STRINGSTRING
GATA2 GATA2 GATA6 GATA6 TBX21 TBX21 MYOG MYOG MYOCD MYOCD ASCL5 ASCL5 MEF2A MEF2A MESP1 MESP1 CBFB CBFB TBX5 TBX5 LMO1 LMO1 NFATC2 NFATC2 ZFPM2 ZFPM2 TCF12 TCF12 ID2 ID2 GATA4 GATA4 MYF6 MYF6 LDB2 LDB2 RUNX3 RUNX3 LMO3 LMO3 TCF3 TCF3 TAL1 TAL1 ETS2 ETS2 NFATC4 NFATC4 LYL1 LYL1 TCF4 TCF4 LMCD1 LMCD1 ID4 ID4 PPM1D PPM1D LDB1 LDB1 GATA5 GATA5 LMO2 LMO2 PAX3 PAX3 A0A4W2ENQ5 A0A4W2ENQ5 MYF5 MYF5 MEF2B MEF2B RUNX1 RUNX1 ID3 ID3 NHLH1 NHLH1 NKX2-5 NKX2-5 NFATC3 NFATC3 ID1 ID1 ETS1 ETS1 MEF2D MEF2D PAX7 PAX7 HAND2 HAND2 MEF2C MEF2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GATA2GATA binding protein 2. (596 aa)
GATA6GATA binding protein 6. (662 aa)
TBX21T-box transcription factor 21. (532 aa)
MYOGMyogenin. (224 aa)
MYOCDMyocardin. (981 aa)
ASCL5Achaete-scute family bHLH transcription factor 5. (189 aa)
MEF2AMyocyte enhancer factor 2A. (503 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (256 aa)
CBFBCore-binding factor subunit beta. (187 aa)
TBX5T-box transcription factor 5. (561 aa)
LMO1LIM domain only 1. (172 aa)
NFATC2Nuclear factor of activated T cells 2. (914 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
TCF12Transcription factor 12. (706 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
GATA4GATA binding protein 4. (660 aa)
MYF6Myogenic factor 6. (422 aa)
LDB2LIM domain binding 2. (373 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (434 aa)
LMO3LIM domain only 3. (156 aa)
TCF3Transcription factor 3. (640 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (328 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (471 aa)
NFATC4Nuclear factor of activated T cells 4. (979 aa)
LYL1LYL1 basic helix-loop-helix family member. (305 aa)
TCF4Transcription factor 4. (775 aa)
LMCD1LIM and cysteine rich domains 1. (363 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (164 aa)
PPM1DProtein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa)
LDB1LIM domain binding 1. (411 aa)
GATA5GATA binding protein 5. (403 aa)
LMO2LIM domain only 2. (340 aa)
PAX3Paired box 3. (484 aa)
A0A4W2ENQ5LIM zinc-binding domain-containing protein. (85 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
MEF2BMyocyte enhancer factor 2B. (368 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
NKX2-5NK2 homeobox 5. (323 aa)
NFATC3Nuclear factor of activated T cells 3. (1073 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
MEF2DMyocyte enhancer factor 2D. (514 aa)
PAX7Paired box 7. (505 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.