STRINGSTRING
XPO4 XPO4 NUP58 NUP58 A0A4W2BQQ8 A0A4W2BQQ8 XPO6 XPO6 PIAS2 PIAS2 NUP50 NUP50 ZNF451 ZNF451 RANGAP1 RANGAP1 A0A4W2C2C7 A0A4W2C2C7 SUMO2 SUMO2 NUP85 NUP85 ZMIZ1 ZMIZ1 NXF1 NXF1 SEC13 SEC13 RAN RAN RANBP2 RANBP2 SAE1 SAE1 RNF169 RNF169 TOP2B TOP2B IPO9 IPO9 NUP160 NUP160 NUP188 NUP188 A0A4W2CSL4 A0A4W2CSL4 GLE1 GLE1 NUP205 NUP205 RCC1 RCC1 A0A4W2CY87 A0A4W2CY87 ZNF644 ZNF644 RANBP6 RANBP6 SENP1 SENP1 PIAS1 PIAS1 PIAS4 PIAS4 A0A4W2D7B2 A0A4W2D7B2 A0A4W2D833 A0A4W2D833 NUP214 NUP214 ZMIZ2 ZMIZ2 A0A4W2D9I6 A0A4W2D9I6 IPO13 IPO13 NUP42 NUP42 RAE1 RAE1 NDC1 NDC1 A0A4W2DES2 A0A4W2DES2 NUP210L NUP210L TDP1 TDP1 NUP210 NUP210 A0A4W2DP28 A0A4W2DP28 UBE2I UBE2I A0A4W2DTT0 A0A4W2DTT0 KPNB1 KPNB1 SNUPN SNUPN TPR TPR XPO5 XPO5 NUP93 NUP93 NUP88 NUP88 NUP133 NUP133 KPNA2 KPNA2 CSE1L CSE1L A0A4W2EBF5 A0A4W2EBF5 UBA2 UBA2 NUP98 NUP98 A0A4W2EEQ4 A0A4W2EEQ4 TOP1MT TOP1MT LOC113904343 LOC113904343 A0A4W2EGW0 A0A4W2EGW0 IPO5 IPO5 A0A4W2EHW8 A0A4W2EHW8 PPIA PPIA NUP107 NUP107 A0A4W2EKM6 A0A4W2EKM6 RANBP1 RANBP1 KPNA1 KPNA1 LDB3 LDB3 AAAS AAAS ZNF148 ZNF148 A0A4W2EQE8 A0A4W2EQE8 IPO4 IPO4 SENP2 SENP2 XPO7 XPO7 NFXL1 NFXL1 A0A4W2EWE1 A0A4W2EWE1 A0A4W2EXY1 A0A4W2EXY1 LOC113888692 LOC113888692 NUP37 NUP37 SENP7 SENP7 TNPO2 TNPO2 NUP155 NUP155 XPOT XPOT KPNA5 KPNA5 NXT1 NXT1 TDP2 TDP2 TOP1 TOP1 KPNA4 KPNA4 IPO11 IPO11 A0A4W2G3U7 A0A4W2G3U7 IPO7 IPO7 A0A4W2G7S7 A0A4W2G7S7 LOC113888099 LOC113888099 RANBP17 RANBP17 KPNA3 KPNA3 NUP43 NUP43 NFATC2IP NFATC2IP A0A4W2GQU3 A0A4W2GQU3 AHCTF1 AHCTF1 NUP35 NUP35 A0A4W2HGR3 A0A4W2HGR3 POM121C POM121C XPO1 XPO1 NCOA5 NCOA5 SUMO3 SUMO3 PIAS3 PIAS3 SENP5 SENP5 SUMO1 SUMO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XPO4Exportin 4. (1152 aa)
NUP58Nucleoporin 58. (586 aa)
A0A4W2BQQ8NTF2 domain-containing protein. (554 aa)
XPO6Exportin 6. (1125 aa)
PIAS2Protein inhibitor of activated STAT 2. (621 aa)
NUP50Nucleoporin 50. (465 aa)
ZNF451Zinc finger protein 451. (1058 aa)
RANGAP1Ran GTPase activating protein 1. (585 aa)
A0A4W2C2C7Uncharacterized protein. (467 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1112 aa)
NXF1Nuclear RNA export factor 1. (620 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (325 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
RANBP2RAN binding protein 2. (3143 aa)
SAE1SUMO1 activating enzyme subunit 1. (373 aa)
RNF169Ring finger protein 169. (708 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1619 aa)
IPO9Importin 9. (1040 aa)
NUP160Nucleoporin 160. (1402 aa)
NUP188Nucleoporin 188. (2017 aa)
A0A4W2CSL4PKS_ER domain-containing protein. (388 aa)
GLE1GLE1 RNA export mediator. (698 aa)
NUP205Nucleoporin 205. (2024 aa)
RCC1Regulator of chromosome condensation 1. (458 aa)
A0A4W2CY87Uncharacterized protein. (97 aa)
ZNF644Zinc finger protein 644. (1368 aa)
RANBP6Uncharacterized protein. (68 aa)
SENP1SUMO specific peptidase 1. (749 aa)
PIAS1Protein inhibitor of activated STAT 1. (702 aa)
PIAS4Protein inhibitor of activated STAT 4. (573 aa)
A0A4W2D7B2Uncharacterized protein. (83 aa)
A0A4W2D833Ubiquitin-like domain-containing protein. (61 aa)
NUP214Nucleoporin 214. (2141 aa)
ZMIZ2Zinc finger MIZ-type containing 2. (934 aa)
A0A4W2D9I6UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
IPO13Importin 13. (963 aa)
NUP42Nucleoporin 42. (420 aa)
RAE1Ribonucleic acid export 1. (367 aa)
