(83 nodes) Regulation of exocytosis network (Opisthocomus hoazin)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	N306_10522	Synaptotagmin-1. (424 aa)
	N306_07252	Synaptotagmin-17. (464 aa)
	N306_07942	Rabphilin-3A. (617 aa)
	N306_15279	Ras-related protein Rab-27A. (221 aa)
	N306_12951	Synaptotagmin-10. (472 aa)
	N306_02214	Synaptotagmin-12. (340 aa)
	N306_06834	Tyrosine-protein kinase. (443 aa)
	N306_13007	Synaptotagmin-4. (414 aa)
	N306_12786	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	N306_10205	Synaptotagmin-2. (404 aa)
	N306_08520	Hepatocyte growth factor-regulated tyrosine kinase substrate. (631 aa)
	N306_07331	Interleukin-1 receptor accessory protein-like 1. (437 aa)
	N306_08727	Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (327 aa)
	N306_10729	Ras-related protein Rab-10. (159 aa)
	N306_15547	Ras-related protein Rab-3C. (221 aa)
	N306_00568	Ras-related protein Rab-8A. (125 aa)
	N306_00957	Lysosome-associated membrane glycoprotein 1. (406 aa)
	N306_00653	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1475 aa)
	N306_02042	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (547 aa)
	N306_01130	Glutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (879 aa)
	N306_10812	Syntaxin-binding protein 5. (921 aa)
	N306_09171	Peripheral plasma membrane protein CASK. (312 aa)
	N306_01220	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
	N306_08062	Vacuolar protein sorting-associated protein 18. (951 aa)
	N306_09340	CLIP-associating protein 2. (1372 aa)
	N306_09565	Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (577 aa)
	N306_07360	Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2158 aa)
	N306_15162	Synaptotagmin-13. (429 aa)
	N306_03776	Zona pellucida sperm-binding protein 3. (288 aa)
	N306_09418	Two pore calcium channel protein 2. (715 aa)
	N306_07427	Tyrosine-protein kinase. (611 aa)
	N306_10457	Rab5 GDP/GTP exchange factor. (491 aa)
	N306_02556	Sodium-driven chloride bicarbonate exchanger. (164 aa)
	N306_15247	Ras-related protein Rab-8B. (169 aa)
	N306_03048	PDZ domain-containing protein GIPC1. (240 aa)
	N306_09310	Sorting nexin-4. (402 aa)
	N306_12094	Double C2-like domain-containing protein beta. (649 aa)
	N306_08207	Ras-related protein Rab-27B. (218 aa)
	N306_04300	Anion exchange protein. (1036 aa)
	N306_06890	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (389 aa)
	N306_08521	Septin-5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (294 aa)
	N306_12469	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (457 aa)
	N306_13727	CLIP-associating protein 1. (1480 aa)
	N306_08522	Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (351 aa)
	N306_10650	Syntaxin-binding protein 5-like. (1091 aa)
	N306_12061	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (340 aa)
	N306_04864	Ras-related protein Rab-12. (179 aa)
	N306_04372	Ras-related protein Rap-1b. (184 aa)
	N306_09341	Programmed cell death 6-interacting protein. (798 aa)
	N306_04051	Rap guanine nucleotide exchange factor 4. (991 aa)
	N306_13484	Leucine-rich repeat serine/threonine-protein kinase 2. (2451 aa)
	N306_01634	Regulating synaptic membrane exocytosis protein 4. (237 aa)
	N306_12483	Vacuolar-sorting protein SNF8. (226 aa)
	N306_15068	Fragile X mental retardation protein 1 B. (549 aa)
	N306_15086	X-linked interleukin-1 receptor accessory protein-like 2. (660 aa)
	N306_06983	Calcium-dependent secretion activator 2. (1188 aa)
	N306_01201	Synaptotagmin-11. (418 aa)
	N306_00854	Ras-related protein Rab-10. (88 aa)
	N306_03779	Zona pellucida sperm-binding protein 3. (275 aa)
	N306_09663	Tumor susceptibility 101. (378 aa)
	N306_03780	Zona pellucida sperm-binding protein 3. (287 aa)
	N306_06553	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (176 aa)
	N306_04133	Vacuolar protein sorting-associated protein 4B. (150 aa)
	N306_02793	Fibrinogen gamma chain. (105 aa)
	N306_04134	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (180 aa)
	N306_03477	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (882 aa)
	N306_08595	Synaptotagmin-9. (442 aa)
	N306_02833	RE1-silencing transcription factor. (862 aa)
	N306_08795	Voltage-dependent L-type calcium channel subunit beta-4. (424 aa)
	N306_12412	Tyrosine-protein kinase. (513 aa)
	N306_12590	Signal transducing adapter molecule 1. (531 aa)
	N306_11141	E3 ubiquitin-protein ligase parkin. (287 aa)
	N306_00930	85/88 kDa calcium-independent phospholipase A2. (806 aa)
	N306_09164	Protein kinase domain-containing protein. (52 aa)
	N306_14443	Uncharacterized protein C12orf4. (550 aa)
	N306_02624	Amyloid beta A4 protein-binding family A member 1. (823 aa)
	N306_02972	ARF GTPase-activating protein GIT2. (716 aa)
	N306_14191	Rab3 GTPase-activating protein catalytic subunit. (965 aa)
	N306_02991	Adenylate cyclase type 1. (1090 aa)
	N306_07542	Ras-related protein Rab-3B. (219 aa)
	N306_02603	Annexin. (320 aa)
	N306_01787	PML-RARA-regulated adapter molecule 1. (68 aa)
	N306_10702	Synaptotagmin-6. (441 aa)

