STRINGSTRING
ADI1 ADI1 A0A4W2BPW1 A0A4W2BPW1 A0A4W2BQA9 A0A4W2BQA9 CYP2R1 CYP2R1 SAAL1 SAAL1 A0A4W2BT40 A0A4W2BT40 LTF LTF HEPH HEPH CRTAP CRTAP SERGEF SERGEF MIOX MIOX ALKBH8 ALKBH8 PHF8 PHF8 LOC113892154 LOC113892154 A0A4W2C0J3 A0A4W2C0J3 CYP2E1 CYP2E1 LOC113884563 LOC113884563 SCD SCD CYP21A2 CYP21A2 A0A4W2C3M7 A0A4W2C3M7 A0A4W2C3P4 A0A4W2C3P4 LOC113883408 LOC113883408 A0A4W2C5B8 A0A4W2C5B8 ALOXE3 ALOXE3 ISCU ISCU ALKBH2 ALKBH2 A0A4W2C612 A0A4W2C612 CYGB CYGB CH25H CH25H FTL FTL ALOX12B ALOX12B ALOX15B ALOX15B CYP2W1 CYP2W1 SC5D SC5D ALOX15 ALOX15 KDM3A KDM3A P4HA1 P4HA1 A0A4W2CDP9 A0A4W2CDP9 LOC113876480 LOC113876480 CYP1A2 CYP1A2 CYP39A1 CYP39A1 AOX1 AOX1 LOC113876483 LOC113876483 ETHE1 ETHE1 LOC113884309 LOC113884309 A0A4W2CLE3 A0A4W2CLE3 ALKBH3 ALKBH3 CYP27A1 CYP27A1 CYP24A1 CYP24A1 XDH XDH CCNDBP1 CCNDBP1 CYP11A1 CYP11A1 ACO1 ACO1 A0A4W2D252 A0A4W2D252 CYP7B1 CYP7B1 P3H2 P3H2 NFU1 NFU1 KDM7A KDM7A FTMT FTMT MELTF MELTF DOHH DOHH SCD5 SCD5 A0A4W2BNE6 A0A4W2BNE6 FBXL5 FBXL5 TPH2 TPH2 CYP4B1 CYP4B1 PPEF2 PPEF2 CYP4F22 CYP4F22 A0A4W2DEN7 A0A4W2DEN7 LOC113889809 LOC113889809 A0A4W2DFR9 A0A4W2DFR9 RIOX2 RIOX2 LOC113889930 LOC113889930 METTL26 METTL26 CYP8B1 CYP8B1 A0A4W2DQ91 A0A4W2DQ91 A0A4W2DQP0 A0A4W2DQP0 LOC113883746 LOC113883746 A0A4W2DQS6 A0A4W2DQS6 A0A4W2DQS9 A0A4W2DQS9 PIGS PIGS HIF1AN HIF1AN A0A4W2DVL4 A0A4W2DVL4 A0A4W2DWB8 A0A4W2DWB8 CYP4X1 CYP4X1 P4HTM P4HTM TTI2 TTI2 CDO1 CDO1 LOC113884536 LOC113884536 A0A4W2E2H5 A0A4W2E2H5 A0A4W2E2T7 A0A4W2E2T7 A0A4W2E4A4 A0A4W2E4A4 P3H3 P3H3 OGFOD3 OGFOD3 TH TH A0A4W2E7K5 A0A4W2E7K5 LOC113883300 LOC113883300 A0A4W2E8A6 A0A4W2E8A6 OGFOD1 OGFOD1 CYP1A1 CYP1A1 DNAJC24 DNAJC24 A0A4W2EA75 A0A4W2EA75 CYP2F1 CYP2F1 FA2H FA2H FXN FXN P4HA3 P4HA3 ACO2 ACO2 CYP1B1 CYP1B1 CYP26B1 CYP26B1 A0A4W2EGW5 A0A4W2EGW5 PTGIS PTGIS PLOD1 PLOD1 FTO FTO LCN2 LCN2 EGLN3 EGLN3 TBXAS1 TBXAS1 ALKBH1 ALKBH1 ALOX5 ALOX5 RIOX1 RIOX1 PHF2 PHF2 CYP51A1 CYP51A1 P3H1 P3H1 A0A4W2EYK2 A0A4W2EYK2 A0A4W2F007 A0A4W2F007 A0A4W2F1E3 A0A4W2F1E3 TET2 TET2 CYP2U1 CYP2U1 CYP27C1 CYP27C1 TYW5 TYW5 ACP5 ACP5 JMJD6 JMJD6 ABCE1 ABCE1 A0A4W2FHL7 A0A4W2FHL7 CYP27B1 CYP27B1 BBOX1 BBOX1 CYP19A1 CYP19A1 CYP46A1 CYP46A1 LOC113896075 LOC113896075 A0A4W2G525 A0A4W2G525 P4HA2 P4HA2 OGFOD2 OGFOD2 TET1 TET1 SNCA SNCA ADO ADO EGLN1 EGLN1 LYRM4 LYRM4 MSMO1 MSMO1 A0A4W2H7T2 A0A4W2H7T2 EIPR1 EIPR1 PLOD2 PLOD2 CYP4V2 CYP4V2 EGLN2 EGLN2 DPH3 DPH3 CYP2S1 CYP2S1 CYP7A1 CYP7A1 PAH PAH CYP26C1 CYP26C1 ALOX12 ALOX12 CYP26A1 CYP26A1 LOC113883893 LOC113883893 CYP20A1 CYP20A1 P3H4 P3H4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (241 aa)
A0A4W2BPW1Uncharacterized protein; Belongs to the cytochrome P450 family. (441 aa)
A0A4W2BQA9Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (176 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (501 aa)
SAAL1Serum amyloid A like 1. (475 aa)
A0A4W2BT40Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (292 aa)
LTFLactotransferrin; Belongs to the transferrin family. (726 aa)
HEPHHephaestin; Belongs to the multicopper oxidase family. (1157 aa)
CRTAPUncharacterized protein. (401 aa)
SERGEFUncharacterized protein. (917 aa)
MIOXUncharacterized protein. (372 aa)
ALKBH8AlkB homolog 8, tRNA methyltransferase. (681 aa)
PHF8PHD finger protein 8. (1060 aa)
LOC113892154Uncharacterized protein. (533 aa)
A0A4W2C0J3Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (509 aa)
LOC113884563Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (497 aa)
A0A4W2C3M7Uncharacterized protein; Belongs to the cytochrome P450 family. (424 aa)
A0A4W2C3P4Uncharacterized protein. (207 aa)
LOC113883408GLOBIN domain-containing protein; Belongs to the globin family. (110 aa)
