP00000011458 ENSPNYP00000011458 LOC102210075 LOC102210075 TUBB TUBB LOC102208768 LOC102208768 CSNK1D CSNK1D sos2 sos2 adcy3 adcy3 lpar1 lpar1 ENSPNYP00000012665 ENSPNYP00000012665 LOC102192308 LOC102192308 LOC102194398 LOC102194398 adcy7 adcy7 LOC102207311 LOC102207311 adcy2 adcy2 LOC102209105 LOC102209105 pdgfra pdgfra GNAS GNAS LOC102200506 LOC102200506 LOC102201843 LOC102201843 adcy5 adcy5 LOC102213139 LOC102213139 LOC102201029 LOC102201029 LOC102212804 LOC102212804 LOC102213840 LOC102213840 ENSPNYP00000017487 ENSPNYP00000017487 LOC102192069 LOC102192069 LOC102202611 LOC102202611 LOC102205468 LOC102205468 itpr2 itpr2 CSDE1 CSDE1 KRAS KRAS map2k1 map2k1 ENSPNYP00000019127 ENSPNYP00000019127 LOC102192349 LOC102192349 grm5 grm5 LOC102197140 LOC102197140 pdgfd pdgfd LOC102211734 LOC102211734 GUCY1A2 GUCY1A2 hras hras GJA1 GJA1 LOC102197068 LOC102197068 ENSPNYP00000020486 ENSPNYP00000020486 adcy8 adcy8 GJD2 GJD2 map2k2 map2k2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPNYP00000027707Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (296 aa)
sos1Son of sevenless homolog 1 (Drosophila). (1166 aa)
LOC102209716Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
LOC102206396Uncharacterized protein. (354 aa)
drd2Dopamine receptor D2a; Belongs to the G-protein coupled receptor 1 family. (468 aa)
LOC102206406Uncharacterized protein; Belongs to the protein kinase superfamily. (446 aa)
ENSPNYP00000023736Cyclic nucleotide-binding domain-containing protein. (203 aa)
LOC102209269Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (623 aa)
ENSPNYP00000008904PH_14 domain-containing protein. (208 aa)
ENSPNYP00000008879Phosphoinositide phospholipase C. (437 aa)
prkg1cGMP-dependent protein kinase. (684 aa)
SRCTyrosine-protein kinase. (464 aa)
LOC102205644Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
prkg2cGMP-dependent protein kinase. (773 aa)
LOC102211711Uncharacterized protein. (374 aa)
itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2586 aa)
ENSPNYP00000007442Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (281 aa)
LOC102200199Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (334 aa)
tubb4bTubulin domain-containing protein. (125 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (672 aa)
LOC102208604Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (303 aa)
LOC102200228Tubulin domain-containing protein. (151 aa)
rradRas-related associated with diabetes. (309 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (343 aa)
LOC102191962Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1448 aa)
LOC102194177Mitogen-activated protein kinase kinase 2b. (395 aa)
LOC102201288Tight junction protein 1a; Belongs to the MAGUK family. (1678 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (548 aa)
LOC102203222Inositol 1,4,5-trisphosphate receptor, type 1b. (2693 aa)
cdk1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (276 aa)
REM1RRAD and GEM like GTPase 1. (301 aa)
ENSPNYP00000003091Protein kinase domain-containing protein. (69 aa)
LOC102209690Uncharacterized protein. (355 aa)
LOC102197760Guanine nucleotide binding protein (G protein) alpha v1. (361 aa)
adrb1Adrenoceptor beta 1. (397 aa)
pdgfaPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (230 aa)
LOC102194125Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
ENSPNYP00000001632Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (306 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1228 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1450 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1084 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1125 aa)
pdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1104 aa)
ENSPNYP00000000232Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (448 aa)
LOC106455901Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
egfEpidermal growth factor. (916 aa)
tjp1Tight junction protein 1b; Belongs to the MAGUK family. (1729 aa)
map3k2Mitogen-activated protein kinase kinase kinase 2. (647 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1243 aa)
LOC102192078Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (883 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (364 aa)
LOC102200029Inositol 1,4,5-trisphosphate receptor, type 1a. (2669 aa)
htr2b5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (478 aa)
LOC102212710Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC102203088Tyrosine-protein kinase. (537 aa)
LOC102205713Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
LOC102211421Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ENSPNYP00000029644Tubulin domain-containing protein. (87 aa)
ENSPNYP00000029651Tubulin domain-containing protein. (154 aa)