Your Current Organism:

Opisthocomus hoazin

NCBI taxonomy Id: 30419
Other names: O. hoazin, Opisthocomus hoazin hoazin, hoatzin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N306_00568	N306_07542	A0A091V592	A0A091WGZ2	Ras-related protein Rab-8A.	Ras-related protein Rab-3B.	0.471
N306_00568	N306_09340	A0A091V592	A0A091X9D6	Ras-related protein Rab-8A.	CLIP-associating protein 2.	0.401
N306_00568	N306_13727	A0A091V592	A0A091VCM5	Ras-related protein Rab-8A.	CLIP-associating protein 1.	0.461
N306_00568	N306_15247	A0A091V592	A0A091XXK5	Ras-related protein Rab-8A.	Ras-related protein Rab-8B.	0.823
N306_00568	N306_15547	A0A091V592	A0A091WQP8	Ras-related protein Rab-8A.	Ras-related protein Rab-3C.	0.471
N306_00653	N306_01201	A0A091WRG1	A0A091W7A4	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Synaptotagmin-11.	0.537
N306_00653	N306_04051	A0A091WRG1	A0A091W3P6	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Rap guanine nucleotide exchange factor 4.	0.553
N306_00653	N306_10205	A0A091WRG1	A0A091WNU9	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Synaptotagmin-2.	0.514
N306_00653	N306_10522	A0A091WRG1	A0A091WHN1	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Synaptotagmin-1.	0.514
N306_00653	N306_11141	A0A091WRG1	A0A091WD51	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	E3 ubiquitin-protein ligase parkin.	0.604
N306_00653	N306_13007	A0A091WRG1	A0A091WMC9	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Synaptotagmin-4.	0.537
N306_00854	N306_07542	A0A091W6J6	A0A091WGZ2	Ras-related protein Rab-10.	Ras-related protein Rab-3B.	0.466
N306_00854	N306_09340	A0A091W6J6	A0A091X9D6	Ras-related protein Rab-10.	CLIP-associating protein 2.	0.401
N306_00854	N306_13727	A0A091W6J6	A0A091VCM5	Ras-related protein Rab-10.	CLIP-associating protein 1.	0.401
N306_00854	N306_15547	A0A091W6J6	A0A091WQP8	Ras-related protein Rab-10.	Ras-related protein Rab-3C.	0.466
N306_00957	N306_08207	A0A091V4P0	A0A091VND1	Lysosome-associated membrane glycoprotein 1.	Ras-related protein Rab-27B.	0.518
N306_00957	N306_08520	A0A091V4P0	A0A091WNX3	Lysosome-associated membrane glycoprotein 1.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.437
N306_00957	N306_09663	A0A091V4P0	A0A091W8U4	Lysosome-associated membrane glycoprotein 1.	Tumor susceptibility 101.	0.508
N306_00957	N306_15279	A0A091V4P0	A0A091WJU2	Lysosome-associated membrane glycoprotein 1.	Ras-related protein Rab-27A.	0.518
N306_01130	N306_09171	A0A091WYP1	A0A091X4P4	Glutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Peripheral plasma membrane protein CASK.	0.994