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F2R F2R KIF18A KIF18A NEU3 NEU3 A0A4W2CIR7 A0A4W2CIR7 CAV2 CAV2 CAV1 CAV1 SLC8A1 SLC8A1 A0A4W2CN33 A0A4W2CN33 VAMP2 VAMP2 MAPK1 MAPK1 SELE SELE CDH1 CDH1 SMPD2 SMPD2 LRRK2 LRRK2 CAVIN3 CAVIN3 NOS3 NOS3 PTCH1 PTCH1 LRP6 LRP6 TRPC4 TRPC4 ADRA1B ADRA1B KCNMA1 KCNMA1 LRP8 LRP8 SCARB1 SCARB1 CTNNA1 CTNNA1 SRC SRC TFPI TFPI LDLR LDLR CD36 CD36 PLVAP PLVAP A0A4W2EV68 A0A4W2EV68 CDHR2 CDHR2 CAVIN4 CAVIN4 PTGIS PTGIS LAMP1 LAMP1 BMPR2 BMPR2 LIPE LIPE CBL CBL TGFBR2 TGFBR2 CORO1C CORO1C FLOT2 FLOT2 BVES BVES A0A4W2BNB0 A0A4W2BNB0 CDH15 CDH15 CLN3 CLN3 STX4 STX4 HTR2A HTR2A ADRA1A ADRA1A SMO SMO SLC6A3 SLC6A3 HCK HCK CAV3 CAV3 AQP1 AQP1 FLOT1 FLOT1 MAPK3 MAPK3 EHD2 EHD2 INSR INSR CTNNB1 CTNNB1 ADTRP ADTRP DLC1 DLC1 BMPR1A BMPR1A MLC1 MLC1 CDH13 CDH13 PACSIN2 PACSIN2 RANGRF RANGRF PLPP1 PLPP1 CAVIN1 CAVIN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (893 aa)
NEU3Neuraminidase 3. (495 aa)
A0A4W2CIR7Uncharacterized protein. (379 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
A0A4W2CN33Neutral ceramidase. (786 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (118 aa)
MAPK1Mitogen-activated protein kinase. (634 aa)
SELESelectin E. (510 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (614 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
CAVIN3Caveolae associated protein 3. (260 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
PTCH1Patched 1. (1453 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1644 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (984 aa)
ADRA1BAdrenoceptor alpha 1B. (515 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1276 aa)
LRP8LDL receptor related protein 8. (1011 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (586 aa)
CTNNA1Catenin alpha 1. (919 aa)
SRCTyrosine-protein kinase. (559 aa)
TFPITissue factor pathway inhibitor. (312 aa)
LDLRLow density lipoprotein receptor. (845 aa)
CD36CD36 molecule; Belongs to the CD36 family. (486 aa)
PLVAPPlasmalemma vesicle associated protein. (442 aa)
A0A4W2EV68acidPPc domain-containing protein. (458 aa)
CDHR2Cadherin related family member 2. (1311 aa)
CAVIN4Caveolae associated protein 4. (362 aa)
PTGISProstaglandin I2 synthase. (543 aa)
LAMP1Lysosomal associated membrane protein 1. (409 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LIPELipase E, hormone sensitive type. (802 aa)
CBLCbl proto-oncogene. (932 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (493 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
BVESBlood vessel epicardial substance. (366 aa)
A0A4W2BNB0Uncharacterized protein. (146 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (870 aa)
CLN3Battenin. (460 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (447 aa)
HTR2A5-hydroxytryptamine receptor 2A. (470 aa)
ADRA1AAdrenoceptor alpha 1A. (524 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
HCKTyrosine-protein kinase. (558 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
CTNNB1Catenin beta 1. (774 aa)
ADTRPAndrogen dependent TFPI regulating protein. (230 aa)
DLC1DLC1 Rho GTPase activating protein. (1169 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MLC1Modulator of VRAC current 1. (378 aa)
CDH13Cadherin 13. (713 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (445 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
PLPP1Phospholipid phosphatase 1. (286 aa)
CAVIN1Caveolae associated protein 1. (456 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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