(85 nodes) N-acyltransferase activity network (Bos indicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CLUAP1	Clusterin associated protein 1. (561 aa)
	ALAS1	5'-aminolevulinate synthase 1. (752 aa)
	SMIM13	Small integral membrane protein 13. (90 aa)
	BRCA2	BRCA2 DNA repair associated. (3420 aa)
	KAT8	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
	A0A4W2BRQ1	LRAT domain-containing protein. (164 aa)
	A0A4W2BRQ8	LRAT domain-containing protein. (163 aa)
	PLAAT3	LRAT domain-containing protein. (162 aa)
	TLCD3B	TLC domain containing 3B. (275 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
	KAT6A	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2018 aa)
	EP300	E1A binding protein p300. (2411 aa)
	NAA60	N(alpha)-acetyltransferase 60, NatF catalytic subunit. (242 aa)
	C6orf136	Chromosome 6 open reading frame 136. (315 aa)
	AANAT	Aralkylamine N-acetyltransferase. (209 aa)
	CERS3	Ceramide synthase 3. (387 aa)
	A0A4W2C8V5	LRAT domain-containing protein. (188 aa)
	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit. (345 aa)
	LINS1	Lines homolog 1. (758 aa)
	TAF9	TATA-box binding protein associated factor 9. (264 aa)
	KAT7	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
	A0A4W2CIG1	Uncharacterized protein. (161 aa)
	NAT9	N-acetyltransferase 9 (putative). (211 aa)
	A0A4W2CLS5	Uncharacterized protein. (295 aa)
	GLYATL2	Uncharacterized protein. (299 aa)
	GTF2B	General transcription factor IIB. (316 aa)
	CERS5	Ceramide synthase 5. (452 aa)
	PLA2G4E	Phospholipase A2. (860 aa)
	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit. (169 aa)
	PLAAT1	LRAT domain-containing protein. (198 aa)
	A0A4W2D2I9	Uncharacterized protein. (377 aa)
	CERS4	Ceramide synthase 4. (393 aa)
	ACOT4	Acyl-CoA thioesterase 4. (575 aa)
	NCOA3	Nuclear receptor coactivator. (1411 aa)
	ATF2	Activating transcription factor 2. (447 aa)
	CLOCK	Clock circadian regulator. (844 aa)
	A0A4W2DDH8	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (523 aa)
	CREBBP	CREB binding protein. (2435 aa)
	MCM3AP	Minichromosome maintenance complex component 3 associated protein. (1979 aa)
	GTF3C4	General transcription factor IIIC subunit 4. (813 aa)
	CERS2	Ceramide synthase 2. (386 aa)
	SIRT1	Sirtuin 1. (734 aa)
	ALAS2	5-aminolevulinate synthase. (617 aa)
	SAT1	Spermidine/spermine N1-acetyltransferase 1. (171 aa)
	CERS6	Ceramide synthase 6. (392 aa)
	TAF1	Transcription initiation factor TFIID subunit. (1928 aa)
	KAT2A	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
	NAGS	N-acetylglutamate synthase. (534 aa)
	ATAT1	Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (409 aa)
	TLCD3A	TLC domain containing 3A. (258 aa)
	A0A4W2E748	Uncharacterized protein. (224 aa)
	ESCO1	Establishment of sister chromatid cohesion N-acetyltransferase 1. (843 aa)
	HGSNAT	Heparan-alpha-glucosaminide N-acetyltransferase. (657 aa)
	A0A4W2ED18	Uncharacterized protein. (251 aa)
	A0A4W2ED36	Uncharacterized protein. (295 aa)
	A0A4W2EFD0	Uncharacterized protein. (309 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
	SIRT7	Sirtuin 7. (420 aa)
	NMT2	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (498 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
	KAT14	Lysine acetyltransferase 14. (781 aa)
	TGM2	Transglutaminase 2. (687 aa)
	ESCO2	Establishment of sister chromatid cohesion N-acetyltransferase 2. (610 aa)
	C4orf48	Chromosome 4 open reading frame 48. (97 aa)
	CENPP	Centromere protein P. (345 aa)
