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CIAO1 | Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa) | ||||
NFU1 | NFU1 iron-sulfur cluster scaffold. (254 aa) | ||||
A0A4W2D6K0 | Uncharacterized protein; Belongs to the BolA/IbaG family. (200 aa) | ||||
BOLA1 | BolA family member 1; Belongs to the BolA/IbaG family. (138 aa) | ||||
NFS1 | Aminotran_5 domain-containing protein. (457 aa) | ||||
HSPA9 | Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa) | ||||
EME2 | Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (445 aa) | ||||
NARF | Nuclear prelamin A recognition factor; Belongs to the NARF family. (469 aa) | ||||
GLRX3 | Glutaredoxin 3. (356 aa) | ||||
NUBPL | Nucleotide binding protein like. (385 aa) | ||||
FXN | Frataxin. (236 aa) | ||||
MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa) | ||||
A0A4W2EGW5 | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (165 aa) | ||||
CIAO2A | Cytosolic iron-sulfur assembly component 2A. (160 aa) | ||||
A0A4W2FHL7 | NifU_N domain-containing protein. (136 aa) | ||||
IBA57 | Iron-sulfur cluster assembly factor IBA57. (358 aa) | ||||
CIAPIN1 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (310 aa) | ||||
A0A4W2GVR0 | Uncharacterized protein. (123 aa) | ||||
LYRM4 | Uncharacterized protein; Belongs to the complex I LYR family. (91 aa) | ||||
GLRX5 | Glutaredoxin 5. (158 aa) | ||||
ISCA1 | Iron-sulfur cluster assembly 1. (129 aa) | ||||
NUBP1 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (385 aa) | ||||
A0A4W2BNZ3 | Uncharacterized protein. (162 aa) | ||||
CIAO3 | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. (476 aa) | ||||
NDOR1 | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (686 aa) | ||||
ISCU | NifU_N domain-containing protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa) | ||||
CIAO2B | Cytosolic iron-sulfur assembly component 2B. (173 aa) | ||||
A0A4W2D252 | Fe-S_biosyn domain-containing protein. (320 aa) |