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TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa) | ||||
BRCA2 | BRCA2 DNA repair associated. (3420 aa) | ||||
PIDD1 | P53-induced death domain protein 1. (946 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) | ||||
A0A4W2BZA0 | Fork-head domain-containing protein. (697 aa) | ||||
A0A4W2C0C3 | 40S ribosomal protein S27. (95 aa) | ||||
A0A4W2C3D5 | Uncharacterized protein. (223 aa) | ||||
MYO6 | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa) | ||||
FOXO3 | Forkhead box O3. (617 aa) | ||||
BCL3 | BCL3 transcription coactivator. (454 aa) | ||||
USP10 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (800 aa) | ||||
ING4 | Inhibitor of growth protein. (248 aa) | ||||
SESN2 | Sestrin 2. (482 aa) | ||||
ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (319 aa) | ||||
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain. (287 aa) | ||||
CASP2 | Caspase 2; Belongs to the peptidase C14A family. (452 aa) | ||||
PAXIP1 | PAX interacting protein 1. (983 aa) | ||||
PPM1D | Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa) | ||||
A0A4W2DWY9 | UPAR/Ly6 domain-containing protein. (155 aa) | ||||
CHEK2 | Checkpoint kinase 2. (534 aa) | ||||
NDRG1 | N-myc downstream regulated 1. (415 aa) | ||||
PML | Promyelocytic leukemia. (871 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (161 aa) | ||||
FOXM1 | Fork-head domain-containing protein. (760 aa) | ||||
RPS27L | 40S ribosomal protein S27. (102 aa) | ||||
HIPK2 | Homeodomain interacting protein kinase 2. (1205 aa) | ||||
E2F7 | E2F transcription factor 7. (912 aa) | ||||
A0A4W2EYN7 | SEA domain-containing protein. (663 aa) | ||||
GML | UPAR/Ly6 domain-containing protein. (155 aa) | ||||
TFAP4 | Transcription factor AP-4. (335 aa) | ||||
BATF | Basic leucine zipper ATF-like transcription factor. (125 aa) |