50 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLEK	Pleckstrin. (348 aa)
	WDR1	WD repeat domain 1. (606 aa)
	SCIN	Scinderin. (832 aa)
	EPS8	Epidermal growth factor receptor pathway substrate 8. (836 aa)
	TMOD2	Tropomodulin 2. (351 aa)
	LMOD1	Leiomodin 1. (578 aa)
	RDX	Radixin. (624 aa)
	LMOD2	Leiomodin 2. (585 aa)
	CAPZA3	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
	TMOD1	Tropomodulin 1. (359 aa)
	ADD1	Adducin 1. (769 aa)
	TWF2	Twinfilin actin binding protein 2. (349 aa)
	CAPZA1	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	ADD3	Adducin 3. (706 aa)
	PLEKHH2	Pleckstrin homology, MyTH4 and FERM domain containing H2. (1491 aa)
	VIL1	Villin 1. (827 aa)
	TMOD4	Tropomodulin 4. (379 aa)
	MTPN	Myotrophin. (118 aa)
	ADD2	Adducin 2. (724 aa)
	VILL	Villin like. (856 aa)
	SPTBN2	Spectrin beta chain; Belongs to the spectrin family. (2531 aa)
	DEF6	DEF6 guanine nucleotide exchange factor. (701 aa)
	CARMIL1	Capping protein regulator and myosin 1 linker 1. (1426 aa)
	PDXP	Pyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
	CAPG	Capping actin protein, gelsolin like. (412 aa)
	SPTBN4	Spectrin beta, non-erythrocytic 4. (2615 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
	SVIL	Supervillin. (2301 aa)
	SWAP70	Switching B cell complex subunit SWAP70. (585 aa)
	DSTN	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
	SPTAN1	Spectrin alpha, non-erythrocytic 1. (2498 aa)
	TWF1	Twinfilin actin binding protein 1. (368 aa)
	PLEKHH1	Pleckstrin homology, MyTH4 and FERM domain containing H1. (1359 aa)
	DMTN	Dematin actin binding protein. (467 aa)
	SPTB	Spectrin beta chain; Belongs to the spectrin family. (2331 aa)
	KIAA1211	KIAA1211. (1391 aa)
	CAPZB	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (306 aa)
	GSN	Gelsolin. (846 aa)
	LMOD3	Leiomodin 3. (567 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ACTN2	Actinin alpha 2. (894 aa)
	SPTA1	Spectrin alpha, erythrocytic 1. (2419 aa)
	IQANK1	IQ motif and ankyrin repeat containing 1. (591 aa)
	SH3BP1	Uncharacterized protein. (693 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	TMOD3	Tropomodulin 3. (352 aa)
	AVIL	Advillin. (816 aa)
	CAPZA2	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	FLII	FLII actin remodeling protein. (1268 aa)
	LIMA1	LIM domain and actin binding 1. (761 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	CAPZB	A0A4W2DUH9	A0A4W2DGI5	Actinin alpha 2.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.524
ACTN2	TMOD2	A0A4W2DUH9	A0A4W2G2L0	Actinin alpha 2.	Tropomodulin 2.	0.473
ACTN2	TMOD3	A0A4W2DUH9	A0A4W2EB54	Actinin alpha 2.	Tropomodulin 3.	0.473
ACTN2	TMOD4	A0A4W2DUH9	A0A4W2IFP1	Actinin alpha 2.	Tropomodulin 4.	0.493
ADD1	ADD2	A0A4W2HFD7	A0A4W2E7U5	Adducin 1.	Adducin 2.	0.980
ADD1	ADD3	A0A4W2HFD7	A0A4W2HWH8	Adducin 1.	Adducin 3.	0.961
ADD1	CAPZA2	A0A4W2HFD7	A0A4W2EDI5	Adducin 1.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.426
ADD1	CAPZB	A0A4W2HFD7	A0A4W2DGI5	Adducin 1.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.629
ADD1	CFL2	A0A4W2HFD7	A0A4W2E9U1	Adducin 1.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.422
ADD1	DMTN	A0A4W2HFD7	A0A4W2D8V8	Adducin 1.	Dematin actin binding protein.	0.709
ADD1	IQANK1	A0A4W2HFD7	A0A4W2E1X1	Adducin 1.	IQ motif and ankyrin repeat containing 1.	0.442
ADD1	MTPN	A0A4W2HFD7	A0A4W2IIF0	Adducin 1.	Myotrophin.	0.423
ADD1	TMOD1	A0A4W2HFD7	A0A4W2HBG6	Adducin 1.	Tropomodulin 1.	0.778
ADD1	TMOD2	A0A4W2HFD7	A0A4W2G2L0	Adducin 1.	Tropomodulin 2.	0.520
ADD1	TMOD3	A0A4W2HFD7	A0A4W2EB54	Adducin 1.	Tropomodulin 3.	0.573
ADD1	TMOD4	A0A4W2HFD7	A0A4W2IFP1	Adducin 1.	Tropomodulin 4.	0.699
ADD2	ADD1	A0A4W2E7U5	A0A4W2HFD7	Adducin 2.	Adducin 1.	0.980
ADD2	CAPZB	A0A4W2E7U5	A0A4W2DGI5	Adducin 2.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.602
ADD2	DMTN	A0A4W2E7U5	A0A4W2D8V8	Adducin 2.	Dematin actin binding protein.	0.820
ADD2	IQANK1	A0A4W2E7U5	A0A4W2E1X1	Adducin 2.	IQ motif and ankyrin repeat containing 1.	0.414

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