STRINGSTRING
SIX2 SIX2 CTNNB1 CTNNB1 FAT4 FAT4 WNT11 WNT11 OSR1 OSR1 DCHS1 DCHS1 KDR KDR SIX1 SIX1 BMP7 BMP7 TBX2 TBX2 PRRX1 PRRX1 BMP4 BMP4 SHH SHH WNT5A WNT5A FGF9 FGF9 WNT2 WNT2 SHOX2 SHOX2 BMP2 BMP2 MSX1 MSX1 FGF7 FGF7 PHF14 PHF14 FGF4 FGF4 DCHS2 DCHS2 HAND2 HAND2 SOX9 SOX9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIX2SIX homeobox 2. (296 aa)
CTNNB1Catenin beta 1. (774 aa)
FAT4FAT atypical cadherin 4. (4982 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
DCHS1Dachsous cadherin-related 1. (3525 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
SIX1SIX homeobox 1. (284 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
TBX2T-box transcription factor 2. (714 aa)
PRRX1Paired related homeobox 1. (245 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SHOX2Short stature homeobox 2. (331 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
MSX1Msh homeobox 1. (366 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PHF14PHD finger protein 14. (992 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
DCHS2Dachsous cadherin-related 2. (3360 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
SOX9SRY-box transcription factor 9. (524 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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