STRINGSTRING
ATP1B3 ATP1B3 ERBB3 ERBB3 LDLR LDLR MTTP MTTP TACSTD2 TACSTD2 BSND BSND CLDN8 CLDN8 RHBG RHBG A0A4W2EY41 A0A4W2EY41 SLC2A1 SLC2A1 SLC4A4 SLC4A4 STK39 STK39 SLC39A14 SLC39A14 RAB17 RAB17 AQP3 AQP3 SLC12A2 SLC12A2 CLDN1 CLDN1 SLC51A SLC51A TSHR TSHR AQP2 AQP2 SLC22A1 SLC22A1 SLC12A6 SLC12A6 AJAP1 AJAP1 NKD2 NKD2 SLC16A10 SLC16A10 SLC23A2 SLC23A2 DSTYK DSTYK SLC41A1 SLC41A1 RHCG RHCG SLC29A4 SLC29A4 ITGB4 ITGB4 SLC22A7 SLC22A7 MYO1C MYO1C LOC113884473 LOC113884473 SLC7A1 SLC7A1 KCNJ4 KCNJ4 MST1R MST1R MLC1 MLC1 UMOD UMOD SLC4A7 SLC4A7 SLC14A1 SLC14A1 CADM1 CADM1 SLC3A2 SLC3A2 CA10 CA10 CALHM1 CALHM1 MET MET SLC6A6 SLC6A6 LOC113886271 LOC113886271 SLC22A8 SLC22A8 BEST1 BEST1 NOD2 NOD2 PDPN PDPN DSP DSP C5AR1 C5AR1 LIN7B LIN7B FLOT2 FLOT2 EPCAM EPCAM FOLR1 FOLR1 SCRIB SCRIB ADCY8 ADCY8 SLC16A12 SLC16A12 LIN7C LIN7C ORAI1 ORAI1 SLC26A7 SLC26A7 ITGA3 ITGA3 DLG3 DLG3 ERBB2 ERBB2 SLC4A9 SLC4A9 ATP7B ATP7B ABCC1 ABCC1 LPO LPO SLC51B SLC51B SLC2A9 SLC2A9 A0A4W2DN71 A0A4W2DN71 SLC26A5 SLC26A5 SLC22A5 SLC22A5 SLC19A1 SLC19A1 MYO1D MYO1D TRPC4 TRPC4 SLC9B2 SLC9B2 KCNJ10 KCNJ10 CXADR CXADR PLPP3 PLPP3 SLC40A1 SLC40A1 SLC27A1 SLC27A1 LEPR LEPR OSCP1 OSCP1 A0A4W2DEN7 A0A4W2DEN7 LDLRAP1 LDLRAP1 PKD2 PKD2 AQP7 AQP7 SLC4A10 SLC4A10 SLC4A2 SLC4A2 SLC4A11 SLC4A11 ATP2B1 ATP2B1 FRMPD2 FRMPD2 TFRC TFRC TGFA TGFA HPGD HPGD CLDN7 CLDN7 CD81 CD81 B4GALT1 B4GALT1 CHRM3 CHRM3 CNNM4 CNNM4 STX2 STX2 FLOT1 FLOT1 AQP1 AQP1 CNNM2 CNNM2 SLC22A6 SLC22A6 CLDN19 CLDN19 SLCO1C1 SLCO1C1 PDZD11 PDZD11 CA11 CA11 ERBB4 ERBB4 KCNQ1 KCNQ1 LRRC7 LRRC7 SLC39A8 SLC39A8 ABCC5 ABCC5 ATP1A1 ATP1A1 SLC29A2 SLC29A2 SLC46A1 SLC46A1 CALHM3 CALHM3 SLC23A1 SLC23A1 MYO1A MYO1A ABCC3 ABCC3 WASF2 WASF2 A0A4W2FDM7 A0A4W2FDM7 ATP6V1B1 ATP6V1B1 MUC20 MUC20 SLC39A5 SLC39A5 PKD1 PKD1 CTNNB1 CTNNB1 AQP4 AQP4 HEPH HEPH SPEF1 SPEF1 SYNJ2BP SYNJ2BP SLC13A3 SLC13A3 LIN7A LIN7A SLC43A3 SLC43A3 NUMB NUMB SLC7A8 SLC7A8 DLG1 DLG1 EZR EZR SLC38A1 SLC38A1 TEK TEK ATP1B1 ATP1B1 SLC26A10 SLC26A10 EPB41 EPB41 A0A4W2CRW3 A0A4W2CRW3 AQP9 AQP9 LRP1 LRP1 A0A4W2CP79 A0A4W2CP79 NOD1 NOD1 IDE IDE SLC27A5 SLC27A5 ABCC10 ABCC10 SLC16A8 SLC16A8 C5AR2 C5AR2 SLC29A1 SLC29A1 ALPK2 ALPK2 NDRG4 NDRG4 A0A4W2CD19 A0A4W2CD19 CDH16 CDH16 SLC4A1 SLC4A1 ABCC6 ABCC6 SLC26A6 SLC26A6 MARVELD2 MARVELD2 EGFR EGFR CDH17 CDH17 ERBIN ERBIN SLC16A3 SLC16A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1336 aa)
LDLRLow density lipoprotein receptor. (845 aa)
MTTPMicrosomal triglyceride transfer protein. (894 aa)
TACSTD2Tumor associated calcium signal transducer 2. (319 aa)
BSNDBarttin CLCNK type accessory beta subunit. (319 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
RHBGRh family B glycoprotein (gene/pseudogene); Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (455 aa)
A0A4W2EY41Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (418 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (530 aa)
SLC4A4Anion exchange protein. (1190 aa)
STK39Serine/threonine kinase 39. (681 aa)
SLC39A14Solute carrier family 39 member 14. (531 aa)
RAB17RAB17, member RAS oncogene family. (233 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
SLC12A2Solute carrier family 12 member 2. (1204 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SLC51ASolute carrier family 51 alpha subunit. (340 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (763 aa)
AQP2Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC22A1Solute carrier family 22 member 1. (563 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
