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| | ftsY | Putative signal recognition particle receptor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (347 aa) |
| | rplX | 50S ribosomal protein LX. (58 aa) |
| | aif6 | Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (220 aa) |
| | rpl31e | 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family. (85 aa) |
| | rpl39e | 50S ribosomal protein L39e; Belongs to the eukaryotic ribosomal protein eL39 family. (50 aa) |
| | MCP_0014 | Conserved hypothetical protein. (195 aa) |
| | MCP_0015 | DNA-binding protein; Belongs to the PDCD5 family. (111 aa) |
| | rps19e | 30S ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (151 aa) |
| | MCP_0045 | GTP-binding protein. (338 aa) |
| | tbp-1 | TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (188 aa) |
| | MCP_0187 | Peptidyl-prolyl cis-trans isomerase. (145 aa) |
| | ef1b | Elongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa) |
| | MCP_0197 | Conserved hypothetical protein; Contains two Protein of unknown function DUF1610 domains (IPR011668). (55 aa) |
| | MCP_0206 | Conserved hypothetical protein; Belongs to the NMD3 family (IPR007064). (358 aa) |
| | MCP_0213 | RNase L inhibitor. (589 aa) |
| | rps17e | 30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (65 aa) |
| | MCP_0251 | Truncated threonyl-tRNA synthetase. (477 aa) |
| | eif2g | Translation initiation factor 2 gamma subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (410 aa) |
| | rpoE1 | DNA-directed RNA polymerase subunit E'. (195 aa) |
| | rpl10e | 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. (172 aa) |
| | eif2b | Translation initiation factor 2 beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (205 aa) |
| | MCP_0397 | Conserved hypothetical protein; Contains one Helix-turn-helix type 3 domain (IPR001387). (134 aa) |
| | MCP_0407 | Truncated threonyl-tRNA synthetase. (169 aa) |
| | aif1a-1 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (79 aa) |
| | rpl21e | 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (102 aa) |
| | MCP_0724 | Putative DNA-directed RNA polymerase subunit F. (116 aa) |
| | ksgA | Probable dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (276 aa) |
| | rpl40e | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (48 aa) |
| | MCP_0829 | Conserved hypothetical protein. (165 aa) |
| | MCP_0832 | DNA repair helicase. (726 aa) |
| | rps3Ae | 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (227 aa) |
| | dphB | Probable diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. (274 aa) |
| | map-1 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (296 aa) |
| | MCP_1003 | Putative HTH-type transcriptional regulator; Belongs to the Conserved hypothetical protein 270 family (IPR004451). (167 aa) |
| | infB | Probable translation initiation factor 2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (593 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (152 aa) |
| | rpl24e | 50S ribosomal protein L24e; Binds to the 23S rRNA. (71 aa) |
| | rps28e | 30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (70 aa) |
| | rpl7ae | 50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (123 aa) |
| | MCP_1049 | NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (320 aa) |
| | MCP_1050 | Conserved hypothetical protein; Belongs to the Protein of unknown function UPF0113 family (IPR005155). (175 aa) |
| | truD | Probable tRNA pseudouridine synthase D; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (434 aa) |
| | rpoH | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (79 aa) |
| | rpoB2 | DNA-directed RNA polymerase subunit B''; Belongs to the RNA polymerase beta chain family. (514 aa) |
| | rpoB1 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa) |
| | rpoA1 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (877 aa) |
| | rpoA2 | DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (389 aa) |
| | rpl30e | 50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (104 aa) |
| | nusA | NusA protein homolog; Participates in transcription termination. Belongs to the NusA family. (147 aa) |
| | rps12p | 30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa) |
| | rps7p | 30S ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (188 aa) |
| | fusA | Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (732 aa) |
| | tuf | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (426 aa) |
| | rps10p | 30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (104 aa) |
| | MCP_1285 | Putative TATA-box-binding protein. (97 aa) |
| | MCP_1353 | Hypothetical protein; Belongs to the Phosphoesterase, PA-phosphatase related family (IPR000326). (304 aa) |
| | MCP_1404 | Putative diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (323 aa) |
| | MCP_1415 | Putative small nucleolar RNP Sm protein. (74 aa) |
| | MCP_1465 | Putative serine/threonine kinase. (289 aa) |
| | rpoL | DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (95 aa) |
| | tfe | Transcription initiation factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comple [...] (170 aa) |
| | MCP_1531 | Putative serine/threonine kinase. (256 aa) |
| | MCP_1532 | Conserved hypothetical protein; Contains one KH domain (IPR004087); Contains one KH, type 1 domain (IPR004088). (180 aa) |
| | eif2a | Translation initiation factor 2 alpha subunit. (267 aa) |
| | rps27e | 30S ribosomal protein S27e. (61 aa) |
| | rpl44e | 50S ribosomal protein L44E; Binds to the 23S rRNA. (93 aa) |
| | MCP_1556 | snoRNA binding protein Nop56 homolog. (248 aa) |
| | flpA | rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (222 aa) |
| | MCP_1584 | Conserved hypothetical protein. (145 aa) |
| | rps2p | 30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (211 aa) |
| | rpoK | DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (73 aa) |
| | rpoN | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (71 aa) |
| | rps9p | 30S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (134 aa) |
| | rpl13p | 50S ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (139 aa) |
| | rpl18e | 50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | rps6e | 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (146 aa) |
