STRINGSTRING
SERAC1 SERAC1 A0A4W2BND6 A0A4W2BND6 OSBPL5 OSBPL5 OSBPL10 OSBPL10 A0A4W2BUQ1 A0A4W2BUQ1 VAPA VAPA A0A4W2BV17 A0A4W2BV17 CEL CEL RELCH RELCH LIPG LIPG PNLIP PNLIP A0A4W2BXQ0 A0A4W2BXQ0 APOA5 APOA5 DRD2 DRD2 SLC18A2 SLC18A2 ARV1 ARV1 SLC18A1 SLC18A1 STARD5 STARD5 A0A4W2C5I5 A0A4W2C5I5 SELENOM SELENOM SLC29A4 SLC29A4 OSBP2 OSBP2 ABCC11 ABCC11 SLC16A3 SLC16A3 GRAMD1B GRAMD1B LCAT LCAT SLC26A6 SLC26A6 APOC3 APOC3 APOA4 APOA4 ATP8B1 ATP8B1 TPCN2 TPCN2 WNK4 WNK4 SLC5A12 SLC5A12 ABCA5 ABCA5 SLC10A7 SLC10A7 TSKU TSKU OSBP OSBP CFTR CFTR SLC16A8 SLC16A8 PIP4K2A PIP4K2A ABCA12 ABCA12 A0A4W2CLK8 A0A4W2CLK8 ABCG5 ABCG5 OSBPL3 OSBPL3 KANSL1L KANSL1L HNF1A HNF1A NPC1L1 NPC1L1 AQP9 AQP9 LIPC LIPC LOC113897218 LOC113897218 SLC10A2 SLC10A2 PRKN PRKN APOE APOE SLC22A2 SLC22A2 ABCD3 ABCD3 OSBPL11 OSBPL11 OSBPL8 OSBPL8 PLTP PLTP SLC10A1 SLC10A1 ASIC3 ASIC3 LRP6 LRP6 AQP7 AQP7 SLC2A13 SLC2A13 LDLRAP1 LDLRAP1 A0A4W2DFB5 A0A4W2DFB5 PINK1 PINK1 SLC22A3 SLC22A3 SPG11 SPG11 SLCO1A2 SLCO1A2 OSBPL9 OSBPL9 SLC6A4 SLC6A4 AQP11 AQP11 A0A4W2DMU2 A0A4W2DMU2 SLC5A8 SLC5A8 SYK SYK NPC1 NPC1 RALBP1 RALBP1 SLC10A6 SLC10A6 SLC51B SLC51B STAR STAR VPS4B VPS4B STARD3 STARD3 MSR1 MSR1 APOM APOM ABCA7 ABCA7 OSBPL7 OSBPL7 GRAMD1A GRAMD1A RBP4 RBP4 VPS4A VPS4A SLCO2B1 SLCO2B1 VIP VIP APOB APOB P2RX1 P2RX1 ARF6 ARF6 PARK7 PARK7 CHRM5 CHRM5 SLC22A1 SLC22A1 LIMA1 LIMA1 AQP2 AQP2 SOAT2 SOAT2 SLC51A SLC51A NPC2 NPC2 ABCA1 ABCA1 AQP3 AQP3 ABCB11 ABCB11 SLC10A4 SLC10A4 A0A4W2EY41 A0A4W2EY41 SCP2 SCP2 ABCG1 ABCG1 MTTP MTTP A0A4W2F271 A0A4W2F271 LDLR LDLR SOAT1 SOAT1 OSBPL6 OSBPL6 STRA6 STRA6 SLC16A7 SLC16A7 SCARB1 SCARB1 KCNQ1 KCNQ1 SLC6A3 SLC6A3 ABCG4 ABCG4 LOC113892546 LOC113892546 SLCO1C1 SLCO1C1 STARD4 STARD4 STX12 STX12 GRAMD1C GRAMD1C AQP1 AQP1 OSBPL1A OSBPL1A OSBPL2 OSBPL2 APOA2 APOA2 STARD3NL STARD3NL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERAC1Serine active site containing 1. (654 aa)
A0A4W2BND6IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
OSBPL5Oxysterol-binding protein; Belongs to the OSBP family. (872 aa)
OSBPL10Oxysterol-binding protein; Belongs to the OSBP family. (765 aa)
A0A4W2BUQ1ABC transporter domain-containing protein. (619 aa)
VAPAVAMP associated protein A. (294 aa)
A0A4W2BV17Uncharacterized protein. (963 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (599 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1220 aa)
LIPGLipase G, endothelial type. (512 aa)
PNLIPTriacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
A0A4W2BXQ0ABC transporter domain-containing protein. (623 aa)
APOA5Apolipoprotein A5. (368 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SLC18A2Solute carrier family 18 member A2. (682 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (282 aa)
SLC18A1Solute carrier family 18 member A1. (515 aa)
STARD5StAR related lipid transfer domain containing 5. (213 aa)
A0A4W2C5I5Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (104 aa)
SELENOMSelenoprotein M. (141 aa)
SLC29A4Solute carrier family 29 member 4. (523 aa)
OSBP2Oxysterol-binding protein; Belongs to the OSBP family. (916 aa)
ABCC11ATP binding cassette subfamily C member 11. (1379 aa)
SLC16A3Solute carrier family 16 member 3. (461 aa)
GRAMD1BGRAM domain containing 1B. (952 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
SLC26A6Solute carrier family 26 member 6. (763 aa)
APOC3Apolipoprotein C3. (99 aa)
APOA4Apolipoprotein A4. (380 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
TPCN2Uncharacterized protein. (752 aa)
WNK4WNK lysine deficient protein kinase 4. (1239 aa)
SLC5A12Solute carrier family 5 member 12; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (617 aa)
ABCA5ATP binding cassette subfamily A member 5. (1642 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (359 aa)
TSKUTsukushi, small leucine rich proteoglycan. (358 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (808 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
SLC16A8Solute carrier family 16 member 8. (500 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (405 aa)
ABCA12ATP binding cassette subfamily A member 12. (2596 aa)
A0A4W2CLK8ABC transporter domain-containing protein. (670 aa)
ABCG5ABC transporter domain-containing protein. (648 aa)
OSBPL3Oxysterol-binding protein; Belongs to the OSBP family. (887 aa)
KANSL1LKAT8 regulatory NSL complex subunit 1 like. (987 aa)
