STRINGSTRING
RIN2 RIN2 AMN AMN DNM2 DNM2 APPL1 APPL1 RABGEF1 RABGEF1 RAB11FIP3 RAB11FIP3 RAB7A RAB7A CORO1A CORO1A RIN1 RIN1 A0A4W2BV17 A0A4W2BV17 EHD1 EHD1 HYAL2 HYAL2 A0A4W2BXG6 A0A4W2BXG6 ADAM8 ADAM8 EPN2 EPN2 LOC113882062 LOC113882062 A0A4W2C2X4 A0A4W2C2X4 FFAR4 FFAR4 MYO1C MYO1C TLR2 TLR2 STX8 STX8 PLD4 PLD4 VPS9D1 VPS9D1 CEMIP CEMIP LMBRD1 LMBRD1 HEATR5A HEATR5A CLEC4E CLEC4E TCIRG1 TCIRG1 MYO6 MYO6 RAB11FIP1 RAB11FIP1 PIP4P2 PIP4P2 PIK3C2B PIK3C2B AP2S1 AP2S1 VIM VIM A0A4W2CK57 A0A4W2CK57 RAB36 RAB36 NOD1 NOD1 SLC11A1 SLC11A1 ZDHHC5 ZDHHC5 CTLA4 CTLA4 STX7 STX7 A0A4W2ILH9 A0A4W2ILH9 RAB14 RAB14 HEATR5B HEATR5B EHD2 EHD2 CPNE6 CPNE6 RAB8B RAB8B RAB39A RAB39A RINL RINL RAB38 RAB38 SRGAP2 SRGAP2 LPAR2 LPAR2 STX12 STX12 RAB9A RAB9A RAB13 RAB13 EHD3 EHD3 ANXA11 ANXA11 STX6 STX6 ADGB-2 ADGB-2 RAB22A RAB22A SLAMF1 SLAMF1 RAB8A RAB8A STXBP1 STXBP1 RAB5B RAB5B STXBP3 STXBP3 A0A4W2FPD6 A0A4W2FPD6 RAPGEF2 RAPGEF2 RAB7B RAB7B A0A4W2FDM7 A0A4W2FDM7 SNX3 SNX3 RAB5A RAB5A SGIP1 SGIP1 STAM2 STAM2 TLR6 TLR6 DPP4 DPP4 RAB17 RAB17 ATG14 ATG14 CLCN3 CLCN3 PLD1 PLD1 RAB11A RAB11A AP2M1 AP2M1 ABCA1 ABCA1 LPAR1 LPAR1 RAB11FIP5 RAB11FIP5 ARF6 ARF6 LAMP1 LAMP1 AP2A1 AP2A1 VPS26B VPS26B AMBRA1 AMBRA1 DAB2IP DAB2IP BECN1 BECN1 RALA RALA NOD2 NOD2 ARRB2 ARRB2 PIK3C3 PIK3C3 KIF5B KIF5B CDC42EP4 CDC42EP4 RABEP1 RABEP1 A0A4W2E5Z3 A0A4W2E5Z3 FLOT2 FLOT2 A0A4W2E497 A0A4W2E497 INPP5F INPP5F RIN3 RIN3 RAB35 RAB35 SPHK1 SPHK1 A0A4W2DWP1 A0A4W2DWP1 A0A4W2DVS8 A0A4W2DVS8 A0A4W2DUT8 A0A4W2DUT8 LRP2 LRP2 AP2A2 AP2A2 RAB11FIP4 RAB11FIP4 SCARB2 SCARB2 RAB23 RAB23 ANXA3 ANXA3 RAB34 RAB34 A0A4W2DRG4 A0A4W2DRG4 A0A4W2DQ54 A0A4W2DQ54 RAB31 RAB31 CLTC CLTC RAB43 RAB43 WAS WAS SYK SYK APPL2 APPL2 SYT11 SYT11 GSN GSN CDC42 CDC42 TYRP1 TYRP1 A0A4W2DEN7 A0A4W2DEN7 INPP5B INPP5B ZYX ZYX SLC18A3 SLC18A3 EHD4 EHD4 RAB11B RAB11B IGF2R IGF2R GAPVD1 GAPVD1 AVPR1A AVPR1A OCLN OCLN MTOR MTOR PLEKHG5 PLEKHG5 MYO1E MYO1E TRIM14 TRIM14 RAB20 RAB20 DYSF DYSF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIN2Ras and Rab interactor 2. (909 aa)
AMNAmnion associated transmembrane protein. (508 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
RABGEF1Uncharacterized protein. (783 aa)
RAB11FIP3RAB11 family interacting protein 3. (741 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
RIN1Ras and Rab interactor 1. (790 aa)
A0A4W2BV17Uncharacterized protein. (963 aa)
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (548 aa)
HYAL2Hyaluronidase. (473 aa)
A0A4W2BXG6MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (341 aa)
ADAM8ADAM metallopeptidase domain 8. (772 aa)
EPN2Epsin 2. (644 aa)
LOC113882062Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa)
A0A4W2C2X4Ig-like domain-containing protein; Belongs to the MHC class I family. (356 aa)
FFAR4Free fatty acid receptor 4. (361 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (861 aa)
STX8Syntaxin 8. (369 aa)
PLD4Phospholipase D family member 4. (539 aa)
VPS9D1VPS9 domain containing 1. (737 aa)
CEMIPCell migration inducing hyaluronidase 1. (1416 aa)
LMBRD1LMBR1 domain containing 1. (543 aa)
HEATR5AHEAT repeat containing 5A. (2054 aa)
CLEC4EC-type lectin domain family 4 member E. (211 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
RAB11FIP1Uncharacterized protein. (712 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (275 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
AP2S1Adaptor related protein complex 2 subunit sigma 1. (231 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
A0A4W2CK57Ig-like domain-containing protein; Belongs to the MHC class I family. (375 aa)
RAB36RAB36, member RAS oncogene family. (314 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
SLC11A1Solute carrier family 11 member 1. (601 aa)
ZDHHC5Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (714 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (221 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
A0A4W2ILH9Uncharacterized protein. (72 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
HEATR5BHEAT repeat containing 5B. (2070 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
CPNE6Copine 6. (557 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
