STRINGSTRING
UMOD UMOD GREB1L GREB1L HNF1B HNF1B CTNNB1 CTNNB1 PKD1 PKD1 SOX8 SOX8 SOX9 SOX9 IRX1 IRX1 WNT9B WNT9B GDF11 GDF11 AQP1 AQP1 SPRY1 SPRY1 HOXC11 HOXC11 FGF10 FGF10 PAX8 PAX8 DLG5 DLG5 SMO SMO LHX1 LHX1 SIX2 SIX2 GREM1 GREM1 FGF8 FGF8 OSR2 OSR2 PDGFRA PDGFRA GDNF GDNF FOXJ1 FOXJ1 ID3 ID3 FRAS1 FRAS1 SHH SHH AQP2 AQP2 FMN1 FMN1 BMP4 BMP4 IRX2 IRX2 WT1 WT1 SOX17 SOX17 RDH10 RDH10 EYA1 EYA1 NF1 NF1 NPHS2 NPHS2 PAX2 PAX2 SMAD4 SMAD4 HES1 HES1 PKD2 PKD2 BMP7 BMP7 APH1A APH1A A0A4W2DBK6 A0A4W2DBK6 TCF21 TCF21 SIX1 SIX1 NKX3-1 NKX3-1 SIX4 SIX4 PTCH1 PTCH1 OSR1 OSR1 A0A4W2CYZ6 A0A4W2CYZ6 GATA3 GATA3 GLI3 GLI3 GDF6 GDF6 KIF26B KIF26B HOXA11 HOXA11 HES5 HES5 LGR4 LGR4 CALB1 CALB1 SALL1 SALL1 IRX3 IRX3 CTSH CTSH RET RET TFAP2B TFAP2B LAMB2 LAMB2 BCL2 BCL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UMODUromodulin. (643 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1965 aa)
HNF1BHNF1 homeobox B. (558 aa)
CTNNB1Catenin beta 1. (774 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
SOX8SRY-box transcription factor 8. (534 aa)
SOX9SRY-box transcription factor 9. (524 aa)
IRX1Iroquois homeobox 1. (476 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
GDF11Growth differentiation factor 11. (406 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
HOXC11Homeobox C11. (304 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
PAX8Paired box 8. (457 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1946 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
LHX1LIM homeobox 1. (406 aa)
SIX2SIX homeobox 2. (296 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (240 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
FOXJ1Forkhead box J1. (421 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4011 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
AQP2Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
FMN1Formin 1. (1419 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
IRX2Iroquois homeobox 2. (511 aa)
WT1WT1 transcription factor. (518 aa)
SOX17SRY-box transcription factor 17. (410 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (700 aa)
NF1Neurofibromin 1. (3024 aa)
NPHS2NPHS2 stomatin family member, podocin. (383 aa)
PAX2Paired box 2. (514 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
A0A4W2DBK6Uncharacterized protein. (284 aa)
TCF21Transcription factor 21. (179 aa)
SIX1SIX homeobox 1. (284 aa)
NKX3-1NK3 homeobox 1. (239 aa)
SIX4SIX homeobox 4. (786 aa)
PTCH1Patched 1. (1453 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
A0A4W2CYZ6Uncharacterized protein. (1943 aa)
GATA3GATA binding protein 3. (467 aa)
GLI3GLI family zinc finger 3. (1587 aa)
GDF6Growth differentiation factor 6. (470 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1912 aa)
HOXA11Homeobox A11. (316 aa)
HES5Hes family bHLH transcription factor 5. (227 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
CALB1Calbindin 1. (236 aa)
SALL1Spalt like transcription factor 1. (1316 aa)
IRX3Iroquois homeobox 3. (502 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1114 aa)
TFAP2BTranscription factor AP-2 beta. (488 aa)
LAMB2Laminin subunit beta 2. (1802 aa)
BCL2BCL2 apoptosis regulator. (229 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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