(46 nodes) Homologous chromosome pairing at meiosis network (Bos indicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYCE1	Synaptonemal complex central element protein 1. (400 aa)
	MRE11	MRE11 homolog, double strand break repair nuclease; Belongs to the MRE11/RAD32 family. (943 aa)
	BRIP1	BRCA1 interacting protein C-terminal helicase 1. (1172 aa)
	A0A4W2BQE8	Uncharacterized protein. (186 aa)
	STAG3	Stromal antigen 3. (1362 aa)
	CCNB1IP1	Cyclin B1 interacting protein 1. (277 aa)
	C3H1orf146	Uncharacterized protein. (181 aa)
	CCDC155	Coiled-coil domain containing 155. (565 aa)
	HORMAD1	HORMA domain containing 1. (392 aa)
	SYCP1	Synaptonemal complex protein 1. (980 aa)
	TEX15	Testis expressed 15, meiosis and synapsis associated. (2864 aa)
	MEIOC	Meiosis specific with coiled-coil domain. (960 aa)
	C14orf39	Chromosome 14 open reading frame 39. (466 aa)
	NDC1	NDC1 transmembrane nucleoporin. (784 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (427 aa)
	MEIOB	Meiosis specific with OB-fold. (472 aa)
	MEI4	Meiotic double-stranded break formation protein 4. (388 aa)
	MSH4	MutS homolog 4. (934 aa)
	ZCWPW1	Zinc finger CW-type and PWWP domain containing 1. (644 aa)
	A0A4W2DR27	Uncharacterized protein. (293 aa)
	CCDC36	Coiled-coil domain containing 36. (592 aa)
	FANCD2	FA complementation group D2. (1446 aa)
	MAJIN	Uncharacterized protein. (179 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (411 aa)
	SIRT7	Sirtuin 7. (420 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (404 aa)
	ANKRD31	Ankyrin repeat domain 31. (1940 aa)
	SUN1	Sad1 and UNC84 domain containing 1. (885 aa)
	BAG6	BCL2 associated athanogene 6. (1164 aa)
	MSH5	DNA_MISMATCH_REPAIR_2 domain-containing protein. (832 aa)
	A0A4W2EQA4	RING-type domain-containing protein. (225 aa)
	RNF212B	Ring finger protein 212B. (300 aa)
	MLH3	MutL homolog 3. (1514 aa)
	REC8	REC8 meiotic recombination protein. (579 aa)
	UBE2B	Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
	SYCE2	Synaptonemal complex central element protein 2. (214 aa)
	TERB2	Telomere repeat binding bouquet formation protein 2. (221 aa)
	RAD21L1	RAD21 cohesin complex component like 1. (555 aa)
	TEX11	Testis expressed 11. (918 aa)
	DMC1	DNA meiotic recombinase 1; Belongs to the RecA family. (340 aa)
	PSMC3IP	PSMC3 interacting protein. (217 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (436 aa)
	SPATA22	Spermatogenesis associated 22. (408 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (728 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (395 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1389 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2DR27	SYCE2	A0A4W2DR27	A0A4W2F3G2	Uncharacterized protein.	Synaptonemal complex central element protein 2.	0.689
A0A4W2EQA4	MLH3	A0A4W2EQA4	A0A4W2ERG1	RING-type domain-containing protein.	MutL homolog 3.	0.568
A0A4W2EQA4	MSH4	A0A4W2EQA4	A0A4W2DN36	RING-type domain-containing protein.	MutS homolog 4.	0.719
A0A4W2EQA4	REC8	A0A4W2EQA4	A0A4W2ERW5	RING-type domain-containing protein.	REC8 meiotic recombination protein.	0.631
A0A4W2EQA4	SPO11	A0A4W2EQA4	A0A4W2CX86	RING-type domain-containing protein.	SPO11 initiator of meiotic double stranded breaks.	0.527
A0A4W2EQA4	TEX11	A0A4W2EQA4	A0A4W2IGU0	RING-type domain-containing protein.	Testis expressed 11.	0.635
ANKRD31	HORMAD1	A0A4W2C8B4	A0A4W2D792	Ankyrin repeat domain 31.	HORMA domain containing 1.	0.461
ANKRD31	MAJIN	A0A4W2C8B4	A0A4W2DV73	Ankyrin repeat domain 31.	Uncharacterized protein.	0.473
ANKRD31	MEI4	A0A4W2C8B4	A0A4W2CC45	Ankyrin repeat domain 31.	Meiotic double-stranded break formation protein 4.	0.487
ANKRD31	MSH4	A0A4W2C8B4	A0A4W2DN36	Ankyrin repeat domain 31.	MutS homolog 4.	0.415
ANKRD31	SPO11	A0A4W2C8B4	A0A4W2CX86	Ankyrin repeat domain 31.	SPO11 initiator of meiotic double stranded breaks.	0.482
ANKRD31	SYCE1	A0A4W2C8B4	A0A4W2C351	Ankyrin repeat domain 31.	Synaptonemal complex central element protein 1.	0.597
ANKRD31	SYCE2	A0A4W2C8B4	A0A4W2F3G2	Ankyrin repeat domain 31.	Synaptonemal complex central element protein 2.	0.403
ANKRD31	SYCP1	A0A4W2C8B4	A0A4W2D948	Ankyrin repeat domain 31.	Synaptonemal complex protein 1.	0.635
ANKRD31	TERB2	A0A4W2C8B4	A0A4W2G569	Ankyrin repeat domain 31.	Telomere repeat binding bouquet formation protein 2.	0.474
BRIP1	DMC1	A0A4W2BRZ4	A0A4W2IMY6	BRCA1 interacting protein C-terminal helicase 1.	DNA meiotic recombinase 1; Belongs to the RecA family.	0.500
BRIP1	FANCD2	A0A4W2BRZ4	A0A4W2DTJ3	BRCA1 interacting protein C-terminal helicase 1.	FA complementation group D2.	0.504
BRIP1	MEIOB	A0A4W2BRZ4	A0A4W2DKM5	BRCA1 interacting protein C-terminal helicase 1.	Meiosis specific with OB-fold.	0.524
BRIP1	MLH3	A0A4W2BRZ4	A0A4W2ERG1	BRCA1 interacting protein C-terminal helicase 1.	MutL homolog 3.	0.470
BRIP1	MRE11	A0A4W2BRZ4	A0A4W2BZQ2	BRCA1 interacting protein C-terminal helicase 1.	MRE11 homolog, double strand break repair nuclease; Belongs to the MRE11/RAD32 family.	0.864

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