AJAP1Adherens junctions associated protein 1. (416 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (483 aa)
SLC16A10Solute carrier family 16 member 10. (515 aa)
SLC23A2Solute carrier family 23 member 2. (650 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (883 aa)
SLC41A1Solute carrier family 41 member 1. (514 aa)
RHCGRh family C glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (598 aa)
SLC29A4Solute carrier family 29 member 4. (523 aa)
ITGB4Integrin beta. (1804 aa)
SLC22A7Solute carrier family 22 member 7. (547 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
LOC113884473CH_2 domain-containing protein. (271 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (444 aa)
MST1RMacrophage stimulating 1 receptor. (1401 aa)
MLC1Modulator of VRAC current 1. (378 aa)
UMODUromodulin. (643 aa)
SLC4A7Anion exchange protein. (1241 aa)
SLC14A1Urea transporter; Belongs to the urea transporter family. (450 aa)
CADM1Cell adhesion molecule 1. (478 aa)
SLC3A2Solute carrier family 3 member 2. (572 aa)
CA10Carbonic anhydrase 10; Belongs to the alpha-carbonic anhydrase family. (328 aa)
CALHM1Calcium homeostasis modulator 1. (344 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1384 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (874 aa)
LOC113886271MFS domain-containing protein. (1020 aa)
SLC22A8Solute carrier family 22 member 8. (543 aa)
BEST1Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. (643 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
PDPNUncharacterized protein. (169 aa)
DSPDesmoplakin. (2889 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
EPCAMEpithelial cell adhesion molecule. (314 aa)
FOLR1Folate receptor alpha. (287 aa)
SCRIBScribble planar cell polarity protein. (1603 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
SLC16A12Solute carrier family 16 member 12. (486 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (303 aa)
SLC26A7Anion exchange transporter. (655 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1065 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (848 aa)
ERBB2Erb-b2 receptor tyrosine kinase 2. (1710 aa)
SLC4A9Anion exchange protein. (957 aa)
ATP7BATPase copper transporting beta. (1505 aa)
ABCC1ATP binding cassette subfamily C member 1. (1544 aa)
LPOLactoperoxidase. (722 aa)
SLC51BSolute carrier family 51 beta subunit. (130 aa)
SLC2A9Solute carrier family 2 member 9; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (576 aa)
A0A4W2DN71Uncharacterized protein. (86 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (741 aa)
SLC22A5Solute carrier family 22 member 5. (557 aa)
SLC19A1Solute carrier family 19 member 1. (572 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (984 aa)
SLC9B2Solute carrier family 9 member B2. (535 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
CXADRUncharacterized protein. (403 aa)
PLPP3acidPPc domain-containing protein. (311 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (574 aa)
SLC27A1Solute carrier family 27 member 1. (676 aa)
LEPRLeptin receptor. (1165 aa)
OSCP1Organic solute carrier partner 1. (389 aa)
A0A4W2DEN7Uncharacterized protein. (913 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (310 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
AQP7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (317 aa)
SLC4A10Anion exchange protein. (1147 aa)
SLC4A2Anion exchange protein. (1276 aa)
SLC4A11Solute carrier family 4 member 11. (861 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
FRMPD2FERM and PDZ domain containing 2. (1389 aa)
