STRINGSTRING
WASF3 WASF3 CDC42 CDC42 DPYSL3 DPYSL3 PKD2 PKD2 HAX1 HAX1 WASL WASL A0A4W2DA03 A0A4W2DA03 ARHGEF7 ARHGEF7 CDK5 CDK5 SNX2 SNX2 SPEF1 SPEF1 PALLD PALLD CAPRIN1 CAPRIN1 IQGAP2 IQGAP2 AJUBA AJUBA SYNE2 SYNE2 ARHGAP31 ARHGAP31 RAPGEF3 RAPGEF3 FER FER MYLK MYLK PHACTR4 PHACTR4 SNX1 SNX1 CDH1 CDH1 SCYL3 SCYL3 FSCN3 FSCN3 CD44 CD44 MYO1G MYO1G EVL EVL PABPC1 PABPC1 KPTN KPTN ALS2 ALS2 PLCE1 PLCE1 ILK ILK STX3 STX3 CCDC88A CCDC88A CAPG CAPG A0A4W2CEF6 A0A4W2CEF6 P4HB P4HB RAC1 RAC1 APC APC RAC3 RAC3 ARPIN ARPIN PDXP PDXP MYH10 MYH10 CARMIL1 CARMIL1 LOC113884473 LOC113884473 SPATA13 SPATA13 PARVB PARVB FAT1 FAT1 DBNL DBNL DAG1 DAG1 BCAR1 BCAR1 CDH2 CDH2 CORO1A CORO1A PLXND1 PLXND1 PTPRM PTPRM SLC39A6 SLC39A6 CTNNB1 CTNNB1 ACTR3 ACTR3 CORO1B CORO1B TSC1 TSC1 A0A4W2DSF5 A0A4W2DSF5 A0A4W2DVQ4 A0A4W2DVQ4 ROCK1 ROCK1 AIF1 AIF1 ACTB ACTB UNC5C UNC5C IGF2BP1 IGF2BP1 SH3BP1 SH3BP1 ABI2 ABI2 FLOT2 FLOT2 CORO1C CORO1C APBB1 APBB1 PDPN PDPN CARMIL2 CARMIL2 TESK1 TESK1 INPPL1 INPPL1 ABI1 ABI1 ITGB1BP1 ITGB1BP1 A0A4W2EE88 A0A4W2EE88 ARPC3 ARPC3 CDC42BPA CDC42BPA PLCG1 PLCG1 ANTXR1 ANTXR1 PDLIM4 PDLIM4 ACTN1 ACTN1 PTK2B PTK2B PIP5K1A PIP5K1A APC2 APC2 DPP4 DPP4 CLRN1 CLRN1 EPHA2 EPHA2 RAC2 RAC2 A0A4W2F1L2 A0A4W2F1L2 CYFIP1 CYFIP1 SH3RF1 SH3RF1 MYO10 MYO10 ITGAV ITGAV WASF1 WASF1 WASF2 WASF2 KITLG KITLG RHOA RHOA ABITRAM ABITRAM CTNNA1 CTNNA1 PARVA PARVA FSCN1 FSCN1 STMN2 STMN2 ITGB1 ITGB1 VASP VASP FAP FAP ACTA1 ACTA1 ARPC5 ARPC5 CARMIL3 CARMIL3 BRK1 BRK1 PKN2 PKN2 PPP1R9B PPP1R9B RAB13 RAB13 ABI3 ABI3 A0A4W2HDV8 A0A4W2HDV8 NF2 NF2 TWF2 TWF2 TUBB3 TUBB3 CFL1 CFL1 FLOT1 FLOT1 STX2 STX2 ACTC1 ACTC1 CIB3 CIB3 PAK1 PAK1 CIB1 CIB1 DGKZ DGKZ SHTN1 SHTN1 PLEKHH2 PLEKHH2 CTTN CTTN ACTA2 ACTA2 VIL1 VIL1 GDPD2 GDPD2 LIMK1 LIMK1 PIK3CA PIK3CA KCNA2 KCNA2 CORO6 CORO6 ABLIM3 ABLIM3 A0A4W2DJN4 A0A4W2DJN4 GSN GSN CAPZB CAPZB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WASF3WASP family member 3. (501 aa)
CDC42Cell division cycle 42. (191 aa)
DPYSL3Dihydropyrimidinase like 3. (684 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
HAX1HCLS1 associated protein X-1. (287 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
A0A4W2DA03Uncharacterized protein; Belongs to the actin family. (416 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SNX2Sorting nexin 2. (536 aa)
SPEF1Sperm flagellar 1. (236 aa)
PALLDPalladin, cytoskeletal associated protein. (1355 aa)
CAPRIN1Cell cycle associated protein 1. (708 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1575 aa)
AJUBAAjuba LIM protein. (564 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6919 aa)
ARHGAP31Rho GTPase activating protein 31. (1451 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
MYLKMyosin light chain kinase. (2163 aa)
PHACTR4Phosphatase and actin regulator. (712 aa)
SNX1Sorting nexin 1. (522 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (883 aa)
SCYL3SCY1 like pseudokinase 3. (734 aa)
FSCN3Fascin. (497 aa)
CD44CD44 molecule (Indian blood group). (850 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (995 aa)
EVLEnah/Vasp-like. (455 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
KPTNKaptin, actin binding protein. (436 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1656 aa)
PLCE1Phosphoinositide phospholipase C. (1572 aa)
ILKIntegrin linked kinase. (452 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (359 aa)
CCDC88ACoiled-coil domain containing 88A. (1842 aa)
CAPGCapping actin protein, gelsolin like. (412 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
P4HBProtein disulfide-isomerase. (565 aa)
RAC1Rac family small GTPase 1. (257 aa)
APCAPC regulator of WNT signaling pathway. (2912 aa)
RAC3Rac family small GTPase 3. (258 aa)
ARPINUncharacterized protein. (226 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1426 aa)
LOC113884473CH_2 domain-containing protein. (271 aa)
SPATA13Uncharacterized protein. (1260 aa)