RINLRas and Rab interactor like. (562 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
SRGAP2Uncharacterized protein. (1084 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (274 aa)
RAB9ARAB9A, member RAS oncogene family. (203 aa)
RAB13Uncharacterized protein. (203 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (528 aa)
ANXA11Annexin. (503 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
ADGB-2RAB32, member RAS oncogene family. (225 aa)
RAB22ARAB22A, member RAS oncogene family. (194 aa)
SLAMF1Ig-like domain-containing protein. (338 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
RAB5BRAB5B, member RAS oncogene family. (215 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (576 aa)
A0A4W2FPD6Uncharacterized protein. (53 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1689 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
A0A4W2FDM7TIR domain-containing protein. (1029 aa)
SNX3Sorting nexin 3. (162 aa)
RAB5AUncharacterized protein. (215 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (825 aa)
STAM2Signal transducing adaptor molecule 2. (526 aa)
TLR6Toll-like receptor. (796 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (747 aa)
RAB17RAB17, member RAS oncogene family. (233 aa)
ATG14Autophagy related 14. (550 aa)
CLCN3Chloride channel protein. (872 aa)
PLD1Phospholipase. (1126 aa)
RAB11ARAB11A, member RAS oncogene family. (236 aa)
AP2M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (435 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
RAB11FIP5Uncharacterized protein. (1317 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
LAMP1Lysosomal associated membrane protein 1. (409 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
VPS26BVPS26, retromer complex component B. (384 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1297 aa)
DAB2IPDAB2 interacting protein. (1267 aa)
BECN1Beclin 1. (471 aa)
RALARAS like proto-oncogene A. (206 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
ARRB2Arrestin beta 2. (409 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (990 aa)
CDC42EP4CDC42 effector protein 4. (351 aa)
RABEP1Rabaptin, RAB GTPase binding effector protein 1. (902 aa)
A0A4W2E5Z3Uncharacterized protein. (338 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
A0A4W2E497MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (243 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
RIN3Ras and Rab interactor 3. (1011 aa)
RAB35RAB35, member RAS oncogene family. (263 aa)
SPHK1Sphingosine kinase 1. (489 aa)
A0A4W2DWP1MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (231 aa)
A0A4W2DVS8Ig-like domain-containing protein. (529 aa)
A0A4W2DUT8TIR domain-containing protein. (408 aa)
LRP2LDL receptor related protein 2. (4647 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (935 aa)
RAB11FIP4RAB11 family interacting protein 4. (637 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (520 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
ANXA3Annexin. (323 aa)
RAB34RAB34, member RAS oncogene family. (360 aa)
A0A4W2DRG4PDZ domain-containing protein. (303 aa)
A0A4W2DQ54Uncharacterized protein. (560 aa)
RAB31RAB31, member RAS oncogene family. (224 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
RAB43Uncharacterized protein. (302 aa)
WASWASP actin nucleation promoting factor. (559 aa)
SYKTyrosine-protein kinase. (628 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (659 aa)
SYT11Synaptotagmin 11. (461 aa)
GSNGelsolin. (846 aa)
CDC42Cell division cycle 42. (191 aa)
TYRP1Tyrosinase related protein 1. (596 aa)
A0A4W2DEN7Uncharacterized protein. (913 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (924 aa)
ZYXZyxin. (612 aa)
SLC18A3Solute carrier family 18 member A3. (524 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (540 aa)
RAB11BUncharacterized protein. (267 aa)
IGF2RInsulin like growth factor 2 receptor. (2454 aa)
GAPVD1GTPase activating protein and VPS9 domains 1. (1461 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1143 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
TRIM14Tripartite motif containing 14. (504 aa)
RAB20RAB20, member RAS oncogene family. (231 aa)
DYSFDysferlin. (2121 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.