(31 nodes) Chemokine binding network (Bos indicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1338 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
	CXCR4	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	ACKR4	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	A0A4W2DET3	Uncharacterized protein. (527 aa)
	CCR8	C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	CCR5	C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
	CXCR3	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (409 aa)
	XCR1	X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
	A0A4W2DXG8	G_PROTEIN_RECEP_F1_2 domain-containing protein. (385 aa)
	PDPN	Uncharacterized protein. (169 aa)
	CCR9	C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (367 aa)
	CCR1	C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	A0A4W2EF50	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	CXCR2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	A0A4W2CEF6	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	ZFP36	ZFP36 ring finger protein. (325 aa)
	PLP2	MARVEL domain-containing protein. (150 aa)
	CCR2	C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	CCRL2	C-C motif chemokine receptor like 2; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	CXCR6	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (340 aa)
	CCR4	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (411 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	CXCR5	C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	CCR3	C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	CX3CR1	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	CCR10	C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (365 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2CEF6	ITGA4	A0A4W2CEF6	A0A4W2D5X0	Integrin beta; Belongs to the integrin beta chain family.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.929
A0A4W2CEF6	ITGAV	A0A4W2CEF6	A0A4W2FBC2	Integrin beta; Belongs to the integrin beta chain family.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.999
A0A4W2CEF6	ITGB1	A0A4W2CEF6	A0A4W2GGZ1	Integrin beta; Belongs to the integrin beta chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.827
A0A4W2DET3	ACKR3	A0A4W2DET3	A0A4W2EVC4	Uncharacterized protein.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.626
A0A4W2DET3	ACKR4	A0A4W2DET3	A0A4W2F192	Uncharacterized protein.	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.722
A0A4W2DET3	CCR2	A0A4W2DET3	A0A4W2BW75	Uncharacterized protein.	C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.458
A0A4W2DET3	CCR5	A0A4W2DET3	A0A4W2DPS5	Uncharacterized protein.	C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family.	0.440
A0A4W2EF50	ACKR3	A0A4W2EF50	A0A4W2EVC4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.415
A0A4W2EF50	CCR1	A0A4W2EF50	A0A4W2E9S2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.651
A0A4W2EF50	CCR10	A0A4W2EF50	A0A4W2IKY4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family.	0.418
A0A4W2EF50	CCR2	A0A4W2EF50	A0A4W2BW75	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.684
A0A4W2EF50	CCR3	A0A4W2EF50	A0A4W2I867	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.535
A0A4W2EF50	CCR4	A0A4W2EF50	A0A4W2BSB1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.471
A0A4W2EF50	CCR5	A0A4W2EF50	A0A4W2DPS5	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family.	0.816
A0A4W2EF50	CCR7	A0A4W2EF50	A0A4W2CEK0	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.562
A0A4W2EF50	CCR8	A0A4W2EF50	A0A4W2DNB8	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family.	0.479
A0A4W2EF50	CCR9	A0A4W2EF50	A0A4W2E9R2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family.	0.513
A0A4W2EF50	CXCR2	A0A4W2EF50	A0A4W2CM48	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.856
A0A4W2EF50	CXCR3	A0A4W2EF50	A0A4W2DTP2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.634
A0A4W2EF50	CXCR4	A0A4W2EF50	A0A4W2F1R8	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.923

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