STRINGSTRING
SIX4 SIX4 CAPN2 CAPN2 A0A4W2CXB9 A0A4W2CXB9 WNT10B WNT10B DNER DNER DOCK2 DOCK2 SKI SKI NFATC2 NFATC2 RIPOR2 RIPOR2 CAV2 CAV2 CNTNAP1 CNTNAP1 A0A4W2CFT3 A0A4W2CFT3 CD9 CD9 DOCK1 DOCK1 MYMX MYMX BCL2 BCL2 PPP3CB PPP3CB MYOD1 MYOD1 ADAMTS15 ADAMTS15 CDON CDON DOCK5 DOCK5 MYOF MYOF CACNA1S CACNA1S A0A4W2E9C2 A0A4W2E9C2 DYRK1B DYRK1B PLEC PLEC R3HDM2 R3HDM2 P2RX2 P2RX2 NPHS1 NPHS1 A0A4W2EN60 A0A4W2EN60 ACTN1 ACTN1 KEL KEL SHH SHH PLEKHO1 PLEKHO1 BCL9 BCL9 TANC1 TANC1 MYH9 MYH9 PPP3CA PPP3CA KLF5 KLF5 SORT1 SORT1 PLD3 PLD3 ITGB1 ITGB1 ADGRB3 ADGRB3 KIF24-2 KIF24-2 SMO SMO KLHL40 KLHL40 BIN3 BIN3 ACTA1 ACTA1 CAV3 CAV3 BARX2 BARX2 HOMER1 HOMER1 STAC3 STAC3 WNT1 WNT1 IGF1 IGF1 CD81 CD81 ACTA2 ACTA2 SMYD3 SMYD3 MEF2C MEF2C A0A4W2DRC1 A0A4W2DRC1 GPX1 GPX1 MYMK MYMK LMOD3 LMOD3 SPG11 SPG11 TMEM182 TMEM182 ADAMTS5 ADAMTS5 KLHL41 KLHL41 SELENON SELENON SIX1 SIX1 PTGFRN PTGFRN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIX4SIX homeobox 4. (786 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
A0A4W2CXB9C2 domain-containing protein. (800 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (433 aa)
DNERDelta/notch like EGF repeat containing. (1010 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
SKISKI proto-oncogene. (736 aa)
NFATC2Nuclear factor of activated T cells 2. (914 aa)
RIPOR2PL48 domain-containing protein. (1065 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CNTNAP1Contactin associated protein 1. (1362 aa)
A0A4W2CFT3Uncharacterized protein. (336 aa)
CD9Tetraspanin. (266 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1888 aa)
MYMXMyomixer, myoblast fusion factor. (84 aa)
BCL2BCL2 apoptosis regulator. (229 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (318 aa)
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15. (939 aa)
CDONCell adhesion associated, oncogene regulated. (1247 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1864 aa)
MYOFMyoferlin. (2060 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
A0A4W2E9C2Uncharacterized protein. (461 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (719 aa)
PLECPlectin. (4671 aa)
R3HDM2Uncharacterized protein. (1023 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (535 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1242 aa)
A0A4W2EN60C2 domain-containing protein. (781 aa)
ACTN1Actinin alpha 1. (962 aa)
KELKell metallo-endopeptidase (Kell blood group). (721 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
PLEKHO1Pleckstrin homology domain containing O1. (409 aa)
BCL9BCL9 transcription coactivator. (1489 aa)
TANC1Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1. (1843 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
KLF5Kruppel like factor 5. (454 aa)
SORT1Sortilin. (909 aa)
PLD3Phospholipase D family member 3. (490 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
KIF24-2Myogenesis regulating glycosidase (putative); Belongs to the glycosyl hydrolase 31 family. (799 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
KLHL40Kelch like family member 40. (624 aa)
BIN3Bridging integrator 3. (253 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
BARX2BARX homeobox 2. (278 aa)
HOMER1Homer scaffold protein 1. (358 aa)
STAC3SH3 and cysteine rich domain 3. (362 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
IGF1Insulin like growth factor 1. (188 aa)
CD81Tetraspanin. (236 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
A0A4W2DRC1Uncharacterized protein. (166 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (204 aa)
MYMKMyomaker, myoblast fusion factor. (221 aa)
LMOD3Leiomodin 3. (567 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2428 aa)
TMEM182Transmembrane protein 182. (274 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (934 aa)
KLHL41Kelch like family member 41. (606 aa)
SELENONSelenoprotein N. (556 aa)
SIX1SIX homeobox 1. (284 aa)
PTGFRNProstaglandin F2 receptor inhibitor. (879 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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