STRINGSTRING
TRIM65 TRIM65 LRRK2 LRRK2 TRIM32 TRIM32 SNX4 SNX4 WIPI1 WIPI1 HTT HTT LOC113905592 LOC113905592 LOC113905598 LOC113905598 BTNL9 BTNL9 SPTLC1 SPTLC1 DCN DCN SH3BP4 SH3BP4 KDR KDR ATG16L1 ATG16L1 ZC3H12A ZC3H12A TMEM59 TMEM59 PRKAA2 PRKAA2 PINK1 PINK1 RAB3GAP1 RAB3GAP1 ADRB2 ADRB2 A0A4W2DKI1 A0A4W2DKI1 SPTLC2 SPTLC2 HMOX1 HMOX1 RNF31 RNF31 ATG2A ATG2A DAPK1 DAPK1 A0A4W2DQK1 A0A4W2DQK1 SIRT1 SIRT1 A0A4W2DUJ6 A0A4W2DUJ6 ROCK1 ROCK1 HSPB8 HSPB8 PIP4K2B PIP4K2B SUPT5H SUPT5H GSK3A GSK3A ULK1 ULK1 TRIML1 TRIML1 NPRL2 NPRL2 KAT5 KAT5 FYCO1 FYCO1 SVIP SVIP FOXO1 FOXO1 TRIM13 TRIM13 CDK16 CDK16 TSC2 TSC2 TRIM38 TRIM38 WDR24 WDR24 TRIM6 TRIM6 NOD2 NOD2 PLK2 PLK2 A0A4W2EAH7 A0A4W2EAH7 RB1CC1 RB1CC1 BECN1 BECN1 LRSAM1 LRSAM1 AMBRA1 AMBRA1 A0A4W2EF22 A0A4W2EF22 IFNG IFNG CCNY CCNY MTDH MTDH C9orf72 C9orf72 SNX7 SNX7 GNAI3 GNAI3 IL4 IL4 TMEM173 TMEM173 FBXO7 FBXO7 LARP1 LARP1 TFEB TFEB PLK3 PLK3 FLCN FLCN RALB RALB PIP4K2C PIP4K2C TRIM8 TRIM8 SMCR8 SMCR8 ENDOG ENDOG ATG101 ATG101 RNF152 RNF152 PLEKHF1 PLEKHF1 PRKD1 PRKD1 SESN1 SESN1 HIF1A HIF1A PRKAA1 PRKAA1 VDAC1 VDAC1 DHRSX DHRSX TP53INP1 TP53INP1 SNX18 SNX18 ATF6 ATF6 MAPK3 MAPK3 NPRL3 NPRL3 TP53INP2 TP53INP2 STK11 STK11 WAC WAC RIPK2 RIPK2 FOXO3 FOXO3 UFL1 UFL1 TRIML2 TRIML2 TRIM21 TRIM21 PIP4K2A PIP4K2A TRIM68 TRIM68 ATG13 ATG13 TRIM27 TRIM27 RUFY4 RUFY4 NOD1 NOD1 A0A4W2CP57 A0A4W2CP57 VPS13D VPS13D SESN2 SESN2 EPM2A EPM2A RAB3GAP2 RAB3GAP2 TBK1 TBK1 PRKN PRKN SH3GLB1 SH3GLB1 PAFAH1B2 PAFAH1B2 TPCN1 TPCN1 DEPDC5 DEPDC5 BNIP3 BNIP3 BAG3 BAG3 CALCOCO2 CALCOCO2 SCOC SCOC ORMDL3 ORMDL3 A0A4W2BZD7 A0A4W2BZD7 A0A4W2BZ70 A0A4W2BZ70 SESN3 SESN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIM65Tripartite motif containing 65. (548 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
TRIM32Tripartite motif containing 32. (653 aa)
SNX4Sorting nexin 4. (454 aa)
WIPI1Uncharacterized protein. (572 aa)
HTTHuntingtin. (3119 aa)
LOC113905592Uncharacterized protein. (488 aa)
LOC113905598Uncharacterized protein. (511 aa)
BTNL9Butyrophilin like 9. (538 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (473 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ATG16L1Autophagy related 16 like 1. (623 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (583 aa)
TMEM59Uncharacterized protein. (334 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PINK1PTEN induced kinase 1. (588 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (991 aa)
ADRB2Adrenoceptor beta 2. (418 aa)
A0A4W2DKI1Uncharacterized protein. (92 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (617 aa)
HMOX1Heme oxygenase 1. (302 aa)
RNF31Uncharacterized protein. (1069 aa)
ATG2AAutophagy related 2A. (1928 aa)
DAPK1Death associated protein kinase 1. (1440 aa)
A0A4W2DQK1B30.2/SPRY domain-containing protein. (217 aa)
SIRT1Sirtuin 1. (734 aa)
A0A4W2DUJ6B30.2/SPRY domain-containing protein. (194 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1055 aa)
TRIML1Tripartite motif family like 1. (468 aa)
NPRL2NPR2 like, GATOR1 complex subunit. (433 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1454 aa)
SVIPUncharacterized protein. (77 aa)
FOXO1Forkhead box O1. (604 aa)
TRIM13Tripartite motif containing 13. (407 aa)