| | aif5A | Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (128 aa) |
| | rps15p | 30S ribosomal protein S15P/S13e. (152 aa) |
| | MCP_1760 | DNA repair helicase. (453 aa) |
| | rps8e | 30S ribosomal protein S8e. (126 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (474 aa) |
| | tbp-2 | TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (188 aa) |
| | rrmJ | Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (254 aa) |
| | MCP_1891 | GTP-binding protein. (524 aa) |
| | MCP_2009 | Conserved hypothetical protein; Contains one Heat shock protein DnaJ, N-terminal domain (IPR001623). (185 aa) |
| | MCP_2059 | Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (471 aa) |
| | MCP_2065 | Belongs to the Uncharacterised conserved protein UCP015877, zinc finger family (IPR012041). (220 aa) |
| | rpl12p | 50S ribosomal protein L12P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (103 aa) |
| | rplP0 | Acidic ribosomal protein P0 homolog; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (303 aa) |
| | rpl1p | 50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa) |
| | rpl11p | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (160 aa) |
| | MCP_2093 | Hypothetical protein. (246 aa) |
| | aif1a-2 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (92 aa) |
| | MCP_2117 | Hypothetical protein. (135 aa) |
| | spt5 | Putative ribosomal protein L26e; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (162 aa) |
| | secE | Protein transport protein SEC61 gamma subunit homolog; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (69 aa) |
| | MCP_2142 | Ribose-1,5-bisphosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family. (322 aa) |
| | MCP_2153 | Belongs to the Conserved hypothetical protein 289 family (IPR005237). (220 aa) |
| | aif1a-3 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (112 aa) |
| | rpl3p | 50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (341 aa) |
| | rpl4p | 50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (250 aa) |
| | rpl23p | 50S ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (85 aa) |
| | rpl2p | 50S ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (240 aa) |
| | rps19p | 30S ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa) |
| | rpl22p | 50S ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (155 aa) |
| | rps3p | 30S ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (292 aa) |
| | rpl29p | 50S ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (66 aa) |
| | MCP_2228 | Protein translation factor SUI1 homolog; Belongs to the SUI1 family. (101 aa) |
| | rps17p | 30S ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (110 aa) |
| | rpl14p | 50S ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rpl24p | 50S ribosomal protein L24P; Located at the polypeptide exit tunnel on the outside of the subunit. (124 aa) |
| | rps4e | 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (234 aa) |
| | rpl5p | 50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (170 aa) |
| | rps14p | 30S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (50 aa) |
| | rps8p | 30S ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpl6p | 50S ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rpl32e | 50S ribosomal protein L32e. (219 aa) |
| | rpl19e | 50S ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (147 aa) |
| | rpl18p | 50S ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (188 aa) |
| | rps5p | 30S ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (207 aa) |
| | rpl30p | 50S ribosomal protein L30P. (153 aa) |
| | rpl15p | 50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (149 aa) |
| | secY | Protein transport protein SEC61 subunit alpha homolog; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (506 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | cmk | Cytidylate kinase. (177 aa) |
| | rps13p | 30S ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (225 aa) |
| | rps4p | 30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa) |
| | rps11p | 30S ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rpoD | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (262 aa) |
| | rpl37e | 50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (59 aa) |
| | MCP_2284 | Putative small nucleolar RNP Sm protein; Belongs to the snRNP Sm proteins family. (72 aa) |
| | tfs | Archaeal transcription factor S. (94 aa) |
| | MCP_2339 | Protein translation factor SUI1 homolog; Belongs to the SUI1 family. (102 aa) |
| | map-2 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (289 aa) |
| | aif1a-4 | Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (90 aa) |
| | rtcA | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (340 aa) |
| | tfb | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (336 aa) |
| | srp19 | Signal recognition particle 19 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. (97 aa) |
| | rpoP | DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. (45 aa) |
| | rpl37ae | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. (94 aa) |
| | MCP_2629 | Conserved hypothetical protein; Belongs to the Shwachman-Bodian-Diamond syndrome proteins family (IPR002140). (231 aa) |
| | rpl15e | 50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa) |
| | srp54 | Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (442 aa) |
| | rps27ae | 30S ribosomal protein S27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (76 aa) |
| | rps24e | 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa) |
| | MCP_2673 | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (180 aa) |
| | rpoE2 | DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (74 aa) |
| | prf1 | Peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (415 aa) |
| | MCP_2732 | Conserved hypothetical protein; Belongs to the YbhB and YbcL family (IPR005247); Contains one PEBP domain (IPR008914). (160 aa) |
| | engB | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation. (212 aa) |
| | polC | Family D DNA polymerase large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1129 aa) |
| | MCP_2962 | Conserved hypothetical protein; Contains one Translation elongation factor EFTu/EF1A, domain 2 (IPR004161). (341 aa) |
| | nac | Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family. (117 aa) |