TFRCTransferrin receptor. (842 aa)
TGFATransforming growth factor alpha. (228 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CD81Tetraspanin. (236 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (402 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (602 aa)
CNNM4Cyclin and CBS domain divalent metal cation transport mediator 4. (795 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (317 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
CNNM2Cyclin and CBS domain divalent metal cation transport mediator 2. (875 aa)
SLC22A6Solute carrier family 22 member 6. (550 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
SLCO1C1Solute carrier organic anion transporter family member. (712 aa)
PDZD11PDZ domain containing 11. (140 aa)
CA11Carbonic anhydrase 11; Belongs to the alpha-carbonic anhydrase family. (401 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
LRRC7Leucine rich repeat containing 7. (1594 aa)
SLC39A8Solute carrier family 39 member 8. (461 aa)
ABCC5ATP binding cassette subfamily C member 5. (1437 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
SLC29A2Solute carrier family 29 member 2. (486 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
CALHM3Calcium homeostasis modulator 3. (344 aa)
SLC23A1Solute carrier family 23 member 1. (604 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
ABCC3ATP binding cassette subfamily C member 3. (1529 aa)
WASF2WASP family member 2. (493 aa)
A0A4W2FDM7TIR domain-containing protein. (1029 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
MUC20Uncharacterized protein. (704 aa)
SLC39A5Solute carrier family 39 member 5. (542 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
CTNNB1Catenin beta 1. (774 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (329 aa)
HEPHHephaestin; Belongs to the multicopper oxidase family. (1157 aa)
SPEF1Sperm flagellar 1. (236 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
SLC13A3Solute carrier family 13 member 3. (602 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
SLC43A3Solute carrier family 43 member 3. (489 aa)
NUMBNUMB endocytic adaptor protein. (642 aa)
SLC7A8Solute carrier family 7 member 8. (528 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
EZREzrin. (638 aa)
SLC38A1Solute carrier family 38 member 1. (486 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
SLC26A10Solute carrier family 26 member 10. (683 aa)
EPB41Erythrocyte membrane protein band 4.1. (956 aa)
A0A4W2CRW3Annexin. (346 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
LRP1LDL receptor related protein 1. (4544 aa)
A0A4W2CP79Annexin. (335 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
ABCC10ATP binding cassette subfamily C member 10. (1492 aa)
SLC16A8Solute carrier family 16 member 8. (500 aa)
C5AR2Complement component 5a receptor 2. (337 aa)
SLC29A1HATPase_c domain-containing protein. (574 aa)
ALPK2Alpha kinase 2. (2153 aa)
NDRG4NDRG family member 4. (402 aa)
A0A4W2CD19Ig-like domain-containing protein. (358 aa)
CDH16Cadherin 16. (829 aa)
SLC4A1Anion exchange protein. (1059 aa)
ABCC6ATP binding cassette subfamily C member 6. (1504 aa)
SLC26A6Solute carrier family 26 member 6. (763 aa)
MARVELD2MARVEL domain containing 2. (585 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
CDH17Cadherin 17. (832 aa)
ERBINErbb2 interacting protein. (1460 aa)
SLC16A3Solute carrier family 16 member 3. (461 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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