120 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRK	CRK proto-oncogene, adaptor protein. (376 aa)
	WASF3	WASP family member 3. (501 aa)
	CCL24	C-C motif chemokine ligand 24. (116 aa)
	A0A4W2BQT6	SCY domain-containing protein. (170 aa)
	A0A4W2BRS1	Uncharacterized protein. (205 aa)
	PLXND1	Plexin D1. (1930 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	ALDOA	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (416 aa)
	CFDP1	Craniofacial development protein 1. (377 aa)
	DLC1	DLC1 Rho GTPase activating protein. (1169 aa)
	PLXNB2	Plexin B2. (1985 aa)
	PARVB	Parvin beta. (365 aa)
	RHOBTB1	Rho related BTB domain containing 1. (698 aa)
	RHOU	Ras homolog family member U. (255 aa)
	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (368 aa)
	MYH10	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
	CDC42EP1	CDC42 effector protein 1. (361 aa)
	GNA12	G protein subunit alpha 12. (382 aa)
	MYL12A	Myosin light chain 12A. (178 aa)
	MYL12B	Myosin light chain 12B. (171 aa)
	PHIP	Pleckstrin homology domain interacting protein. (1822 aa)
	A0A4W2CDP2	Uncharacterized protein. (200 aa)
	A0A4W2CP79	Annexin. (335 aa)
	A0A4W2CRW3	Annexin. (346 aa)
	EPB41	Erythrocyte membrane protein band 4.1. (956 aa)
	RND1	Rho family GTPase 1. (232 aa)
	PLXNA4	Plexin A4. (1893 aa)
	C15orf62	Chromosome 15 open reading frame 62. (176 aa)
	EZR	Ezrin. (638 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
	RHOC	Ras homolog family member C. (193 aa)
	PALMD	Palmdelphin. (550 aa)
	PLXNC1	Plexin C1. (1597 aa)
	A0A4W2D873	Uncharacterized protein. (99 aa)
	A0A4W2D8A8	BTB domain-containing protein. (666 aa)
	DMTN	Dematin actin binding protein. (467 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	FAM171B	Family with sequence similarity 171 member B. (820 aa)
	RHOJ	Ras homolog family member J. (236 aa)
	STRIP2	Striatin interacting protein 2. (834 aa)
	ARHGAP15	Rho GTPase activating protein 15. (472 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	BRWD1	Bromodomain and WD repeat domain containing 1. (2323 aa)
	ARHGEF18	Uncharacterized protein. (1345 aa)
	RND3	Rho family GTPase 3. (244 aa)
	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1548 aa)
	PALM3	Paralemmin 3. (762 aa)
	SLC26A5	Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (741 aa)
	LIMD1	LIM domains containing 1. (674 aa)
	PALM	Paralemmin. (219 aa)
	CCL2	C-C motif chemokine. (99 aa)
	PLXNB1	Plexin B1. (2155 aa)
	BAIAP2	BAI1 associated protein 2. (568 aa)
	SPTA1	Spectrin alpha, erythrocytic 1. (2419 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
	RHOF	Ras homolog family member F, filopodia associated. (215 aa)
	DNMBP	Dynamin binding protein. (1579 aa)
	HPN	Hepsin; Belongs to the peptidase S1 family. (454 aa)
	BVES	Blood vessel epicardial substance. (366 aa)
	RHOQ	Ras homolog family member Q. (209 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (1009 aa)
	CDC42EP4	CDC42 effector protein 4. (351 aa)
	SYNE3	Spectrin repeat containing nuclear envelope family member 3. (1086 aa)
	FN1	Fibronectin 1. (2601 aa)
	PDPN	Uncharacterized protein. (169 aa)
	FMNL1	Formin like 1. (1169 aa)
	FAM171A2	Family with sequence similarity 171 member A2. (831 aa)
	BAMBI	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
	EPB42	Erythrocyte membrane protein band 4.2. (687 aa)
	SEPTIN7	Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (488 aa)
	F2	Coagulation factor II, thrombin; Belongs to the peptidase S1 family. (631 aa)
	FAM171A1	Family with sequence similarity 171 member A1. (897 aa)
	FBLIM1	Uncharacterized protein. (378 aa)
	PKHD1L1	PKHD1 like 1. (4245 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	RHOB	Ras homolog family member B. (181 aa)
	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1740 aa)
	FMNL3	Formin like 3. (1028 aa)
	RHOBTB3	Rho related BTB domain containing 3. (912 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	AKAP2	AKAP2_C domain-containing protein. (1333 aa)
