STRINGSTRING
TGFB1 TGFB1 PRKCE PRKCE A0A4W2CEF6 A0A4W2CEF6 AQP1 AQP1 ITGB1 ITGB1 AKT1 AKT1 BAG4 BAG4 THBS1 THBS1 DDR2 DDR2 DMTN DMTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta 1. (443 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
BAG4BCL2 associated athanogene 4. (457 aa)
THBS1Thrombospondin 1. (1170 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (869 aa)
DMTNDematin actin binding protein. (467 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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