STRINGSTRING
SHISA6 SHISA6 SRR SRR SLC22A12 SLC22A12 PLEKHA2 PLEKHA2 CADM1 CADM1 KCNJ4 KCNJ4 PLEKHA1 PLEKHA1 KIF14 KIF14 SLC9A3R1 SLC9A3R1 SLC26A6 SLC26A6 FZD7 FZD7 NKPD1 NKPD1 CFTR CFTR SDC2 SDC2 LZTS3 LZTS3 ARHGEF16 ARHGEF16 NKD1 NKD1 PRKN PRKN CRIPT CRIPT PDZK1 PDZK1 ATP2B1 ATP2B1 GPR37 GPR37 CXADR CXADR SNTG2 SNTG2 SLC22A5 SLC22A5 A0A4W2DUV7 A0A4W2DUV7 LLGL2 LLGL2 SHISA9 SHISA9 ADRB1 ADRB1 TBC1D10A TBC1D10A ADGRB1 ADGRB1 LNX2 LNX2 KIDINS220 KIDINS220 ADAM17 ADAM17 FZD4 FZD4 GJA1 GJA1 GNG5 GNG5 FZD2 FZD2 FZD8 FZD8 C16orf70 C16orf70 PRKCA PRKCA TMEM88 TMEM88 F11R F11R GRASP GRASP TMEM88B TMEM88B MAP2K2 MAP2K2 RAPGEF2 RAPGEF2 FZD1 FZD1 IGSF5 IGSF5 GRID2 GRID2 USHBP1 USHBP1 LNX1 LNX1 CLCN3 CLCN3 PSEN1 PSEN1 LPAR1 LPAR1 ARHGAP29 ARHGAP29 FZD3 FZD3 CRIM1 CRIM1 CIT CIT ACOX1 ACOX1 EXOC4 EXOC4 DOCK4 DOCK4 SSTR2 SSTR2 NSF NSF ATP2B2 ATP2B2 MPP3 MPP3 ATP2B4 ATP2B4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHISA6Shisa family member 6. (552 aa)
SRRSerine racemase. (373 aa)
SLC22A12Solute carrier family 22 member 12. (524 aa)
PLEKHA2Pleckstrin homology domain containing A2. (425 aa)
CADM1Cell adhesion molecule 1. (478 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (444 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1624 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (368 aa)
SLC26A6Solute carrier family 26 member 6. (763 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
NKPD1NTPase KAP family P-loop domain containing 1. (828 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
LZTS3Leucine zipper tumor suppressor family member 3. (672 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (708 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (471 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
CRIPTCXXC repeat containing interactor of PDZ3 domain. (101 aa)
PDZK1PDZ domain containing 1. (732 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
GPR37G protein-coupled receptor 37. (613 aa)
CXADRUncharacterized protein. (403 aa)
SNTG2Syntrophin gamma 2. (544 aa)
SLC22A5Solute carrier family 22 member 5. (557 aa)
A0A4W2DUV7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (87 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1022 aa)
SHISA9Shisa family member 9. (425 aa)
ADRB1Adrenoceptor beta 1. (514 aa)
TBC1D10ATBC1 domain family member 10A. (506 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1457 aa)
LNX2Ligand of numb-protein X 2. (682 aa)
KIDINS220Kinase D interacting substrate 220. (1781 aa)
ADAM17ADAM metallopeptidase domain 17. (825 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (383 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (661 aa)
C16orf70Chromosome 16 open reading frame 70. (422 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
TMEM88Transmembrane protein 88. (159 aa)
F11RF11 receptor. (298 aa)
GRASPGeneral receptor for phosphoinositides 1 associated scaffold protein. (394 aa)
TMEM88BTransmembrane protein 88B. (159 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (447 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1689 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (645 aa)
IGSF5Ig-like domain-containing protein. (370 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
USHBP1USH1 protein network component harmonin binding protein 1. (698 aa)
LNX1Ligand of numb-protein X 1. (787 aa)
CLCN3Chloride channel protein. (872 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
ARHGAP29Rho GTPase activating protein 29. (1269 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1035 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (676 aa)
EXOC4Exocyst complex component 4. (976 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1973 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (368 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (797 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
MPP3Membrane palmitoylated protein 3; Belongs to the MAGUK family. (585 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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