	NAA35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit. (725 aa)
	NAA30	N(alpha)-acetyltransferase 30, NatC catalytic subunit. (359 aa)
	NAA11	N(alpha)-acetyltransferase 11, NatA catalytic subunit. (229 aa)
	METTL8	Methyltransf_25 domain-containing protein. (675 aa)
	KAT2B	Lysine acetyltransferase 2B. (990 aa)
	GNPNAT1	Glucosamine 6-phosphate N-acetyltransferase. (184 aa)
	A0A4W2FEW0	Uncharacterized protein. (109 aa)
	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit. (178 aa)
	USP22	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (480 aa)
	KAT6B	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1762 aa)
	NAT14	N-acetyltransferase 14 (putative). (206 aa)
	SAT2	Spermidine/spermine N1-acetyltransferase family member 2. (170 aa)
	NMT1	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
	NAT8L	N-acetyltransferase 8 like. (302 aa)
	NAA80	N(alpha)-acetyltransferase 80, NatH catalytic subunit. (309 aa)
	PLAAT5	Phospholipase A and acyltransferase 5. (271 aa)
	ELP3	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (547 aa)
	LOC113884909	Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family. (290 aa)
	GLYATL3	Glycine-N-acyltransferase like 3. (287 aa)
	SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (415 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2BRQ1	A0A4W2BRQ8	A0A4W2BRQ1	A0A4W2BRQ8	LRAT domain-containing protein.	LRAT domain-containing protein.	0.756
A0A4W2BRQ1	PLA2G4E	A0A4W2BRQ1	A0A4W2CYY6	LRAT domain-containing protein.	Phospholipase A2.	0.723
A0A4W2BRQ1	PLAAT3	A0A4W2BRQ1	A0A4W2BRR5	LRAT domain-containing protein.	LRAT domain-containing protein.	0.756
A0A4W2BRQ8	A0A4W2BRQ1	A0A4W2BRQ8	A0A4W2BRQ1	LRAT domain-containing protein.	LRAT domain-containing protein.	0.756
A0A4W2BRQ8	A0A4W2C8V5	A0A4W2BRQ8	A0A4W2C8V5	LRAT domain-containing protein.	LRAT domain-containing protein.	0.754
A0A4W2BRQ8	PLAAT3	A0A4W2BRQ8	A0A4W2BRR5	LRAT domain-containing protein.	LRAT domain-containing protein.	0.807
A0A4W2C8V5	A0A4W2BRQ8	A0A4W2C8V5	A0A4W2BRQ8	LRAT domain-containing protein.	LRAT domain-containing protein.	0.754
A0A4W2C8V5	PLA2G4E	A0A4W2C8V5	A0A4W2CYY6	LRAT domain-containing protein.	Phospholipase A2.	0.723
A0A4W2C8V5	PLAAT3	A0A4W2C8V5	A0A4W2BRR5	LRAT domain-containing protein.	LRAT domain-containing protein.	0.753
A0A4W2CIG1	A0A4W2ED36	A0A4W2CIG1	A0A4W2ED36	Uncharacterized protein.	Uncharacterized protein.	0.547
A0A4W2CLS5	A0A4W2ED36	A0A4W2CLS5	A0A4W2ED36	Uncharacterized protein.	Uncharacterized protein.	0.812
A0A4W2D2I9	A0A4W2ED36	A0A4W2D2I9	A0A4W2ED36	Uncharacterized protein.	Uncharacterized protein.	0.812
A0A4W2DDH8	ATF2	A0A4W2DDH8	A0A4W2D7L6	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Activating transcription factor 2.	0.511
A0A4W2DDH8	KAT2A	A0A4W2DDH8	A0A4W2E363	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.476
A0A4W2DDH8	KAT2B	A0A4W2DDH8	A0A4W2F492	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Lysine acetyltransferase 2B.	0.476
A0A4W2ED18	A0A4W2ED36	A0A4W2ED18	A0A4W2ED36	Uncharacterized protein.	Uncharacterized protein.	0.545
A0A4W2ED36	A0A4W2CIG1	A0A4W2ED36	A0A4W2CIG1	Uncharacterized protein.	Uncharacterized protein.	0.547
A0A4W2ED36	A0A4W2CLS5	A0A4W2ED36	A0A4W2CLS5	Uncharacterized protein.	Uncharacterized protein.	0.812
A0A4W2ED36	A0A4W2D2I9	A0A4W2ED36	A0A4W2D2I9	Uncharacterized protein.	Uncharacterized protein.	0.812
A0A4W2ED36	A0A4W2ED18	A0A4W2ED36	A0A4W2ED18	Uncharacterized protein.	Uncharacterized protein.	0.545

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