STRINGSTRING
ITGA5 ITGA5 A0A4W2BTS2 A0A4W2BTS2 BCAR1 BCAR1 RASGRP2 RASGRP2 A0A4W2BUZ8 A0A4W2BUZ8 DBNL DBNL MTSS2 MTSS2 DLC1 DLC1 A0A4W2C0I1 A0A4W2C0I1 NME1 NME1 SPATA13 SPATA13 PACSIN2 PACSIN2 PLEKHA1 PLEKHA1 CSPG4 CSPG4 SH2B2 SH2B2 INPP5J INPP5J PSD PSD MYO1C MYO1C SLC9A3R1 SLC9A3R1 PDXP PDXP IQGAP1 IQGAP1 LCP1 LCP1 IFIT5 IFIT5 APC APC EGFR EGFR CYTH3 CYTH3 MYO6 MYO6 HIP1R HIP1R A0A4W2CEF6 A0A4W2CEF6 CAPG CAPG SNTG1 SNTG1 KIF18A KIF18A AKT2 AKT2 FGD2 FGD2 RPS3 RPS3 ALS2 ALS2 SNX5 SNX5 TRPM7 TRPM7 FSCN3 FSCN3 KANK1 KANK1 LOC113877294 LOC113877294 TWF1 TWF1 EZR EZR DDX58 DDX58 TLR4 TLR4 TLN1 TLN1 A0A4W2DB82 A0A4W2DB82 TLN2 TLN2 S100A6 S100A6 SPRY4 SPRY4 PSD2 PSD2 INPP5K INPP5K APPL1 APPL1 FRMD4B FRMD4B APPL2 APPL2 EPS8L2 EPS8L2 A0A4W2DPK5 A0A4W2DPK5 A0A4W2DVE6 A0A4W2DVE6 ROCK1 ROCK1 AIF1 AIF1 ARHGEF2 ARHGEF2 ABCA7 ABCA7 CD2AP CD2AP BAIAP2 BAIAP2 PSD3 PSD3 A0A4W2E2V5 A0A4W2E2V5 PDPN PDPN ITGB1BP1 ITGB1BP1 A0A4W2EE88 A0A4W2EE88 JCAD JCAD ARF6 ARF6 A0A4W2EJW5 A0A4W2EJW5 PTK6 PTK6 PLA2G4F PLA2G4F PLCG1 PLCG1 LIMA1 LIMA1 PLEK PLEK A0A4W2ER55 A0A4W2ER55 ACTN1 ACTN1 A0A4W2ETW4 A0A4W2ETW4 A0A4W2EU87 A0A4W2EU87 PLEKHO1 PLEKHO1 PIP5K1A PIP5K1A A0A4W2EV91 A0A4W2EV91 ASAP3 ASAP3 THEM4 THEM4 C2CD5 C2CD5 EPS8 EPS8 MYH9 MYH9 EPB41L5 EPB41L5 S100B S100B WWC1 WWC1 RAB5A RAB5A MYO10 MYO10 PLCG2 PLCG2 ITGAV ITGAV WASF2 WASF2 FGR FGR RHOA RHOA SRC SRC CDK6 CDK6 EPS8L3 EPS8L3 EEF1A1 EEF1A1 FSCN1 FSCN1 ITGB1 ITGB1 SH3YL1 SH3YL1 FAP FAP MKLN1 MKLN1 ACAP2 ACAP2 MTMR14 MTMR14 PPP1R9B PPP1R9B NF2 NF2 AIF1L AIF1L CFL1 CFL1 RINL RINL TLNRD1 TLNRD1 MYO5A MYO5A CIB3 CIB3 PAK1 PAK1 CIB1 CIB1 ADAM17 ADAM17 MYADM MYADM EPS8L1 EPS8L1 CTTN CTTN VIL1 VIL1 ATP6V1B2 ATP6V1B2 RASA1 RASA1 A0A4W2ILH9 A0A4W2ILH9 KNSTRN KNSTRN ARHGAP18 ARHGAP18 SPRY2 SPRY2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1164 aa)
A0A4W2BTS2Tr-type G domain-containing protein. (432 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (919 aa)
RASGRP2RAS guanyl releasing protein 2. (608 aa)
A0A4W2BUZ8Uncharacterized protein. (402 aa)
DBNLDrebrin like. (503 aa)
MTSS2MTSS I-BAR domain containing 2. (852 aa)
DLC1DLC1 Rho GTPase activating protein. (1169 aa)
A0A4W2C0I1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (467 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
SPATA13Uncharacterized protein. (1260 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (445 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2319 aa)
SH2B2SH2B adaptor protein 2. (669 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (980 aa)
PSDPleckstrin and Sec7 domain containing. (1026 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (368 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1710 aa)
LCP1Lymphocyte cytosolic protein 1. (643 aa)
IFIT5Interferon induced protein with tetratricopeptide repeats 5. (482 aa)
APCAPC regulator of WNT signaling pathway. (2912 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
CYTH3Cytohesin 3. (418 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
HIP1RHuntingtin interacting protein 1 related. (1066 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
CAPGCapping actin protein, gelsolin like. (412 aa)
SNTG1Syntrophin gamma 1. (547 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (893 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (656 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1656 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (410 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1866 aa)
FSCN3Fascin. (497 aa)
KANK1KN motif and ankyrin repeat domains 1. (1384 aa)
LOC113877294Myotubularin phosphatase domain-containing protein. (543 aa)
TWF1Twinfilin actin binding protein 1. (368 aa)
EZREzrin. (638 aa)
DDX58DExD/H-box helicase 58. (941 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (841 aa)
