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CIAO1 CIAO1 NFU1 NFU1 A0A4W2D6K0 A0A4W2D6K0 BOLA1 BOLA1 NFS1 NFS1 HSPA9 HSPA9 EME2 EME2 NARF NARF GLRX3 GLRX3 NUBPL NUBPL FXN FXN MMS19 MMS19 A0A4W2EGW5 A0A4W2EGW5 CIAO2A CIAO2A A0A4W2FHL7 A0A4W2FHL7 IBA57 IBA57 CIAPIN1 CIAPIN1 A0A4W2GVR0 A0A4W2GVR0 LYRM4 LYRM4 GLRX5 GLRX5 ISCA1 ISCA1 NUBP1 NUBP1 A0A4W2BNZ3 A0A4W2BNZ3 CIAO3 CIAO3 NDOR1 NDOR1 ISCU ISCU CIAO2B CIAO2B A0A4W2D252 A0A4W2D252
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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co-expression
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CIAO1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa)
NFU1NFU1 iron-sulfur cluster scaffold. (254 aa)
A0A4W2D6K0Uncharacterized protein; Belongs to the BolA/IbaG family. (200 aa)
BOLA1BolA family member 1; Belongs to the BolA/IbaG family. (138 aa)
NFS1Aminotran_5 domain-containing protein. (457 aa)
HSPA9Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
EME2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (445 aa)
NARFNuclear prelamin A recognition factor; Belongs to the NARF family. (469 aa)
GLRX3Glutaredoxin 3. (356 aa)
NUBPLNucleotide binding protein like. (385 aa)
FXNFrataxin. (236 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
A0A4W2EGW5NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (165 aa)
CIAO2ACytosolic iron-sulfur assembly component 2A. (160 aa)
A0A4W2FHL7NifU_N domain-containing protein. (136 aa)
IBA57Iron-sulfur cluster assembly factor IBA57. (358 aa)
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (310 aa)
A0A4W2GVR0Uncharacterized protein. (123 aa)
LYRM4Uncharacterized protein; Belongs to the complex I LYR family. (91 aa)
GLRX5Glutaredoxin 5. (158 aa)
ISCA1Iron-sulfur cluster assembly 1. (129 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (385 aa)
A0A4W2BNZ3Uncharacterized protein. (162 aa)
CIAO3Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. (476 aa)
NDOR1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (686 aa)
ISCUNifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)
CIAO2BCytosolic iron-sulfur assembly component 2B. (173 aa)
A0A4W2D252Fe-S_biosyn domain-containing protein. (320 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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