CDK16Cyclin dependent kinase 16. (571 aa)
TSC2TSC complex subunit 2. (1887 aa)
TRIM38Tripartite motif containing 38. (460 aa)
WDR24WD repeat domain 24. (790 aa)
TRIM6Tripartite motif containing 6. (613 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
PLK2Serine/threonine-protein kinase PLK. (864 aa)
A0A4W2EAH7Uncharacterized protein. (77 aa)
RB1CC1RB1 inducible coiled-coil 1. (1589 aa)
BECN1Beclin 1. (471 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (724 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1297 aa)
A0A4W2EF22Uncharacterized protein. (449 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
MTDHMetadherin. (613 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
SNX7Sorting nexin 7. (471 aa)
GNAI3G protein subunit alpha i3. (354 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (135 aa)
TMEM173Transmembrane protein 173. (484 aa)
FBXO7F-box protein 7. (522 aa)
LARP1La ribonucleoprotein domain family member 1. (1145 aa)
TFEBTranscription factor EB. (713 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
RALBRAS like proto-oncogene B. (206 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
TRIM8Tripartite motif containing 8. (551 aa)
SMCR8SMCR8-C9orf72 complex subunit. (938 aa)
ENDOGEndonuclease. (299 aa)
ATG101Autophagy related 101. (218 aa)
RNF152Ring finger protein 152. (204 aa)
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (279 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
SESN1Sestrin 1. (551 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
DHRSXDehydrogenase/reductase X-linked. (342 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (240 aa)
SNX18Sorting nexin. (626 aa)
ATF6Activating transcription factor 6. (733 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (224 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
WACWW domain containing adaptor with coiled-coil. (646 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
FOXO3Forkhead box O3. (617 aa)
UFL1UFM1 specific ligase 1. (792 aa)
TRIML2Tripartite motif family like 2. (434 aa)
TRIM21Tripartite motif containing 21. (511 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (405 aa)
TRIM68Tripartite motif containing 68. (485 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
TRIM27Tripartite motif containing 27. (513 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
A0A4W2CP57Uncharacterized protein. (285 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4369 aa)
SESN2Sestrin 2. (482 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1401 aa)
TBK1TANK binding kinase 1. (729 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (402 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (238 aa)
TPCN1Two pore segment channel 1. (916 aa)
DEPDC5DEP domain-containing protein. (1602 aa)
BNIP3BCL2 interacting protein 3. (196 aa)
BAG3BCL2 associated athanogene 3. (585 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (543 aa)
SCOCUncharacterized protein. (159 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
A0A4W2BZD7Uncharacterized protein. (136 aa)
A0A4W2BZ70B30.2/SPRY domain-containing protein. (208 aa)
SESN3Sestrin 3. (492 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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