TLN1Talin 1. (2539 aa)
A0A4W2DB82Tr-type G domain-containing protein. (120 aa)
TLN2Talin 2. (2542 aa)
S100A6Protein S100; Belongs to the S-100 family. (96 aa)
SPRY4Sprouty RTK signaling antagonist 4. (321 aa)
PSD2Pleckstrin and Sec7 domain containing 2. (781 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (449 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
FRMD4BFERM domain containing 4B. (1063 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (659 aa)
EPS8L2EPS8 like 2. (713 aa)
A0A4W2DPK5Tr-type G domain-containing protein. (458 aa)
A0A4W2DVE6Uncharacterized protein. (870 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1223 aa)
ABCA7ATP binding cassette subfamily A member 7. (2152 aa)
CD2APCD2 associated protein. (766 aa)
BAIAP2BAI1 associated protein 2. (568 aa)
PSD3Pleckstrin and Sec7 domain containing 3. (1253 aa)
A0A4W2E2V5Uncharacterized protein. (424 aa)
PDPNUncharacterized protein. (169 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
A0A4W2EE88Uncharacterized protein. (509 aa)
JCADJunctional cadherin 5 associated. (1305 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
A0A4W2EJW5GTP_EFTU_D3 domain-containing protein. (241 aa)
PTK6Tyrosine-protein kinase. (450 aa)
PLA2G4FPhospholipase A2. (845 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
LIMA1LIM domain and actin binding 1. (761 aa)
PLEKPleckstrin. (348 aa)
A0A4W2ER55Tr-type G domain-containing protein. (120 aa)
ACTN1Actinin alpha 1. (962 aa)
A0A4W2ETW4Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (474 aa)
A0A4W2EU87Uncharacterized protein. (226 aa)
PLEKHO1Pleckstrin homology domain containing O1. (409 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
A0A4W2EV91Uncharacterized protein. (227 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (883 aa)
THEM4Thioesterase superfamily member 4. (254 aa)
C2CD5C2 calcium dependent domain containing 5. (1137 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (836 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (726 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
WWC1WW and C2 domain containing 1. (1110 aa)
RAB5AUncharacterized protein. (215 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
WASF2WASP family member 2. (493 aa)
FGRTyrosine-protein kinase. (527 aa)
RHOARas homolog family member A. (193 aa)
SRCTyrosine-protein kinase. (559 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
EPS8L3EPS8 like 3. (592 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
FSCN1Fascin. (493 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
SH3YL1SH3 and SYLF domain containing 1. (374 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
MKLN1Muskelin 1. (735 aa)
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (824 aa)
MTMR14Myotubularin related protein 14. (649 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (817 aa)
NF2Neurofibromin 2. (596 aa)
AIF1LAllograft inflammatory factor 1 like. (252 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
RINLRas and Rab interactor like. (562 aa)
TLNRD1Talin rod domain containing 1. (362 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
CIB3Calcium and integrin binding family member 3. (187 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
CIB1Calcium and integrin binding 1. (191 aa)
ADAM17ADAM metallopeptidase domain 17. (825 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
EPS8L1EPS8 like 1. (784 aa)
CTTNCortactin. (538 aa)
VIL1Villin 1. (827 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
RASA1RAS p21 protein activator 1. (1044 aa)
A0A4W2ILH9Uncharacterized protein. (72 aa)
KNSTRNUncharacterized protein. (238 aa)
ARHGAP18Rho GTPase activating protein 18. (665 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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