NDC1NDC1 transmembrane nucleoporin. (784 aa)
A0A4W2DES2Uncharacterized protein. (116 aa)
NUP210LNucleoporin 210 like. (1883 aa)
TDP1Tyrosyl-DNA phosphodiesterase 1. (690 aa)
NUP210Nucleoporin 210. (1889 aa)
A0A4W2DP28GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
A0A4W2DTT0NTF2 domain-containing protein. (539 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
SNUPNSnurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family. (362 aa)
TPRTranslocated promoter region, nuclear basket protein. (2444 aa)
XPO5Exportin 5. (1204 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
NUP88Nucleoporin 88. (741 aa)
NUP133Nucleoporin 133. (1156 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
CSE1LChromosome segregation 1 like. (973 aa)
A0A4W2EBF5GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (640 aa)
NUP98Nucleoporin 98. (1816 aa)
A0A4W2EEQ4Ubiquitin-like domain-containing protein. (72 aa)
TOP1MTDNA topoisomerase I mitochondrial. (560 aa)
LOC113904343Uncharacterized protein. (169 aa)
A0A4W2EGW0Ubiquitin-like domain-containing protein. (80 aa)
IPO5Importin 5. (1097 aa)
A0A4W2EHW8Uncharacterized protein. (64 aa)
PPIAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (960 aa)
A0A4W2EKM6Small ubiquitin-related modifier. (104 aa)
RANBP1RAN binding protein 1. (206 aa)
KPNA1Karyopherin subunit alpha 1. (954 aa)
LDB3LIM domain binding 3. (791 aa)
AAASAladin WD repeat nucleoporin. (547 aa)
ZNF148Zinc finger protein 148. (794 aa)
A0A4W2EQE8Rad60-SLD domain-containing protein. (83 aa)
IPO4Importin 4. (1081 aa)
SENP2SUMO specific peptidase 2. (663 aa)
XPO7Exportin 7. (1096 aa)
NFXL1Nuclear transcription factor, X-box binding like 1. (895 aa)
A0A4W2EWE1Uncharacterized protein. (693 aa)
A0A4W2EXY1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (167 aa)
LOC113888692Uncharacterized protein. (109 aa)
NUP37Nucleoporin 37. (326 aa)
SENP7SUMO specific peptidase 7. (1047 aa)
TNPO2Transportin 2. (1097 aa)
NUP155Nucleoporin 155. (1449 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (986 aa)
KPNA5Importin subunit alpha; Functions in nuclear protein import. (539 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (364 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (769 aa)
KPNA4Importin subunit alpha; Functions in nuclear protein import. (511 aa)
IPO11Importin 11. (975 aa)
A0A4W2G3U7Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (116 aa)
IPO7Importin 7. (1038 aa)
A0A4W2G7S7Uncharacterized protein. (90 aa)
LOC113888099NTF2 domain-containing protein. (531 aa)
RANBP17RAN binding protein 17. (1106 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (521 aa)
NUP43Nucleoporin 43. (380 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (424 aa)
A0A4W2GQU3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
AHCTF1AT-hook containing transcription factor 1. (2276 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (327 aa)
A0A4W2HGR3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (158 aa)
POM121CUncharacterized protein. (1216 aa)
XPO1Exportin 1. (1071 aa)
NCOA5Nuclear receptor coactivator 5. (584 aa)
SUMO3Ubiquitin-like domain-containing protein. (134 aa)
PIAS3Protein inhibitor of activated STAT 3. (722 aa)
SENP5SUMO specific peptidase 5. (754 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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