STRINGSTRING
CHMP5 CHMP5 A0A4W2DA03 A0A4W2DA03 CHMP4A CHMP4A RASA1 RASA1 CHMP2A CHMP2A CEP55 CEP55 WASHC5 WASHC5 DCTN3 DCTN3 CFL1 CFL1 SNX18 SNX18 CHMP1A CHMP1A ANXA11 ANXA11 STMN1 STMN1 SEPTIN14 SEPTIN14 BIN3 BIN3 CHMP2B CHMP2B SPIRE2 SPIRE2 RHOA RHOA SNX33 SNX33 JTB JTB TMEM250 TMEM250 MYH9 MYH9 SON SON KIF20A KIF20A A0A4W2EWR2 A0A4W2EWR2 SEPTIN11 SEPTIN11 CHMP7 CHMP7 ZFYVE26 ZFYVE26 MITD1 MITD1 USP8 USP8 ANLN ANLN RHOB RHOB CIT CIT STAMBP STAMBP SEPTIN5 SEPTIN5 PLEC PLEC NUSAP1 NUSAP1 SEPTIN7 SEPTIN7 VPS4A VPS4A AURKB AURKB BIRC5 BIRC5 CHMP6 CHMP6 RAB35 RAB35 KIF4A KIF4A ROCK1 ROCK1 LZTS2 LZTS2 INCENP INCENP CKAP2 CKAP2 VPS4B VPS4B A0A4W2DQW9 A0A4W2DQW9 SEPTIN12 SEPTIN12 ALKBH4 ALKBH4 A0A4W2DJN4 A0A4W2DJN4 ACTR3 ACTR3 SEPTIN2 SEPTIN2 ECT2 ECT2 SEPTIN1 SEPTIN1 PLK1 PLK1 PDCD6IP PDCD6IP SEPTIN4 SEPTIN4 SPIRE1 SPIRE1 CENPA CENPA KLHDC8B KLHDC8B EFHC2 EFHC2 EFHC1 EFHC1 ARL3 ARL3 A0A4W2C4H3 A0A4W2C4H3 MYH10 MYH10 TRIM36 TRIM36 SEPTIN9 SEPTIN9 APC APC SHCBP1L SHCBP1L CHMP4C CHMP4C SEPTIN3 SEPTIN3 A0A4W2CHR1 A0A4W2CHR1 SEPTIN10 SEPTIN10 SPTBN1 SPTBN1 CUL7 CUL7 KLHDC8A KLHDC8A CNTROB CNTROB SPAST SPAST IST1 IST1 ROCK2 ROCK2 SNX9 SNX9 A0A4W2D165 A0A4W2D165 RACGAP1 RACGAP1 BBS4 BBS4 RHOC RHOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHMP5Charged multivesicular body protein 5. (219 aa)
A0A4W2DA03Uncharacterized protein; Belongs to the actin family. (416 aa)
CHMP4ACharged multivesicular body protein 4A. (265 aa)
RASA1RAS p21 protein activator 1. (1044 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
CEP55Centrosomal protein 55. (463 aa)
WASHC5WASH complex subunit 5. (1198 aa)
DCTN3Dynactin subunit 3. (190 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
SNX18Sorting nexin. (626 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
ANXA11Annexin. (503 aa)
STMN1Uncharacterized protein. (295 aa)
SEPTIN14Septin 14; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (432 aa)
BIN3Bridging integrator 3. (253 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
SPIRE2Spire type actin nucleation factor 2. (763 aa)
RHOARas homolog family member A. (193 aa)
SNX33Sorting nexin. (571 aa)
JTBJumping translocation breakpoint. (146 aa)
TMEM250Transmembrane protein 250. (139 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
SONSON DNA binding protein. (2455 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (888 aa)
A0A4W2EWR2Histone domain-containing protein. (110 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (438 aa)
CHMP7Charged multivesicular body protein 7. (450 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2531 aa)
MITD1Microtubule interacting and trafficking domain containing 1. (228 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1084 aa)
ANLNAnillin actin binding protein. (1129 aa)
RHOBRas homolog family member B. (181 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
STAMBPSTAM binding protein. (424 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
PLECPlectin. (4671 aa)
NUSAP1Uncharacterized protein. (465 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (488 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (406 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
RAB35RAB35, member RAS oncogene family. (263 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (667 aa)
INCENPInner centromere protein. (877 aa)
CKAP2Cytoskeleton associated protein 2. (674 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (530 aa)
A0A4W2DQW9Histone domain-containing protein. (126 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (315 aa)
ALKBH4AlkB homolog 4, lysine demethylase. (303 aa)
A0A4W2DJN4Uncharacterized protein; Belongs to the actin family. (356 aa)
ACTR3Uncharacterized protein; Belongs to the actin family. (418 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (366 aa)
ECT2Epithelial cell transforming 2. (944 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (385 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
PDCD6IPBRO1 domain-containing protein. (875 aa)
SEPTIN4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (477 aa)
SPIRE1Spire type actin nucleation factor 1. (781 aa)
CENPAHistone domain-containing protein. (138 aa)
KLHDC8BKelch domain containing 8B. (354 aa)
EFHC2EF-hand domain containing 2. (719 aa)
EFHC1EF-hand domain containing 1. (640 aa)
ARL3ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (189 aa)
A0A4W2C4H3Uncharacterized protein. (368 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
TRIM36Tripartite motif containing 36. (739 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (585 aa)
APCAPC regulator of WNT signaling pathway. (2912 aa)
SHCBP1LSHC binding and spindle associated 1 like. (651 aa)
CHMP4CCharged multivesicular body protein 4C. (236 aa)
SEPTIN3Septin 3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (799 aa)
A0A4W2CHR1Histone domain-containing protein. (127 aa)
SEPTIN10Septin 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (491 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
CUL7Cullin 7; Belongs to the cullin family. (1701 aa)
KLHDC8AKelch domain containing 8A. (257 aa)
CNTROBCentrobin, centriole duplication and spindle assembly protein. (908 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (613 aa)
IST1IST1 factor associated with ESCRT-III. (364 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1469 aa)
SNX9Sorting nexin. (624 aa)
A0A4W2D165Histone domain-containing protein. (137 aa)
RACGAP1Rac GTPase activating protein 1. (651 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
RHOCRas homolog family member C. (193 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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