A0A4W2C5B8Uncharacterized protein; Belongs to the cytochrome P450 family. (538 aa)
ALOXE3Arachidonate lipoxygenase 3. (711 aa)
ISCUNifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)
ALKBH2AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (278 aa)
A0A4W2C612Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
CYGBCytoglobin; Belongs to the globin family. (190 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (270 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (699 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (677 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (491 aa)
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (359 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
KDM3ALysine demethylase 3A. (1340 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha 1. (534 aa)
A0A4W2CDP9FAD-binding PCMH-type domain-containing protein. (1333 aa)
LOC113876480Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (486 aa)
AOX1Aldehyde oxidase 1. (1340 aa)
LOC113876483Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
ETHE1ETHE1 persulfide dioxygenase. (259 aa)
LOC113884309PHB domain-containing protein; Belongs to the cytochrome P450 family. (598 aa)
A0A4W2CLE3Uncharacterized protein. (424 aa)
ALKBH3AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase. (286 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (541 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (561 aa)
XDHXanthine dehydrogenase. (1332 aa)
CCNDBP1Cyclin D1 binding protein 1. (358 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (536 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (897 aa)
A0A4W2D252Fe-S_biosyn domain-containing protein. (320 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (510 aa)
P3H2Prolyl 3-hydroxylase 2. (705 aa)
NFU1NFU1 iron-sulfur cluster scaffold. (254 aa)
KDM7ALysine demethylase 7A. (942 aa)
FTMTFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (242 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (739 aa)
DOHHDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (405 aa)
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (335 aa)
A0A4W2BNE6BH4_AAA_HYDROXYL_2 domain-containing protein. (571 aa)
FBXL5F-box and leucine rich repeat protein 5. (750 aa)
TPH2Tryptophan hydroxylase 2. (491 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (753 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa)
A0A4W2DEN7Uncharacterized protein. (913 aa)
LOC113889809Uncharacterized protein. (829 aa)
A0A4W2DFR9Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (157 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (535 aa)
LOC113889930Uncharacterized protein. (906 aa)
METTL26Methyltransferase like 26. (204 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (499 aa)
A0A4W2DQ91Uncharacterized protein. (474 aa)
A0A4W2DQP0Uncharacterized protein. (503 aa)
LOC113883746Uncharacterized protein. (504 aa)
A0A4W2DQS6Uncharacterized protein. (398 aa)
A0A4W2DQS9Uncharacterized protein. (374 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (641 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (349 aa)
A0A4W2DVL4Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
A0A4W2DWB8Uncharacterized protein; Belongs to the cytochrome P450 family. (525 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (515 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (494 aa)
TTI2TELO2 interacting protein 2. (531 aa)
CDO1Cysteine dioxygenase. (270 aa)
LOC113884536Uncharacterized protein; Belongs to the cytochrome P450 family. (510 aa)
A0A4W2E2H5Uncharacterized protein. (67 aa)
A0A4W2E2T7Uncharacterized protein. (159 aa)
A0A4W2E4A4Uncharacterized protein. (503 aa)