HNF1AHNF1 homeobox A. (633 aa)
NPC1L1NPC1 like intracellular cholesterol transporter 1. (1333 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
LIPCLipase C, hepatic type. (500 aa)
LOC113897218Uncharacterized protein. (618 aa)
SLC10A2Solute carrier family 10 member 2. (336 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
APOEApolipoprotein E. (349 aa)
SLC22A2Solute carrier family 22 member 2. (549 aa)
ABCD3ATP binding cassette subfamily D member 3. (659 aa)
OSBPL11Oxysterol-binding protein; Belongs to the OSBP family. (758 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (910 aa)
PLTPPhospholipid transfer protein. (496 aa)
SLC10A1Solute carrier family 10 member 1. (465 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (532 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1644 aa)
AQP7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (317 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (648 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (310 aa)
A0A4W2DFB5Oxysterol-binding protein; Belongs to the OSBP family. (421 aa)
PINK1PTEN induced kinase 1. (588 aa)
SLC22A3Solute carrier family 22 member 3. (625 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2428 aa)
SLCO1A2Solute carrier organic anion transporter family member. (666 aa)
OSBPL9Oxysterol-binding protein; Belongs to the OSBP family. (753 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
A0A4W2DMU2MENTAL domain-containing protein. (224 aa)
SLC5A8Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (611 aa)
SYKTyrosine-protein kinase. (628 aa)
NPC1NPC intracellular cholesterol transporter 1. (1291 aa)
RALBP1RalA binding protein 1. (635 aa)
SLC10A6Solute carrier family 10 member 6. (377 aa)
SLC51BSolute carrier family 51 beta subunit. (130 aa)
STARSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (350 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (530 aa)
STARD3StAR related lipid transfer domain containing 3. (472 aa)
MSR1Macrophage scavenger receptor 1. (454 aa)
APOMApolipoprotein M. (188 aa)
ABCA7ATP binding cassette subfamily A member 7. (2152 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (881 aa)
GRAMD1AGRAM domain containing 1A. (808 aa)
RBP4Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (314 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
SLCO2B1Solute carrier organic anion transporter family member. (799 aa)
VIPVasoactive intestinal peptide. (170 aa)
APOBApolipoprotein B. (4567 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
PARK7Parkinsonism associated deglycase. (190 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
SLC22A1Solute carrier family 22 member 1. (563 aa)
LIMA1LIM domain and actin binding 1. (761 aa)
AQP2Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SOAT2O-acyltransferase. (539 aa)
SLC51ASolute carrier family 51 alpha subunit. (340 aa)
NPC2NPC intracellular cholesterol transporter 2. (149 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
ABCB11ATP binding cassette subfamily B member 11. (1323 aa)
SLC10A4Solute carrier family 10 member 4. (448 aa)
A0A4W2EY41Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (418 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (543 aa)
ABCG1ATP binding cassette subfamily G member 1. (679 aa)
MTTPMicrosomal triglyceride transfer protein. (894 aa)
A0A4W2F271START domain-containing protein. (319 aa)
LDLRLow density lipoprotein receptor. (845 aa)
SOAT1O-acyltransferase. (575 aa)
OSBPL6Oxysterol-binding protein; Belongs to the OSBP family. (959 aa)
STRA6Stimulated by retinoic acid 6. (668 aa)
SLC16A7Solute carrier family 16 member 7. (482 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (586 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
LOC113892546Solute carrier organic anion transporter family member. (689 aa)
SLCO1C1Solute carrier organic anion transporter family member. (712 aa)
STARD4StAR related lipid transfer domain containing 4. (260 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (274 aa)
GRAMD1CGRAM domain containing 1C. (491 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (950 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (482 aa)
APOA2Apolipoprotein A2. (100 aa)
STARD3NLMENTAL domain-containing protein. (235 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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