(25 nodes) Butanoate metabolism network (Opisthocomus hoazin)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N306_04064	Glutamate decarboxylase 1. (491 aa)
	N306_12306	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (126 aa)
	N306_12514	Uncharacterized protein. (345 aa)
	N306_05100	Glutamate decarboxylase 2. (491 aa)
	N306_07196	Uncharacterized protein. (558 aa)
	N306_13573	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
	N306_13571	Uncharacterized protein. (153 aa)
	N306_06518	Acetoacetyl-CoA synthetase. (633 aa)
	N306_00992	Uncharacterized protein. (271 aa)
	N306_01831	DAO domain-containing protein. (379 aa)
	N306_15488	Uncharacterized protein. (480 aa)
	N306_11356	Aldedh domain-containing protein. (382 aa)
	N306_06624	Uncharacterized protein. (218 aa)
	N306_06255	Pyruvate carboxyltransferase domain-containing protein. (277 aa)
	N306_15496	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (525 aa)
	N306_13572	Uncharacterized protein. (133 aa)
	N306_08762	3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic. (286 aa)
	N306_03326	Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (164 aa)
	N306_14505	Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. (334 aa)
	N306_07264	Uncharacterized protein. (566 aa)
	N306_07267	Uncharacterized protein. (543 aa)
	N306_01418	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (325 aa)
	N306_07263	Uncharacterized protein. (581 aa)
	N306_00433	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
	N306_02891	3-hydroxybutyrate dehydrogenase type 2. (221 aa)

Your Current Organism:

Opisthocomus hoazin

NCBI taxonomy Id: 30419
Other names: O. hoazin, Opisthocomus hoazin hoazin, hoatzin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N306_00433	N306_00992	A0A091WDW7	A0A091VYP5	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.977
N306_00433	N306_01418	A0A091WDW7	A0A091WG06	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.978
N306_00433	N306_02891	A0A091WDW7	A0A091WCZ3	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyrate dehydrogenase type 2.	0.601
N306_00433	N306_03326	A0A091WDW7	A0A091WL30	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Peroxisomal bifunctional enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.	0.952
N306_00433	N306_06255	A0A091WDW7	A0A091WWK2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Pyruvate carboxyltransferase domain-containing protein.	0.890
N306_00433	N306_06518	A0A091WDW7	A0A091VY27	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acetoacetyl-CoA synthetase.	0.897
N306_00433	N306_07196	A0A091WDW7	A0A091W9S7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.574
N306_00433	N306_07263	A0A091WDW7	A0A091WFI1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.661
N306_00433	N306_07264	A0A091WDW7	A0A091WHZ6	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.661
N306_00433	N306_07267	A0A091WDW7	A0A091WH35	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.661
N306_00433	N306_08762	A0A091WDW7	A0A091WNV0	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic.	0.890
N306_00433	N306_11356	A0A091WDW7	A0A091XSR6	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Aldedh domain-containing protein.	0.597
N306_00433	N306_12306	A0A091WDW7	A0A091W8U7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.889
N306_00433	N306_12514	A0A091WDW7	A0A091WAD3	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.895
N306_00433	N306_14505	A0A091WDW7	A0A091WJH6	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family.	0.865
N306_00433	N306_15488	A0A091WDW7	A0A091XYP4	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.908
N306_00433	N306_15496	A0A091WDW7	A0A091WQM2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.978
N306_00992	N306_00433	A0A091VYP5	A0A091WDW7	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.977
N306_00992	N306_01418	A0A091VYP5	A0A091WG06	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.842
N306_00992	N306_02891	A0A091VYP5	A0A091WCZ3	Uncharacterized protein.	3-hydroxybutyrate dehydrogenase type 2.	0.644