P3H3Prolyl 3-hydroxylase 3. (751 aa)
OGFOD32-oxoglutarate and iron dependent oxygenase domain containing 3. (315 aa)
THBH4_AAA_HYDROXYL_2 domain-containing protein. (536 aa)
A0A4W2E7K5Uncharacterized protein. (657 aa)
LOC113883300GLOBIN domain-containing protein; Belongs to the globin family. (292 aa)
A0A4W2E8A6Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (190 aa)
OGFOD12-oxoglutarate and iron dependent oxygenase domain containing 1. (603 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (516 aa)
DNAJC24DnaJ heat shock protein family (Hsp40) member C24. (210 aa)
A0A4W2EA75FAD-binding PCMH-type domain-containing protein. (1341 aa)
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (550 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
FXNFrataxin. (236 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha 3. (544 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
A0A4W2EGW5NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (165 aa)
PTGISProstaglandin I2 synthase. (543 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1. (726 aa)
FTOFTO alpha-ketoglutarate dependent dioxygenase. (521 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (200 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
RIOX1Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (667 aa)
PHF2PHD finger protein 2. (1091 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (510 aa)
P3H1Prolyl 3-hydroxylase 1. (736 aa)
A0A4W2EYK2Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
A0A4W2F007Uncharacterized protein; Belongs to the cytochrome P450 family. (564 aa)
A0A4W2F1E3Uncharacterized protein. (114 aa)
TET2Tet methylcytosine dioxygenase 2. (2007 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (543 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (537 aa)
TYW5tRNA-yW synthesizing protein 5. (315 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (343 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
ABCE1ATP binding cassette subfamily E member 1. (599 aa)
A0A4W2FHL7NifU_N domain-containing protein. (136 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
BBOX1Gamma-butyrobetaine hydroxylase 1. (387 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (516 aa)
LOC113896075Uncharacterized protein. (572 aa)
A0A4W2G525Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha 2. (535 aa)
OGFOD22-oxoglutarate and iron dependent oxygenase domain containing 2. (350 aa)
TET1Tet methylcytosine dioxygenase 1. (2137 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
ADO2-aminoethanethiol dioxygenase. (270 aa)
EGLN1Uncharacterized protein. (420 aa)
LYRM4Uncharacterized protein; Belongs to the complex I LYR family. (91 aa)
MSMO1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa)
A0A4W2H7T2Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (91 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (388 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (792 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (527 aa)
EGLN2Egl-9 family hypoxia inducible factor 2. (464 aa)
DPH3Diphthamide biosynthesis 3. (82 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (494 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (500 aa)
PAHPhenylalanine hydroxylase. (451 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (523 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (676 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
LOC113883893GLOBIN domain-containing protein; Belongs to the globin family. (142 aa)
CYP20A1Cytochrome P450 family 20 subfamily A member 1. (468 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (442 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: low (16%) [HD]