tubbTubulin domain-containing protein. (151 aa)
LOC102203018Casein kinase 1 delta; Belongs to the protein kinase superfamily. (404 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (381 aa)
ENSPNYP00000030353Tubulin domain-containing protein. (116 aa)
ENSPNYP00000030592G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (369 aa)
LOC102195551Glutamate receptor, metabotropic 5a. (1162 aa)
ENSPNYP00000031399Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (349 aa)
LOC102210503Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1120 aa)
gemGTP binding protein overexpressed in skeletal muscle. (299 aa)
prkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
egfrReceptor protein-tyrosine kinase. (1206 aa)
LOC102206349Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (515 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (653 aa)
ENSPNYP00000025478Tubulin domain-containing protein. (151 aa)
ENSPNYP00000025611Tubulin domain-containing protein. (106 aa)
ENSPNYP00000025623Tubulin domain-containing protein. (67 aa)
ENSPNYP00000025641Si:ch73-199e17.1; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (584 aa)
LOC102210300Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (385 aa)
LOC1022115445-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1. (517 aa)
htr2a5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (463 aa)
LOC102200516Uncharacterized protein. (361 aa)
ENSPNYP00000027112Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (441 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1083 aa)
LOC102193199Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (311 aa)
LOC102213574Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (432 aa)
map2k5Mitogen-activated protein kinase kinase 5. (409 aa)
LOC102202877Glutamate receptor, metabotropic 1b. (1175 aa)
LOC102200234Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1097 aa)
LOC102198516Zgc:55558. (186 aa)
gucy1b1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (594 aa)
ENSPNYP00000011447Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (291 aa)
ENSPNYP00000011458Uncharacterized protein. (101 aa)
LOC102210075Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (246 aa)
LOC102208768Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (198 aa)
CSNK1DCasein kinase 1 delta. (383 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1275 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
lpar1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSPNYP00000012665Tubulin domain-containing protein. (82 aa)
LOC102192308Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (971 aa)
LOC102194398Receptor protein-tyrosine kinase. (1038 aa)
adcy7Adenylate cyclase 7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (955 aa)
LOC102207311Glutamate receptor, metabotropic 1a. (1165 aa)
adcy2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1070 aa)
LOC102209105Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (588 aa)
pdgfraPlatelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1460 aa)
GNASGNAS complex locus. (379 aa)
LOC102200506Uncharacterized protein. (239 aa)
LOC102201843GRB2 related adaptor protein 2a. (290 aa)
adcy5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
LOC102213139Uncharacterized protein. (359 aa)
LOC102201029Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (434 aa)
LOC102212804Dopamine receptor D2 like; Belongs to the G-protein coupled receptor 1 family. (489 aa)
LOC102213840Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (429 aa)
ENSPNYP00000017487GNAS complex locus. (376 aa)
LOC102192069Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
LOC102202611Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
LOC102205468Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1154 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2672 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (861 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (351 aa)
ENSPNYP00000019127Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
LOC102192349Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
grm5Glutamate receptor, metabotropic 5b. (1219 aa)
LOC102197140Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1083 aa)
pdgfdPlatelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family. (371 aa)
LOC102211734Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (801 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (292 aa)
LOC102197068GRB2 related adaptor protein 2b. (227 aa)
ENSPNYP00000020486Dopamine receptor D1b; Belongs to the G-protein coupled receptor 1 family. (465 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa)
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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