STRINGSTRING
PINK1 PINK1 BOK BOK KDR KDR DCN DCN SSBP1 SSBP1 BCL2L11 BCL2L11 HTT HTT ADCK1 ADCK1 GSK3B GSK3B PRKN PRKN HRK HRK DDHD1 DDHD1 MLLT11 MLLT11 CIDEB CIDEB BAX BAX BBC3 BBC3 MMP9 MMP9 ZDHHC6 ZDHHC6 PYCARD PYCARD TP53 TP53 VPS13D VPS13D PPARGC1A PPARGC1A FBXO7 FBXO7 PPIF PPIF TREM2 TREM2 FAM162A FAM162A MFF MFF BID BID MIEF1 MIEF1 PMAIP1 PMAIP1 HIP1R HIP1R DDHD2 DDHD2 BAD BAD BNIP3 BNIP3 MIEF2 MIEF2 A0A4W2C0N9 A0A4W2C0N9 MCU MCU SPIRE1 SPIRE1 PLD6 PLD6 VDAC1 VDAC1 ENDOG ENDOG ADCK5 ADCK5 STOML2 STOML2 PLAUR PLAUR TNFSF10 TNFSF10 MUL1 MUL1 VPS35 VPS35 HTRA2 HTRA2 AMBRA1 AMBRA1 RALA RALA A0A4W2E5D6 A0A4W2E5D6 ATP5IF1 ATP5IF1 HIF1A HIF1A GSK3A GSK3A A0A4W2E2B7 A0A4W2E2B7 GPER1 GPER1 RALBP1 RALBP1 DNM1L DNM1L ZNF205 ZNF205 AURKA AURKA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PINK1PTEN induced kinase 1. (588 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
SSBP1Single stranded DNA binding protein 1. (159 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa)
HTTHuntingtin. (3119 aa)
ADCK1AarF domain containing kinase 1. (523 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (432 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
HRKHarakiri, BCL2 interacting protein. (91 aa)
DDHD1DDHD domain containing 1. (944 aa)
MLLT11MLLT11 transcription factor 7 cofactor. (90 aa)
CIDEBCell death inducing DFFA like effector b. (219 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
BBC3Uncharacterized protein. (193 aa)
MMP9Matrix metallopeptidase 9. (712 aa)
ZDHHC6Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (413 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4369 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
FBXO7F-box protein 7. (522 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (208 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (244 aa)
FAM162AFamily with sequence similarity 162 member A. (156 aa)
MFFMitochondrial fission factor. (409 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
MIEF1Mitochondrial elongation factor 1. (463 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
HIP1RHuntingtin interacting protein 1 related. (1066 aa)
DDHD2DDHD domain containing 2. (708 aa)
BADBCL2 associated agonist of cell death. (168 aa)
BNIP3BCL2 interacting protein 3. (196 aa)
MIEF2Mitochondrial elongation factor 2. (454 aa)
A0A4W2C0N9AIF-MLS domain-containing protein. (357 aa)
MCUMitochondrial calcium uniporter. (355 aa)
SPIRE1Spire type actin nucleation factor 1. (781 aa)
PLD6Phospholipase D family member 6. (220 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
ENDOGEndonuclease. (299 aa)
ADCK5AarF domain containing kinase 5. (616 aa)
STOML2Stomatin like 2. (356 aa)
PLAURPlasminogen activator, urokinase receptor. (330 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (287 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (350 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1297 aa)
RALARAS like proto-oncogene A. (206 aa)
A0A4W2E5D6Uncharacterized protein. (144 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (109 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
A0A4W2E2B7Uncharacterized protein. (192 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
RALBP1RalA binding protein 1. (635 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
ZNF205Zinc finger protein 205. (550 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (402 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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