	PEAK3	PEAK family member 3. (466 aa)
	TBCCD1	TBCC domain containing 1. (580 aa)
	WDR1	WD repeat domain 1. (606 aa)
	PLEKHO1	Pleckstrin homology domain containing O1. (409 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
	LOC113897295	Uncharacterized protein. (736 aa)
	SHROOM3	Shroom family member 3. (1988 aa)
	EPS8	Epidermal growth factor receptor pathway substrate 8. (836 aa)
	ERMN	Ermin. (282 aa)
	SEMA4A	Semaphorin 4A; Belongs to the semaphorin family. (851 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
	RAC2	Rac family small GTPase 2. (209 aa)
	CSF1R	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1046 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (763 aa)
	CFAP410	LRRcap domain-containing protein. (256 aa)
	MYO10	Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa)
	FGR	Tyrosine-protein kinase. (527 aa)
	RHOA	Ras homolog family member A. (193 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (863 aa)
	F11R	F11 receptor. (298 aa)
	CCL11	C-C motif chemokine. (97 aa)
	RHOD	Ras homolog family member D. (210 aa)
	RDX	Radixin. (624 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	PLXNA2	Plexin A2. (1894 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1500 aa)
	MKLN1	Muskelin 1. (735 aa)
	TAOK2	TAO kinase 2. (1125 aa)
	HCK	Tyrosine-protein kinase. (558 aa)
	CDC42EP3	CDC42 effector protein 3. (254 aa)
	RND2	Rho family GTPase 2. (227 aa)
	FMNL2	Formin like 2. (1100 aa)
	CDC42EP5	CDC42 effector protein 5. (153 aa)
	RHOG	Ras homolog family member G. (191 aa)
	VIL1	Villin 1. (827 aa)
	COCH	Cochlin. (550 aa)
	ARHGAP18	Rho GTPase activating protein 18. (665 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2BQT6	CCL11	A0A4W2BQT6	A0A4W2GC78	SCY domain-containing protein.	C-C motif chemokine.	0.526
A0A4W2BQT6	CCL2	A0A4W2BQT6	A0A4W2DT70	SCY domain-containing protein.	C-C motif chemokine.	0.894
A0A4W2BQT6	CSF1R	A0A4W2BQT6	A0A4W2F1H9	SCY domain-containing protein.	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.427
A0A4W2BQT6	VEGFA	A0A4W2BQT6	A0A4W2DZX0	SCY domain-containing protein.	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family.	0.402
A0A4W2D873	BAIAP2	A0A4W2D873	A0A4W2DYU9	Uncharacterized protein.	BAI1 associated protein 2.	0.478
A0A4W2D8A8	BAIAP2	A0A4W2D8A8	A0A4W2DYU9	BTB domain-containing protein.	BAI1 associated protein 2.	0.478
A0A4W2D8A8	RHOBTB1	A0A4W2D8A8	A0A4W2C0V7	BTB domain-containing protein.	Rho related BTB domain containing 1.	0.805
ARAP1	ARHGEF18	A0A4W2EK28	A0A4W2DHU4	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Uncharacterized protein.	0.440
ARAP1	FYN	A0A4W2EK28	A0A4W2EJI9	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Tyrosine-protein kinase.	0.707
ARAP3	RHOA	A0A4W2DJ64	A0A4W2FLL1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3.	Ras homolog family member A.	0.940
ARAP3	RHOB	A0A4W2DJ64	A0A4W2EJU3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3.	Ras homolog family member B.	0.813
ARAP3	RHOC	A0A4W2DJ64	A0A4W2D3R3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3.	Ras homolog family member C.	0.813
ARHGAP15	ARHGAP18	A0A4W2DDZ9	A0A4W2IRA9	Rho GTPase activating protein 15.	Rho GTPase activating protein 18.	0.468
ARHGAP15	RAC2	A0A4W2DDZ9	A0A4W2F158	Rho GTPase activating protein 15.	Rac family small GTPase 2.	0.422
ARHGAP18	ARHGAP15	A0A4W2IRA9	A0A4W2DDZ9	Rho GTPase activating protein 18.	Rho GTPase activating protein 15.	0.468
ARHGAP18	RHOA	A0A4W2IRA9	A0A4W2FLL1	Rho GTPase activating protein 18.	Ras homolog family member A.	0.576
ARHGAP18	RHOB	A0A4W2IRA9	A0A4W2EJU3	Rho GTPase activating protein 18.	Ras homolog family member B.	0.443
ARHGAP18	RHOC	A0A4W2IRA9	A0A4W2D3R3	Rho GTPase activating protein 18.	Ras homolog family member C.	0.443
ARHGAP18	RND3	A0A4W2IRA9	A0A4W2DJ19	Rho GTPase activating protein 18.	Rho family GTPase 3.	0.521
ARHGAP35	FGR	A0A4W2GRV1	A0A4W2FEE9	Rho GTPase activating protein 35.	Tyrosine-protein kinase.	0.464

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