40 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
	FETUB	Uncharacterized protein. (705 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	PPM1F	Protein phosphatase, Mg2+/Mn2+ dependent 1F. (672 aa)
	CCL25	SCY domain-containing protein. (235 aa)
	RIN2	Ras and Rab interactor 2. (909 aa)
	S100A10	S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
	JUP	Junction plakoglobin. (745 aa)
	CIB1	Calcium and integrin binding 1. (191 aa)
	CDH13	Cadherin 13. (713 aa)
	PLEKHA2	Pleckstrin homology domain containing A2. (425 aa)
	THY1	Thy-1 cell surface antigen. (161 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (432 aa)
	TEK	TEK receptor tyrosine kinase. (1125 aa)
	COL16A1	Collagen type XVI alpha 1 chain. (1625 aa)
	ABL1	Tyrosine-protein kinase. (1151 aa)
	CCL21	C-C motif chemokine ligand 21. (133 aa)
	RRAS	RAS related. (218 aa)
	CDK6	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (726 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
	CSF1	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (575 aa)
	EPHA1	EPH receptor A1. (1076 aa)
	FMN1	Formin 1. (1419 aa)
	UTRN	Utrophin. (3432 aa)
	FERMT1	Fermitin family member 1. (711 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	CCL28	C-C motif chemokine. (127 aa)
	PTPRJ	Peptidylprolyl isomerase. (1344 aa)
	FERMT2	Fermitin family member 2. (706 aa)
	FUT1	L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (416 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
	MYOC	Myocilin. (490 aa)
	EFEMP2	EGF containing fibulin extracellular matrix protein 2. (443 aa)
	SFRP1	Secreted frizzled related protein 1. (307 aa)
	TSC1	TSC complex subunit 1. (1165 aa)
	A0A4W2CEF6	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	A0A4W2C190	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (281 aa)
	SKAP1	Src kinase associated phosphoprotein 1. (380 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2CEF6	FERMT1	A0A4W2CEF6	A0A4W2EL82	Integrin beta; Belongs to the integrin beta chain family.	Fermitin family member 1.	0.540
A0A4W2CEF6	FERMT2	A0A4W2CEF6	A0A4W2CRF8	Integrin beta; Belongs to the integrin beta chain family.	Fermitin family member 2.	0.755
A0A4W2CEF6	ITGB1BP1	A0A4W2CEF6	A0A4W2ED50	Integrin beta; Belongs to the integrin beta chain family.	Integrin subunit beta 1 binding protein 1.	0.429
A0A4W2CEF6	KDR	A0A4W2CEF6	A0A4W2D952	Integrin beta; Belongs to the integrin beta chain family.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.673
A0A4W2CEF6	PTK2B	A0A4W2CEF6	A0A4W2EUD9	Integrin beta; Belongs to the integrin beta chain family.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.664
A0A4W2CEF6	ROCK1	A0A4W2CEF6	A0A4W2DWD9	Integrin beta; Belongs to the integrin beta chain family.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.569
A0A4W2CEF6	THY1	A0A4W2CEF6	A0A4W2BTL3	Integrin beta; Belongs to the integrin beta chain family.	Thy-1 cell surface antigen.	0.417
A0A4W2CEF6	VEGFA	A0A4W2CEF6	A0A4W2DZX0	Integrin beta; Belongs to the integrin beta chain family.	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family.	0.425
ABL1	EPHA1	A0A4W2CTP7	A0A4W2ES08	Tyrosine-protein kinase.	EPH receptor A1.	0.917
ABL1	JUP	A0A4W2CTP7	A0A4W2IRN6	Tyrosine-protein kinase.	Junction plakoglobin.	0.530
CCL21	CCL25	A0A4W2HZ99	A0A4W2D357	C-C motif chemokine ligand 21.	SCY domain-containing protein.	0.772
CCL21	CCL28	A0A4W2HZ99	A0A4W2EA59	C-C motif chemokine ligand 21.	C-C motif chemokine.	0.943
CCL25	CCL21	A0A4W2D357	A0A4W2HZ99	SCY domain-containing protein.	C-C motif chemokine ligand 21.	0.772
CCL25	CCL28	A0A4W2D357	A0A4W2EA59	SCY domain-containing protein.	C-C motif chemokine.	0.495
CCL28	CCL21	A0A4W2EA59	A0A4W2HZ99	C-C motif chemokine.	C-C motif chemokine ligand 21.	0.943
CCL28	CCL25	A0A4W2EA59	A0A4W2D357	C-C motif chemokine.	SCY domain-containing protein.	0.495
CDH13	JUP	A0A4W2BYQ0	A0A4W2IRN6	Cadherin 13.	Junction plakoglobin.	0.646
COL16A1	EFEMP2	A0A4W2CWD0	A0A4W2DX55	Collagen type XVI alpha 1 chain.	EGF containing fibulin extracellular matrix protein 2.	0.458
CSF1	KDR	A0A4W2ES30	A0A4W2D952	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...]	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.865
CSF1	TEK	A0A4W2ES30	A0A4W2CXK1	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...]	TEK receptor tyrosine kinase.	0.871

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