(25 nodes) Calcitonin-like ligand receptors, and Corticotropin-releasing factor network (Bos indicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

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Others

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protein homology

Your Input:
	ADM2	Adrenomedullin 2. (142 aa)
	RAMP2	Receptor activity modifying protein 2. (182 aa)
	CRHR2	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa)
	CRH	Corticotropin releasing hormone. (190 aa)
	PTH2	Parathyroid hormone 2. (129 aa)
	PTH2R	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (561 aa)
	PTH	Parathyroid hormone. (147 aa)
	CRHR1	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (435 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (324 aa)
	RAMP1	Receptor activity modifying protein 1. (148 aa)
	FBXO34	F-box protein 34. (766 aa)
	A0A4W2E8R7	CALCITONIN domain-containing protein. (168 aa)
	PTH1R	Parathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (589 aa)
	RAMP3	Receptor activity modifying protein 3. (150 aa)
	UCN3	Urocortin 3. (166 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (548 aa)
	A0A4W2EYA7	Uncharacterized protein. (79 aa)
	PTHLH	Parathyroid hormone like hormone. (177 aa)
	CALCRL	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
	UCN2	Urocortin 2. (112 aa)
	LOC113905107	CALCITONIN domain-containing protein. (143 aa)
	LOC113905106	CALCITONIN domain-containing protein. (123 aa)
	LOC113905044	Uncharacterized protein. (125 aa)
	ADM	Uncharacterized protein. (456 aa)
	UCN	Urocortin. (129 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2E8R7	A0A4W2EYA7	A0A4W2E8R7	A0A4W2EYA7	CALCITONIN domain-containing protein.	Uncharacterized protein.	0.847
A0A4W2E8R7	ADM	A0A4W2E8R7	A0A4W2HV24	CALCITONIN domain-containing protein.	Uncharacterized protein.	0.855
A0A4W2E8R7	ADM2	A0A4W2E8R7	A0A4W2CEA9	CALCITONIN domain-containing protein.	Adrenomedullin 2.	0.428
A0A4W2E8R7	CALCR	A0A4W2E8R7	A0A4W2EW56	CALCITONIN domain-containing protein.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.968
A0A4W2E8R7	CALCRL	A0A4W2E8R7	A0A4W2F5G3	CALCITONIN domain-containing protein.	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family.	0.983
A0A4W2E8R7	LOC113905044	A0A4W2E8R7	A0A4W2HSX5	CALCITONIN domain-containing protein.	Uncharacterized protein.	0.926
A0A4W2E8R7	LOC113905106	A0A4W2E8R7	A0A4W2HSU2	CALCITONIN domain-containing protein.	CALCITONIN domain-containing protein.	0.925
A0A4W2E8R7	RAMP1	A0A4W2E8R7	A0A4W2DD69	CALCITONIN domain-containing protein.	Receptor activity modifying protein 1.	0.963
A0A4W2E8R7	RAMP2	A0A4W2E8R7	A0A4W2CH42	CALCITONIN domain-containing protein.	Receptor activity modifying protein 2.	0.937
A0A4W2E8R7	RAMP3	A0A4W2E8R7	A0A4W2EA07	CALCITONIN domain-containing protein.	Receptor activity modifying protein 3.	0.915
A0A4W2EYA7	A0A4W2E8R7	A0A4W2EYA7	A0A4W2E8R7	Uncharacterized protein.	CALCITONIN domain-containing protein.	0.847
A0A4W2EYA7	ADM	A0A4W2EYA7	A0A4W2HV24	Uncharacterized protein.	Uncharacterized protein.	0.909
A0A4W2EYA7	ADM2	A0A4W2EYA7	A0A4W2CEA9	Uncharacterized protein.	Adrenomedullin 2.	0.416
A0A4W2EYA7	CALCR	A0A4W2EYA7	A0A4W2EW56	Uncharacterized protein.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.980
A0A4W2EYA7	CALCRL	A0A4W2EYA7	A0A4W2F5G3	Uncharacterized protein.	Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family.	0.950
A0A4W2EYA7	CRHR2	A0A4W2EYA7	A0A4W2CM17	Uncharacterized protein.	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.465
A0A4W2EYA7	LOC113905044	A0A4W2EYA7	A0A4W2HSX5	Uncharacterized protein.	Uncharacterized protein.	0.817
A0A4W2EYA7	LOC113905106	A0A4W2EYA7	A0A4W2HSU2	Uncharacterized protein.	CALCITONIN domain-containing protein.	0.877
A0A4W2EYA7	LOC113905107	A0A4W2EYA7	A0A4W2HSR3	Uncharacterized protein.	CALCITONIN domain-containing protein.	0.888
A0A4W2EYA7	RAMP1	A0A4W2EYA7	A0A4W2DD69	Uncharacterized protein.	Receptor activity modifying protein 1.	0.940

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