58 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SVIL	Supervillin. (2301 aa)
	WASHC5	WASH complex subunit 5. (1198 aa)
	VIL1	Villin 1. (827 aa)
	CTTN	Cortactin. (538 aa)
	CFL1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
	TWF2	Twinfilin actin binding protein 2. (349 aa)
	FHDC1	FH2 domain containing 1. (1143 aa)
	VASP	Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
	LMOD2	Leiomodin 2. (585 aa)
	WASHC3	WASH complex subunit 3. (194 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	SPIRE2	Spire type actin nucleation factor 2. (763 aa)
	SCIN	Scinderin. (832 aa)
	WDR1	WD repeat domain 1. (606 aa)
	ENAH	ENAH actin regulator. (823 aa)
	ARPC2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
	FLII	FLII actin remodeling protein. (1268 aa)
	CATIP	Ciliogenesis associated TTC17 interacting protein. (390 aa)
	A0A4W2EEW9	Uncharacterized protein. (1936 aa)
	ABI1	Abl interactor 1. (508 aa)
	AVIL	Advillin. (816 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	A0A4W2E766	Uncharacterized protein. (73 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (1009 aa)
	ABI2	Abl interactor 2. (542 aa)
	SPATC1	Spermatogenesis and centriole associated 1. (423 aa)
	AIF1	Allograft inflammatory factor 1. (147 aa)
	WIPF1	WH2 domain-containing protein. (509 aa)
	LOC113883894	Coronin; Belongs to the WD repeat coronin family. (979 aa)
	WAS	WASP actin nucleation promoting factor. (559 aa)
	GSN	Gelsolin. (846 aa)
	A0A4W2DHL6	Uncharacterized protein. (165 aa)
	SPATC1L	Spermatogenesis and centriole associated 1 like. (343 aa)
	ANG	RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (165 aa)
	A0A4W2DHA5	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (159 aa)
	CAPZB	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (306 aa)
	DIAPH1	Diaphanous related formin 1. (1308 aa)
	WASL	WASP like actin nucleation promoting factor. (511 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
	TWF1	Twinfilin actin binding protein 1. (368 aa)
	HCLS1	Hematopoietic cell-specific Lyn substrate 1. (485 aa)
	EVL	Enah/Vasp-like. (455 aa)
	DSTN	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
	TTC17	Tetratricopeptide repeat domain 17. (1219 aa)
	PSTPIP1	Proline-serine-threonine phosphatase interacting protein 1. (496 aa)
	MSRB2	Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues. (182 aa)
	CAPG	Capping actin protein, gelsolin like. (412 aa)
	MICAL1	Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1070 aa)
	PSTPIP2	Proline-serine-threonine phosphatase interacting protein 2. (334 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (133 aa)
	ARPC4	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
	MICAL3	Microtubule associated monooxygenase, calponin and LIM domain containing 3. (2087 aa)
	GAS7	Growth arrest specific 7. (476 aa)
	MSRB1	Methionine sulfoxide reductase B1. (115 aa)
	SPIRE1	Spire type actin nucleation factor 1. (781 aa)
	VILL	Villin like. (856 aa)
	DIAPH3	Diaphanous related formin 3. (1184 aa)
	FAM107A	Family with sequence similarity 107 member A. (225 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2DHA5	A0A4W2DHL6	A0A4W2DHA5	A0A4W2DHL6	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Uncharacterized protein.	0.961
A0A4W2DHA5	ABI1	A0A4W2DHA5	A0A4W2ECU2	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Abl interactor 1.	0.886
A0A4W2DHA5	ABI2	A0A4W2DHA5	A0A4W2E526	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Abl interactor 2.	0.443
A0A4W2DHA5	ARPC4	A0A4W2DHA5	A0A4W2C638	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	0.992
A0A4W2DHA5	CAPZB	A0A4W2DHA5	A0A4W2DGI5	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.687
A0A4W2DHA5	CFL1	A0A4W2DHA5	A0A4W2HRI3	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Cofilin 1; Belongs to the actin-binding proteins ADF family.	0.455
A0A4W2DHA5	CTTN	A0A4W2DHA5	A0A4W2I9Z5	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Cortactin.	0.593
A0A4W2DHA5	HCLS1	A0A4W2DHA5	A0A4W2CY59	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	Hematopoietic cell-specific Lyn substrate 1.	0.613
A0A4W2DHA5	WAS	A0A4W2DHA5	A0A4W2DNV6	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	WASP actin nucleation promoting factor.	0.936
A0A4W2DHA5	WASL	A0A4W2DHA5	A0A4W2DC12	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	WASP like actin nucleation promoting factor.	0.943
A0A4W2DHL6	A0A4W2DHA5	A0A4W2DHL6	A0A4W2DHA5	Uncharacterized protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.961
A0A4W2DHL6	ABI1	A0A4W2DHL6	A0A4W2ECU2	Uncharacterized protein.	Abl interactor 1.	0.518
A0A4W2DHL6	ABI2	A0A4W2DHL6	A0A4W2E526	Uncharacterized protein.	Abl interactor 2.	0.405
A0A4W2DHL6	ARPC2	A0A4W2DHL6	A0A4W2EGQ6	Uncharacterized protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.961
A0A4W2DHL6	CAPZB	A0A4W2DHL6	A0A4W2DGI5	Uncharacterized protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.595
A0A4W2DHL6	WAS	A0A4W2DHL6	A0A4W2DNV6	Uncharacterized protein.	WASP actin nucleation promoting factor.	0.804
A0A4W2DHL6	WASL	A0A4W2DHL6	A0A4W2DC12	Uncharacterized protein.	WASP like actin nucleation promoting factor.	0.804
A0A4W2E766	GHSR	A0A4W2E766	A0A4W2G2N5	Uncharacterized protein.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.982
ABI1	A0A4W2DHA5	A0A4W2ECU2	A0A4W2DHA5	Abl interactor 1.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.886
ABI1	A0A4W2DHL6	A0A4W2ECU2	A0A4W2DHL6	Abl interactor 1.	Uncharacterized protein.	0.518

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