STRINGSTRING
A0A4W2DQY6 A0A4W2DQY6 A0A4W2DTF9 A0A4W2DTF9 GIP GIP ADRA2A ADRA2A GPER1 GPER1 CHRM3 CHRM3 GPR157 GPR157 ADM ADM LOC113905044 LOC113905044 LOC113905106 LOC113905106 LOC113905107 LOC113905107 ADCYAP1 ADCYAP1 ADRA2C ADRA2C LPAR2 LPAR2 TMEM116 TMEM116 PTGIR PTGIR CXCL9 CXCL9 ADRA1A ADRA1A GIPR GIPR GCG GCG ADGRB3 ADGRB3 GNA13 GNA13 DRD1 DRD1 UCN2 UCN2 S1PR4 S1PR4 RAPGEF2 RAPGEF2 GHRH GHRH GNAQ GNAQ GPR6 GPR6 CALCRL CALCRL PTGFR PTGFR LPAR3 LPAR3 S1PR5 S1PR5 GPR161 GPR161 PTGER1 PTGER1 ADGRE3 ADGRE3 PTHLH PTHLH CALCR CALCR CXCL11 CXCL11 CXCL10 CXCL10 DRD5 DRD5 S1PR3 S1PR3 ABCA1 ABCA1 LPAR1 LPAR1 S1PR1 S1PR1 GPR65 GPR65 TSHR TSHR A0A4W2EPL5 A0A4W2EPL5 LOC113895814 LOC113895814 ADCY5 ADCY5 ADCY3 ADCY3 GPR3 GPR3 CHGA CHGA UCN3 UCN3 VIP VIP ADGRF5 ADGRF5 MC3R MC3R RAMP3 RAMP3 ADCY1 ADCY1 PTH1R PTH1R ADRA1D ADRA1D ADORA2A ADORA2A GHRHR GHRHR A0A4W2E8R7 A0A4W2E8R7 ADGRD1 ADGRD1 GNB1 GNB1 MC1R MC1R ADGRB1 ADGRB1 ADCY8 ADCY8 ADGRL4 ADGRL4 GPR26 GPR26 ADGRG3 ADGRG3 ADGRG5 ADGRG5 ADRB1 ADRB1 ADCY7 ADCY7 ADCY9 ADCY9 MC5R MC5R A0A4W2BV17 A0A4W2BV17 ADRB3 ADRB3 GNAL GNAL ADGRF1 ADGRF1 ADGRF4 ADGRF4 A0A4W2BY61 A0A4W2BY61 DRD2 DRD2 MC4R MC4R ADGRF2 ADGRF2 GPR62 GPR62 GLP1R GLP1R SLC9A3R1 SLC9A3R1 ADGRG1 ADGRG1 PLN PLN PTGER4 PTGER4 ADM2 ADM2 RXFP1 RXFP1 RAMP2 RAMP2 LHCGR LHCGR PTH PTH GCGR GCGR ADGRD2 ADGRD2 GNG2 GNG2 ADGRG6 ADGRG6 CRHR1 CRHR1 GNAS GNAS ADCY2 ADCY2 LOC113895813 LOC113895813 PTRHD1 PTRHD1 FSHR FSHR ADCY6 ADCY6 ADGRF3 ADGRF3 A0A4W2D3I1 A0A4W2D3I1 PTGER2 PTGER2 ADCY4 ADCY4 RAPGEF4 RAPGEF4 CNR2 CNR2 GPHB5 GPHB5 HTR5A HTR5A A0A4W2DFH0 A0A4W2DFH0 A0A4W2DFJ2 A0A4W2DFJ2 A0A4W2DFS7 A0A4W2DFS7 ADGRE5 ADGRE5 DRD3 DRD3 PTGER3 PTGER3 ADRA2B ADRA2B GPR12 GPR12 ADRB2 ADRB2 LOC113896427 LOC113896427 A0A4W2DLD2 A0A4W2DLD2 TBXA2R TBXA2R ADRA1B ADRA1B ADGRG7 ADGRG7 GPHA2 GPHA2 RXFP2 RXFP2 A0A4W2DQG9 A0A4W2DQG9 DRD4 DRD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4W2DQY6C-X-C motif chemokine. (138 aa)
A0A4W2DTF9C-X-C motif chemokine. (295 aa)
GIPGastric inhibitory polypeptide. (143 aa)
ADRA2AAdrenoceptor alpha 2A. (468 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (602 aa)
GPR157G protein-coupled receptor 157. (327 aa)
ADMUncharacterized protein. (456 aa)
LOC113905044Uncharacterized protein. (125 aa)
LOC113905106CALCITONIN domain-containing protein. (123 aa)
LOC113905107CALCITONIN domain-containing protein. (143 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
ADRA2CAdrenoceptor alpha 2C. (461 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
TMEM116Transmembrane protein 116. (364 aa)
PTGIRProstaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
CXCL9C-X-C motif chemokine. (125 aa)
ADRA1AAdrenoceptor alpha 1A. (524 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
GCGGlucagon. (180 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
GNA13G protein subunit alpha 13. (377 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
UCN2Urocortin 2. (112 aa)
S1PR4Sphingosine-1-phosphate receptor 4. (385 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1689 aa)
GHRHGrowth hormone releasing hormone. (106 aa)
GNAQG protein subunit alpha q. (359 aa)
GPR6G protein-coupled receptor 6; Belongs to the G-protein coupled receptor 1 family. (365 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
PTGFRG_PROTEIN_RECEP_F1_2 domain-containing protein. (362 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
S1PR5Sphingosine-1-phosphate receptor 5. (399 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (576 aa)
PTGER1Prostaglandin E receptor 1. (441 aa)
ADGRE3Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (635 aa)
PTHLHParathyroid hormone like hormone. (177 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (548 aa)
CXCL11C-X-C motif chemokine. (100 aa)
CXCL10C-X-C motif chemokine. (102 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (473 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
GPR65G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (334 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (763 aa)
A0A4W2EPL5Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1397 aa)
LOC113895814Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (660 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
GPR3G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