PARVBParvin beta. (365 aa)
FAT1FAT atypical cadherin 1. (4587 aa)
DBNLDrebrin like. (503 aa)
DAG1Dystroglycan 1. (1096 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (919 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (1318 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
PLXND1Plexin D1. (1930 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1497 aa)
SLC39A6Solute carrier family 39 member 6. (747 aa)
CTNNB1Catenin beta 1. (774 aa)
ACTR3Uncharacterized protein; Belongs to the actin family. (418 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (488 aa)
TSC1TSC complex subunit 1. (1165 aa)
A0A4W2DSF5Uncharacterized protein. (101 aa)
A0A4W2DVQ4Death domain-containing protein. (237 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
ACTBActin beta. (375 aa)
UNC5CUnc-5 netrin receptor C. (930 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
SH3BP1Uncharacterized protein. (693 aa)
ABI2Abl interactor 2. (542 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (493 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (828 aa)
PDPNUncharacterized protein. (169 aa)
CARMIL2Uncharacterized protein. (1372 aa)
TESK1Testis associated actin remodelling kinase 1. (630 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
ABI1Abl interactor 1. (508 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
A0A4W2EE88Uncharacterized protein. (509 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (190 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1810 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
ANTXR1ANTXR cell adhesion molecule 1. (564 aa)
PDLIM4PDZ and LIM domain 4. (311 aa)
ACTN1Actinin alpha 1. (962 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
APC2APC regulator of WNT signaling pathway 2. (2264 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (747 aa)
CLRN1Clarin 1. (232 aa)
EPHA2EPH receptor A2. (1007 aa)
RAC2Rac family small GTPase 2. (209 aa)
A0A4W2F1L2Uncharacterized protein. (186 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SH3RF1SH3 domain containing ring finger 1. (828 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
WASF1WASP family member 1. (570 aa)
WASF2WASP family member 2. (493 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (249 aa)
RHOARas homolog family member A. (193 aa)
ABITRAMActin binding transcription modulator. (187 aa)
CTNNA1Catenin alpha 1. (919 aa)
PARVAParvin alpha. (455 aa)
FSCN1Fascin. (493 aa)
STMN2Stathmin; Belongs to the stathmin family. (179 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
CARMIL3Capping protein regulator and myosin 1 linker 3. (1372 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
PKN2Protein kinase N2. (981 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (817 aa)
RAB13Uncharacterized protein. (203 aa)
ABI3ABI family member 3. (359 aa)
A0A4W2HDV8Uncharacterized protein. (442 aa)
NF2Neurofibromin 2. (596 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (512 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (317 aa)
ACTC1Actin alpha cardiac muscle 1. (377 aa)
CIB3Calcium and integrin binding family member 3. (187 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
CIB1Calcium and integrin binding 1. (191 aa)
DGKZDiacylglycerol kinase. (1193 aa)
SHTN1Shootin 1. (628 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1491 aa)
CTTNCortactin. (538 aa)
ACTA2Actin alpha 2, smooth muscle. (377 aa)
VIL1Villin 1. (827 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (539 aa)
LIMK1LIM domain kinase 1. (778 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (471 aa)
ABLIM3Actin binding LIM protein family member 3. (683 aa)
A0A4W2DJN4Uncharacterized protein; Belongs to the actin family. (356 aa)
GSNGelsolin. (846 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (306 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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