STRINGSTRING
SMUG1 SMUG1 MLLT1 MLLT1 EZR EZR AKNA AKNA NFIB NFIB HERC4 HERC4 RSAD2 RSAD2 POLR1E POLR1E SAMD4A SAMD4A ORC6 ORC6 SPATA2 SPATA2 TRIM27 TRIM27 RPP38 RPP38 EEF1D EEF1D NOP58 NOP58 TERF1 TERF1 NOP53 NOP53 AGER AGER CD3EAP CD3EAP DAB2 DAB2 PAFAH1B2 PAFAH1B2 UTP4 UTP4 ACACA ACACA RPAIN RPAIN SMARCA5 SMARCA5 TAF1C TAF1C ICK ICK MALT1 MALT1 STOX1 STOX1 CCR2 CCR2 TAF4B TAF4B ESRRA ESRRA CD2BP2 CD2BP2 A0A4W2BRS1 A0A4W2BRS1 EXOSC8 EXOSC8 NUFIP1 NUFIP1 CC2D1A CC2D1A POLR1C POLR1C CD2AP CD2AP IP6K1 IP6K1 CHCHD1 CHCHD1 IP6K2 IP6K2 EIF3L EIF3L THAP1 THAP1 STN1 STN1 APEX2 APEX2 DCLRE1A DCLRE1A A0A4W2DT27 A0A4W2DT27 SIRT1 SIRT1 TXNRD1 TXNRD1 MRI1 MRI1 PSPC1 PSPC1 URB1 URB1 KDM4A KDM4A TCOF1 TCOF1 KIT KIT TAX1BP3 TAX1BP3 PRMT7 PRMT7 MAP3K14 MAP3K14 WDR33 WDR33 LIPA LIPA SNRPB2 SNRPB2 ARHGAP32 ARHGAP32 RREB1 RREB1 SNAI1 SNAI1 PEX14 PEX14 FBLIM1 FBLIM1 LEO1 LEO1 JAZF1 JAZF1 KLF6 KLF6 PAX5 PAX5 PAK6 PAK6 FOXA1 FOXA1 UTP15 UTP15 UBTF UBTF RAI14 RAI14 SMARCB1 SMARCB1 MTDH MTDH RAE1 RAE1 MBD6 MBD6 TIMM13 TIMM13 NFIC NFIC PLRG1 PLRG1 DEAF1 DEAF1 USO1 USO1 MCUB-2 MCUB-2 SAP30L SAP30L CDK7 CDK7 BTBD10 BTBD10 FBL FBL DDX46 DDX46 AFF4 AFF4 SESN1 SESN1 HOXB5 HOXB5 FHIT FHIT SMARCA4 SMARCA4 SMAD7 SMAD7 ANKRD1 ANKRD1 NOP56 NOP56 POLR1B POLR1B FOXJ2 FOXJ2 NOLC1 NOLC1 DUSP11 DUSP11 DCAF1 DCAF1 RERG RERG ZNF174 ZNF174 CAMK4 CAMK4 NEDD1 NEDD1 IMP4 IMP4 NUAK1 NUAK1 NRIP1 NRIP1 SELENBP1 SELENBP1 EN2 EN2 OTP OTP TIMM44 TIMM44 WDR43 WDR43 DSN1 DSN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMUG1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (295 aa)
MLLT1MLLT1 super elongation complex subunit. (649 aa)
EZREzrin. (638 aa)
AKNAAT-hook transcription factor. (1431 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
HERC4HECT and RLD domain containing E3 ubiquitin protein ligase 4. (1057 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (363 aa)
POLR1ERNA polymerase I subunit E. (419 aa)
SAMD4ASterile alpha motif domain containing 4A. (825 aa)
ORC6Origin recognition complex subunit 6. (203 aa)
SPATA2Spermatogenesis associated 2. (517 aa)
TRIM27Tripartite motif containing 27. (513 aa)
RPP38Ribonuclease P/MRP subunit p38. (282 aa)
EEF1DUncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family. (890 aa)
NOP58NOP58 ribonucleoprotein. (531 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa)
NOP53NOP53 ribosome biogenesis factor. (534 aa)
AGERAdvanced glycosylation end-product specific receptor. (416 aa)
CD3EAPCD3e molecule associated protein. (532 aa)
DAB2DAB adaptor protein 2. (779 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (238 aa)
UTP4UTP4 small subunit processome component. (686 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
RPAINRPA interacting protein. (295 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1051 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (1037 aa)
ICKIntestinal cell kinase. (628 aa)
MALT1MALT1 paracaspase. (850 aa)
STOX1Storkhead box 1. (984 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (383 aa)
TAF4BTATA-box binding protein associated factor 4b. (869 aa)
ESRRAEstrogen related receptor alpha. (486 aa)
CD2BP2CD2 cytoplasmic tail binding protein 2. (342 aa)
A0A4W2BRS1Uncharacterized protein. (205 aa)
EXOSC8Exosome component 8. (276 aa)
NUFIP1Nuclear FMR1 interacting protein 1. (492 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (995 aa)
POLR1CRNA polymerase I and III subunit C. (346 aa)
CD2APCD2 associated protein. (766 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
CHCHD1Coiled-coil-helix-coiled-coil-helix domain containing 1. (118 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