CHGAChromogranin A. (488 aa)
UCN3Urocortin 3. (166 aa)
VIPVasoactive intestinal peptide. (170 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1418 aa)
MC3RMelanocortin 3 receptor. (323 aa)
RAMP3Receptor activity modifying protein 3. (150 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (589 aa)
ADRA1DAdrenoceptor alpha 1D. (567 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (401 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (527 aa)
A0A4W2E8R7CALCITONIN domain-containing protein. (168 aa)
ADGRD1Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family. (902 aa)
GNB1G protein subunit beta 1. (358 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (317 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1457 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
ADGRL4Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (689 aa)
GPR26G protein-coupled receptor 26. (337 aa)
ADGRG3Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (547 aa)
ADGRG5Adhesion G protein-coupled receptor G5; Belongs to the G-protein coupled receptor 2 family. (585 aa)
ADRB1Adrenoceptor beta 1. (514 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1117 aa)
MC5RMelanocortin 5 receptor. (325 aa)
A0A4W2BV17Uncharacterized protein. (963 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (438 aa)
GNALG protein subunit alpha L. (452 aa)
ADGRF1Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (942 aa)
ADGRF4Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family. (691 aa)
A0A4W2BY61G_PROTEIN_RECEP_F1_2 domain-containing protein. (346 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
MC4RMelanocortin 4 receptor. (333 aa)
ADGRF2Adhesion G protein-coupled receptor F2; Belongs to the G-protein coupled receptor 2 family. (671 aa)
GPR62G protein-coupled receptor 62. (397 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (368 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (746 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (492 aa)
ADM2Adrenomedullin 2. (142 aa)
RXFP1Relaxin family peptide receptor 1. (786 aa)
RAMP2Receptor activity modifying protein 2. (182 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
PTHParathyroid hormone. (147 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (479 aa)
ADGRD2Adhesion G protein-coupled receptor D2; Belongs to the G-protein coupled receptor 2 family. (945 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (123 aa)
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1250 aa)
CRHR1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (435 aa)
GNASGNAS complex locus. (1004 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
LOC113895813Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (801 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
ADGRF3Adhesion G protein-coupled receptor F3; Belongs to the G-protein coupled receptor 2 family. (1097 aa)
A0A4W2D3I1Uncharacterized protein. (464 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
GPHB5Glycoprotein hormone subunit beta 5. (130 aa)
HTR5A5-hydroxytryptamine receptor 5A. (358 aa)
A0A4W2DFH0Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (652 aa)
A0A4W2DFJ2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (775 aa)
A0A4W2DFS7Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (733 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (886 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (479 aa)
PTGER3Prostaglandin E receptor 3. (389 aa)
ADRA2BAdrenoceptor alpha 2B. (475 aa)
GPR12G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (494 aa)
ADRB2Adrenoceptor beta 2. (418 aa)
LOC113896427Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (766 aa)
A0A4W2DLD2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (807 aa)
TBXA2RThromboxane A2 receptor. (343 aa)
ADRA1BAdrenoceptor alpha 1B. (515 aa)
ADGRG7Adhesion G protein-coupled receptor G7; Belongs to the G-protein coupled receptor 2 family. (795 aa)
GPHA2Glycoprotein hormone subunit alpha 2. (129 aa)
RXFP2Relaxin family peptide receptor 2. (753 aa)
A0A4W2DQG9Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (783 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (372 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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