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PDE12 PDE12 EIF4H EIF4H NUFIP2 NUFIP2 CNOT10 CNOT10 PAN3 PAN3 DCP2 DCP2 LSM12 LSM12 PAIP1 PAIP1 KIF1BP KIF1BP CNOT7 CNOT7 NOCT NOCT LSM14A LSM14A EIF4G2 EIF4G2 BTG2 BTG2 PATL1 PATL1 CNOT3 CNOT3 TNKS1BP1 TNKS1BP1 PABPC1 PABPC1 USP10 USP10 EIF4A1 EIF4A1 NAXD NAXD PAN2 PAN2 A0A4W2CVR4 A0A4W2CVR4 CNOT11 CNOT11 TIA1 TIA1 NUDT4 NUDT4 EIF4B EIF4B CAPRIN1 CAPRIN1 EIF4A2 EIF4A2 CNOT6 CNOT6 EIF4G1 EIF4G1 XRN1 XRN1 EIF4EBP3 EIF4EBP3 CNOT2 CNOT2 EIF4G3 EIF4G3 EIF4E EIF4E BTG3 BTG3 DDX3X DDX3X G3BP1 G3BP1 A0A4W2DQ16 A0A4W2DQ16 DCP1A DCP1A EIF4E1B EIF4E1B A0A4W2DRH2 A0A4W2DRH2 G3BP2 G3BP2 TOB1 TOB1 EDC4 EDC4 HELZ HELZ DCP1B DCP1B PABPC1L PABPC1L CNOT9 CNOT9 FAM98A FAM98A EIF4EBP1 EIF4EBP1 A0A4W2ECM3 A0A4W2ECM3 RC3H1 RC3H1 EIF4ENIF1 EIF4ENIF1 LSM14B LSM14B CNOT4 CNOT4 CCDC142 CCDC142 PATL2 PATL2 SLC38A6 SLC38A6 NAXE NAXE A0A4W2F0N3 A0A4W2F0N3 CNOT8 CNOT8 TOB2 TOB2 EDC3 EDC3 TRNAU1AP TRNAU1AP A0A4W2FX29 A0A4W2FX29 CNOT1 CNOT1 CNOT6L CNOT6L DDX6 DDX6 A0A4W2HME0 A0A4W2HME0 EIF4E2 EIF4E2 EIF4EBP2 EIF4EBP2 RC3H2 RC3H2 PABPC4 PABPC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE12Phosphodiesterase 12. (609 aa)
EIF4HEukaryotic translation initiation factor 4H. (228 aa)
NUFIP2Nuclear FMR1 interacting protein 2. (697 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (803 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (1017 aa)
DCP2Decapping mRNA 2. (423 aa)
LSM12LSM12 homolog. (195 aa)
PAIP1Poly(A) binding protein interacting protein 1. (483 aa)
KIF1BPKIF1 binding protein. (621 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
NOCTNocturnin. (530 aa)
LSM14ALSM14A mRNA processing body assembly factor. (463 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (906 aa)
BTG2BTG anti-proliferation factor 2. (150 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (806 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (744 aa)
TNKS1BP1Tankyrase 1 binding protein 1. (1774 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (800 aa)
EIF4A1Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family. (406 aa)
NAXDATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (345 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1205 aa)
A0A4W2CVR4Q_MOTIF domain-containing protein. (93 aa)
CNOT11CCR4-NOT transcription complex subunit 11. (511 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
NUDT4Nudix hydrolase domain-containing protein. (181 aa)
EIF4BEukaryotic translation initiation factor 4B. (615 aa)
CAPRIN1Cell cycle associated protein 1. (708 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (407 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (568 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1601 aa)
XRN15'-3' exoribonuclease 1. (1727 aa)
EIF4EBP3Eukaryotic translation initiation factor 4E binding protein 3. (100 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (540 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1815 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
BTG3BTG anti-proliferation factor 3. (252 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (645 aa)
G3BP1G3BP stress granule assembly factor 1. (465 aa)
A0A4W2DQ16Uncharacterized protein; Belongs to the DEAD box helicase family. (693 aa)
DCP1ADecapping mRNA 1A. (579 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (132 aa)
A0A4W2DRH2Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (390 aa)
G3BP2G3BP stress granule assembly factor 2. (482 aa)
TOB1Transducer of ERBB2, 1. (358 aa)
EDC4Enhancer of mRNA decapping 4. (1357 aa)
HELZHelicase with zinc finger. (1937 aa)
DCP1BDecapping mRNA 1B. (557 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (613 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
FAM98AFamily with sequence similarity 98 member A. (517 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (178 aa)
A0A4W2ECM3LSM14 domain-containing protein. (223 aa)
RC3H1Ring finger and CCCH-type domains 1. (1132 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (985 aa)
LSM14BLSM family member 14B. (424 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (713 aa)
CCDC142Coiled-coil domain containing 142. (760 aa)
PATL2PAT1 homolog 2. (534 aa)
SLC38A6Solute carrier family 38 member 6. (456 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (363 aa)
A0A4W2F0N3Q_MOTIF domain-containing protein. (88 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
TOB2Transducer of ERBB2, 2. (345 aa)
EDC3Enhancer of mRNA decapping 3. (508 aa)
TRNAU1APtRNA selenocysteine 1 associated protein 1. (287 aa)
A0A4W2FX29Helicase C-terminal domain-containing protein. (177 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2389 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (555 aa)
DDX6DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa)
A0A4W2HME0Uncharacterized protein. (171 aa)
EIF4E2Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
RC3H2Ring finger and CCCH-type domains 2. (1132 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (661 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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