EIF3LEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (607 aa)
THAP1THAP domain containing 1. (213 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (391 aa)
APEX2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (513 aa)
DCLRE1ADNA cross-link repair 1A. (1045 aa)
A0A4W2DT27RRM domain-containing protein. (92 aa)
SIRT1Sirtuin 1. (734 aa)
TXNRD1Thioredoxin reductase 1. (609 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (390 aa)
PSPC1Paraspeckle component 1. (520 aa)
URB1URB1 ribosome biogenesis homolog. (2262 aa)
KDM4AUncharacterized protein. (1066 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1458 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
TAX1BP3Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
PRMT7Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (700 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (953 aa)
WDR33WD repeat domain 33. (1376 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (400 aa)
SNRPB2Uncharacterized protein. (225 aa)
ARHGAP32Rho GTPase activating protein 32. (2137 aa)
RREB1Ras responsive element binding protein 1. (1456 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
PEX14Peroxisomal biogenesis factor 14. (373 aa)
FBLIM1Uncharacterized protein. (378 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (668 aa)
JAZF1JAZF zinc finger 1. (252 aa)
KLF6Kruppel like factor 6. (331 aa)
PAX5Paired box 5. (391 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
FOXA1Forkhead box A1. (468 aa)
UTP15UTP15 small subunit processome component. (519 aa)
UBTFUpstream binding transcription factor. (757 aa)
RAI14Retinoic acid induced 14. (1024 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (436 aa)
MTDHMetadherin. (613 aa)
RAE1Ribonucleic acid export 1. (367 aa)
MBD6Methyl-CpG binding domain protein 6. (1007 aa)
TIMM13Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family. (95 aa)
NFICNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (569 aa)
PLRG1Pleiotropic regulator 1. (513 aa)
DEAF1DEAF1 transcription factor. (629 aa)
USO1USO1 vesicle transport factor. (965 aa)
MCUB-2H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (210 aa)
SAP30LSAP30 like. (182 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
BTBD10BTB domain containing 10. (510 aa)
FBLFibrillarin. (342 aa)
DDX46DEAD-box helicase 46. (1032 aa)
AFF4AF4/FMR2 family member 4. (1443 aa)
SESN1Sestrin 1. (551 aa)
HOXB5Homeobox B5. (269 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1639 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
NOP56NOP56 ribonucleoprotein. (596 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1079 aa)
FOXJ2Forkhead box J2. (561 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (762 aa)
DUSP11Dual specificity phosphatase 11. (331 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1507 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
ZNF174Zinc finger protein 174. (406 aa)
CAMK4Protein kinase domain-containing protein. (750 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (659 aa)
IMP4IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
NUAK1NUAK family kinase 1. (662 aa)
NRIP1Nuclear receptor interacting protein 1. (1156 aa)
SELENBP1Selenium binding protein 1. (485 aa)
EN2Homeobox protein engrailed-like. (324 aa)
OTPOrthopedia homeobox. (415 aa)
TIMM44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (459 aa)
WDR43WD repeat domain 43. (681 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (353 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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