STRINGSTRING
RFC3 RFC3 POLA2 POLA2 POLE POLE LIG1 LIG1 RFC4 RFC4 PCNA PCNA POLE2 POLE2 ATAD5 ATAD5 RFC2 RFC2 PRIM2 PRIM2 RFC5 RFC5 POLE4 POLE4 RAD17 RAD17 RFC1 RFC1 POLE3 POLE3 PRIM1 PRIM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC3Replication factor C subunit 3. (356 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa)
LIG1DNA ligase. (1303 aa)
RFC4Replication factor C subunit 4. (364 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
ATAD5ATPase family AAA domain containing 5. (1893 aa)
RFC2Replication factor C subunit 2. (352 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (510 aa)
RFC5Replication factor C subunit 5. (527 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (120 aa)
RAD17RAD17 checkpoint clamp loader component. (708 aa)
RFC1Replication factor C subunit 1. (1146 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (418 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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